December 2005
Volume 5, Issue 12
Free
OSA Fall Vision Meeting Abstract  |   December 2005
S-cone signals in human postreceptoral pathways
Author Affiliations
  • Andrew Stockman
    Institute of Ophthalmology, University College London
Journal of Vision December 2005, Vol.5, 19. doi:https://doi.org/10.1167/5.12.19
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      Andrew Stockman; S-cone signals in human postreceptoral pathways. Journal of Vision 2005;5(12):19. https://doi.org/10.1167/5.12.19.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

In addition to their expected chromatic contribution, the S-cones make a small contribution to luminance, revealed when the S-cone response is relatively enhanced by intense long-wavelength adaptation. Under such conditions, the S-cone contribution is negative (−S) and also substantially delayed. This slow input is not unique to the S-cones: we and others have identified M- and L-cone inputs with comparable temporal properties. These inputs appear as spectrally-opponent pairs, which can be either +L−M or +M−L, depending on the adaptation conditions. This raises the interesting possibility that the −S input found under long-wavelength adaptation might be complemented by a +S input under other conditions, a speculation reinforced by recent physiological evidence for a +S (or S-ON) input to magnocellular cells. To date, however, we have been unable to find any psychophysical evidence for a positive S-cone contribution to luminance.

One concern is that the negative S-cone input to luminance can be misidentified as +S due to its substantial delay. Such a mistake is easy to make: depending on the adaptation conditions, the phase delay of the −S input can cause it to add to luminance at frequencies as low as 5 Hz and as high as 25 Hz despite its negative sign. To be certain of the sign of the S-cone input, measurements must be extended to temporal frequencies that are low enough for the phase delay of the S-cone signal to be extrapolated to 0 Hz, where its sign is unambiguously revealed.

Stockman, A. (2005). S-cone signals in human postreceptoral pathways [Abstract]. Journal of Vision, 5(12):19, 19a, http://journalofvision.org/5/12/19/, doi:10.1167/5.12.19. [CrossRef]
Footnotes
 Supported by the Wellcome Trust
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