October 2020
Volume 20, Issue 11
Open Access
Vision Sciences Society Annual Meeting Abstract  |   October 2020
Dissociated face- and word-selective intracerebral responses in the human ventral occipito-temporal cortex
Author Affiliations
  • Simen Hagen
    Universite de Lorraine, CNRS, CRAN, F-54000 Nancy, France
  • Aliette Lochy
    Cognitive Science and Assessment Institute, University of Luxembourg
  • Corentin Jacques
    Psychological Sciences Research Institute and Institute of Neuroscience, University of Louvain, B-1348 Louvain-La-Neuve, Belgium
  • Louis Maillard
    Universite de Lorraine, CNRS, CRAN, F-54000 Nancy, France
    Universite de Lorraine, CHRU-Nancy, Service de Neurologie, F-54000 Nancy, France
  • Sophie Colnat-Coulbois
    Universite de Lorraine, CNRS, CRAN, F-54000 Nancy, France
    Universite de Lorraine, CHRU-Nancy, Service de Neurochirurgie, F-54000 Nancy, France
  • Jacques Jonas
    Universite de Lorraine, CNRS, CRAN, F-54000 Nancy, France
    Universite de Lorraine, CHRU-Nancy, Service de Neurologie, F-54000 Nancy, France
  • Bruno Rossion
    Universite de Lorraine, CNRS, CRAN, F-54000 Nancy, France
    Psychological Sciences Research Institute and Institute of Neuroscience, University of Louvain, B-1348 Louvain-La-Neuve, Belgium
    Universite de Lorraine, CHRU-Nancy, Service de Neurologie, F-54000 Nancy, France
Journal of Vision October 2020, Vol.20, 713. doi:https://doi.org/10.1167/jov.20.11.713
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Simen Hagen, Aliette Lochy, Corentin Jacques, Louis Maillard, Sophie Colnat-Coulbois, Jacques Jonas, Bruno Rossion; Dissociated face- and word-selective intracerebral responses in the human ventral occipito-temporal cortex. Journal of Vision 2020;20(11):713. doi: https://doi.org/10.1167/jov.20.11.713.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

The extent to which faces and written words share neural circuitry in the human brain is actively debated. We provide an original contribution to this debate by comparing face-selective and word-selective responses in a large group of patients (N=37) implanted with intracerebral electrodes in the ventral occipito-temporal cortex (VOTC). Both face-selective (i.e., significantly different responses to faces vs. nonface objects) and word-selective (i.e., significantly different responses to words vs. pseudofonts) neural activity is isolated through frequency-tagging (Jonas et al., 2016; Lochy et al., 2018, respectively). Critically, this approach allows disentangling category-selective neural responses from general visual responses. Overall, we find that 69.26% of significant contacts show either face- or word-selectivity, with the expected right and left hemispheric dominance, respectively (Fig.1A,B). Moreover, the center of mass for word-contacts is more lateral than for face-contacts, with no differences in postero-anterior axis (Fig.2A). Spatial dissociations are also found within core regions of face and word processing, with a medio-lateral dissociation in the fusiform gyrus (FG) and surrounding sulci (FG+sulci;Fig.2B), while a postero-anterior dissociation is found in the inferior occipital gyrus (IOG;Fig.2C). Despite their spatial dissociations in the FG+sulci and IOG, most overlap in category-selective responses is found in these regions (Fig.1C). Critically, in the overlap-contacts, across the whole brain or specifically in the FG+sulci, between-category (word-face) selective-amplitudes showed no-to-weak correlations, despite strong correlations for within-category (face-face, word-word) selective-amplitudes (Fig.3A), and a strong correlation in non-selective general-amplitudes to words-faces. Moreover, substantial overlap and no-to-weak correlations were observed between faces and a control category (houses) known to be functionally dissociated from faces. Overall, we conclude that category-selectivity for faces and words is largely dissociated in the human VOTC, with a limited spatial overlap likely due to the distant recording of dissociated populations of neurons rather than to shared category-selective representations.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×