Abstract
Time series of the first to fourth order of Zernike modes of wave aberrations for both eyes were investigated with an open-view binocular Shack Hartmann wavefront sensor. The sampling rate was 24 times a second and the duration of the measurement was 12 seconds. A landscape picture was presented at the far point of each subject during measurement. Two normal subjects in their thirties were measured. For each subject, time series of wavefront aberrations were measured in a normal condition. After one drop of Mydrin-P (containing 0.5% tropicamide and 0.5% phenylephrine) was applied, time series of wavefront aberrations were measured again. After the time series of each mode were differenced to achieve a statistically stationary condition, standard deviations and power spectra were calculated. The standard deviation of the defocus term with cycloplegia was largest. A correlation between left eye and right eye in low frequency ([[lt]] 3 Hz) was found only in defocus mode without cycloplegia. With cycloplegia, the correlation was lost and the cross spectrum of the defocus mode was similar to those of the other modes. We speculate that the slow change in time series of defocus was from activity of the autonomic nervous system.