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Jianliang Tong, Bin Zhang, Jianghe Zheng, Earl L. Smith, III, Yuzo M. Chino; TimeCourse of surround suppression in V2 neurons of Macaque monkeys. Journal of Vision 2007;7(9):76. doi: 10.1167/7.9.76.
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© ARVO (1962-2015); The Authors (2016-present)
In macaque V1, stimulation of the receptive field (RF) surround of a neuron strongly suppresses the responses initiated by stimulation of its classical RF (CRF). Although the exact nature of circuits responsible for surround suppression is still a matter of considerable debate, investigating the time course of surround suppression is a useful means to reveal underlying cortical circuits for suppression (Bair et al, 2003). The previous investigators found that latency of suppression depends on its strength. We previously reported that V2 neurons have similar center/surround organization but exhibit stronger surround suppression than V1 neurons (Zhang et al, 2005). In this study using dynamic center-surround stimuli similar to those developed by Bair et al (2003), we examined the time course of surround suppression in 180 V2 neurons and compared to that in 125 V1 neurons in order to determine whether latency of surround suppression is shorter in V2 than in V1 and also how the timing of center/surround responses are different between V1 and V2. We found that the relative latencies of surround suppression and release in V2 were not significantly different from those in V1, and that suppression latency in V2 was generally longer for those units with weaker surround suppression with some notable exceptions. This relationship between suppression latency and the strength of suppression was stronger in V2 than in V1. Other aspects of the timing of center/surround responses were remarkably similar between V1 and V2. These results suggest that circuits in V2 for surround suppression are likely to be similar to those in V1 except that the functional connections supporting surround suppression in V2 are functionally more robust than those in V1.
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