December 2006
Volume 6, Issue 13
Free
OSA Fall Vision Meeting Abstract  |   December 2006
High-resolution imaging of retinal disease and their retinal function
Author Affiliations
  • Stacey S. Choi
    Department of Ophthalmology & Vision Science, University of California Davis, Sacramento, CA 95817
  • Robert J. Zawadzki
    Ophthalmology and Vision Science, University of California Davis
  • John S. Werner
    Ophthalmology and Vision Science, University of California Davis
Journal of Vision December 2006, Vol.6, 37. doi:10.1167/6.13.37
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Stacey S. Choi, Robert J. Zawadzki, John S. Werner; High-resolution imaging of retinal disease and their retinal function. Journal of Vision 2006;6(13):37. doi: 10.1167/6.13.37.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Patients with variety of retinal diseases were evaluated with high-resolution imaging instruments constructed at UC Davis and by testing retinal functions. Functional tests included multifocal electroretinogram (mfERG), color vision, visual fields and contrast sensitivity using stimuli presented at the locations corresponding to retinal imaging. The imaging instruments included: (1) adaptive optics (AO) flood-illumination which results in approximately 2 µm lateral resolution, (2) Fourier-domain optical coherence tomography (Fd-OCT) providing high speed (9–36 frames/sec) B-scans with either ∼3, 4.5 or 6 µm axial resolution and 15 µm lateral resolution and (3) AO - Fd-OCT which has both high-lateral (3.5 µm) and high-axial (6 µm) resolution. Both AO instruments revealed changes in the cone photoreceptors, which correlated with localized functional changes. Due to the high speed of Fd-OCT, it is possible to acquire volumetric data of retinal structures. The 3D reconstruction of retina revealed structures that have not been visualized with commercial instruments.

Choi, S. S. Zawadzki, R. J. Werner, J. S. (2006). High-resolution imaging of retinal disease and their retinal function [Abstract]. Journal of Vision, 6(13):37, 37a, http://journalofvision.org/6/13/37/, doi:10.1167/6.13.37. [CrossRef] [PubMed]
Footnotes
 Supported by NEI 014743, RPB
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×