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Joana Büchler Costa; Multi-conjugated adaptive optics for wide-field aberration measurement in the human eye. Journal of Vision 2005;5(12):50. doi: 10.1167/5.12.50.
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Recent improvements in retinal imaging have shown that adaptive optics is a very useful technique for gaining resolution in imaging and in stimulating the human retina in-vivo. Till now the adaptive optical correction has been restricted to a small field of view, since the optical aberrations of the eye are only accessible in the direction of the measuring beam. Therefore the correction is limited by the isoplanatic angle which depends on the optical quality of the complete eye. We study the possibility of enlarging the corrected field of view using multi-conjugated adaptive optics techniques, which allow for a 3-dimensional tomographical reconstruction of the aberration volume. There can be considered more than one distinct refractive surfaces in the eye, like the corneal and lens surfaces. In this way the origin and dynamics of the aberrations can be separately analyzed, using three or more measuring beams and at least two wavefront correctors to achieve a wide-field correction. The standard technique, using one measuring beam and one wavefront corrector, is compared to this new approach in terms of imaging quality. The analysis is done through numerical simulations using data from wide-field eye models and published wavefront aberration measurements across the visual field.
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