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Leslie Ungerleider; Perceptual decision-making in the human brain. Journal of Vision 2005;5(12):44. doi: https://doi.org/10.1167/5.12.44.
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Findings from single-cell recording studies suggest that a comparison of the outputs of different pools of selectively tuned lower-level sensory neurons may be a general mechanism by which higher-level cortical regions compute perceptual decisions. For example, when monkeys must decide whether a noisy field of dots is moving upward or downward, a decision can be formed by computing the difference in responses between lower-level neurons sensitive to upward motion and those sensitive to downward motion. I will present fMRI evidence that even for high-level object categories, the comparison of the outputs of different pools of selectively tuned neurons could be a general mechanism by which the human brain computes perceptual decisions. Furthermore, I will argue that the posterior dorsolateral prefrontal cortex in humans has general decision-making functions, independent of stimulus and response modalities.
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