December 2013
Volume 13, Issue 15
Free
OSA Fall Vision Meeting Abstract  |   October 2013
Crystalline lens may be distorted when the unilateral ciliary nerves are stimulated
Author Affiliations
  • Toshifumi Mihashi
    Innovative Research Initiatives, Tokyo Institute of Technology
  • Suguru Miyagawa
    Optical Engineering Laboratory, Topcon Corporation
  • Yoko Hirohara
    Optical Engineering Laboratory, Topcon Corporation
  • Takao Endo
    Applied Visual Science, Osaka University Graduate School of Medicine
  • Hiroyuki Kanda
    Applied Visual Science, Osaka University Graduate School of Medicine
  • Tomomitsu Miyoshi
    Integrative Physiology, Osaka University Graduate School of Medicine
  • Takashi Fujikado
    Applied Visual Science, Osaka University Graduate School of Medicine
Journal of Vision October 2013, Vol.13, P23. doi:https://doi.org/10.1167/13.15.58
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    • Get Citation

      Toshifumi Mihashi, Suguru Miyagawa, Yoko Hirohara, Takao Endo, Hiroyuki Kanda, Tomomitsu Miyoshi, Takashi Fujikado; Crystalline lens may be distorted when the unilateral ciliary nerves are stimulated. Journal of Vision 2013;13(15):P23. https://doi.org/10.1167/13.15.58.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The pupil dilated asymmetrically when one side of the ciliary nerve was stimulated in cats (Miyagawa, 2013, ARVO). To investigate the changes of higher order aberration elicited by electrical stimulation of the ciliary nerve, we analyzed the wavefront aberrations with a compact Shack-Hartmann wavefrontaberrometer (Aston University and Topcon Corp.) before, during, and after the stimulation. Six eyes of six cats were studied under general anesthesia. Trains of monophasic pulse were applied to either the lateral branch (LB) or medial branch (MB) of the short ciliary nerve with hook-shaped bipolar stimulating electrodes. We measured the wavefront aberration for 2 seconds before, 8 seconds during, and for 20 seconds after the electrical stimulation. We performed the wavefront sensing over 6-mm pupil area when one side of the ciliary nerve was stimulated. Among four of astigmatism and coma terms in Zernike modes, only oblique astigmatism (OA) but not coma was statistically significantly different between the LB stimulation and the MB stimulation. The OA induced by the LB was −0.098 ± 0.086 (average ± SD) μm and OA induced by the MD was 0.086 ± 0.038 μm. This results suggested that the unilateral ciliary nerve stimulation induced asymmetrical contraction of the ciliary body and this caused distortion of the crystalline lens shape rather than shift of the lens.

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