September 2005
Volume 5, Issue 8
Free
Vision Sciences Society Annual Meeting Abstract  |   September 2005
The perceptual effects of retinal electrical stimulation
Author Affiliations
  • Ione Fine
    Department of Ophthalmology and Zilkha Neurogenetic Institute, Keck School of Medicine, USC, 1501 San Pablo Street, Rm 441, Los Angeles, CA 90033
  • Ricardo Freda
    Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, USA
  • Scott H. Greenwald
    Second Sight, Medical Products, Inc., Sylmar, CA
  • Alan Horsager
    Department of Ophthalmology and Zilkha Neurogenetic Institute, Keck School of Medicine, USC, 1501 San Pablo Street, Rm 441, Los Angeles, CA 90033
  • Maksy Pishoy
    Second Sight, Medical Products, Inc., Sylmar, CA
  • Williamson Richard
    Second Sight, Medical Products, Inc., Sylmar, CA
  • Cimmarusti D. Valerie
    Second Sight, Medical Products, Inc., Sylmar, CA
  • Weiland J. James
    Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, USA
  • Greenberg S. Robert
    Second Sight, Medical Products, Inc., Sylmar, CA
  • Humayun Mark
    Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, USA
Journal of Vision September 2005, Vol.5, 366. doi:10.1167/5.8.366
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      Ione Fine, Ricardo Freda, Scott H. Greenwald, Alan Horsager, Maksy Pishoy, Williamson Richard, Cimmarusti D. Valerie, Weiland J. James, Greenberg S. Robert, Humayun Mark; The perceptual effects of retinal electrical stimulation. Journal of Vision 2005;5(8):366. doi: 10.1167/5.8.366.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Photoreceptor loss due to severe retinitis pigmentosa or macular degeneration is one of the major causes of blindness in the Western world,and the prevalence of these diseases is likely to increase dramatically as the population ages. Currently there are several groups trying to develop retinal prostheses, analogous to cochlear implants, in which photoreceptor input is replaced by direct electrical stimulation. Recently six patients have been implanted chronically with simple 4x4 retinal prostheses lying over the inner retinal layer. We report here psychophysical data examining the perceptual consequences of electrical stimulation on a single electrode. These data include (1) how thresholds decrease with pulse duration and decrease as a function of electrode height above the retinal surface, (2) how brightness increases as a function of stimulation intensity, and (3) how pulses interact over time.

Fine, I. Freda, R. Greenwald, S. H. Horsager, A. Pishoy, M. Richard, W. Valerie, C. D. James, W. J. Robert, G. S. Mark, H. (2005). The perceptual effects of retinal electrical stimulation [Abstract]. Journal of Vision, 5(8):366, 366a, http://journalofvision.org/5/8/366/, doi:10.1167/5.8.366. [CrossRef]
Footnotes
 Thanks to Matt McMahon and Kelly McClure
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