September 2021
Volume 21, Issue 9
Open Access
Vision Sciences Society Annual Meeting Abstract  |   September 2021
What do distinct parietal neural responses for face and motion discrimination tasks reveal about the mechanisms of the decision-making process?
Author Affiliations & Notes
  • Gouki Okazawa
    New York University
  • Christina Hatch
    New York University
  • Allan Mancoo
    Champalimaud Centre for the Unknown
  • Christian Machens
    Champalimaud Centre for the Unknown
  • Roozbeh Kiani
    New York University
  • Footnotes
    Acknowledgements  We thank the following grant supports: NIH Grant R01MH109180; Sloan Fellowship; McKnight Scholar Award; Charles H. Revson Foundation; Japan Society for the Promotion of Science
Journal of Vision September 2021, Vol.21, 2186. doi:https://doi.org/10.1167/jov.21.9.2186
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      Gouki Okazawa, Christina Hatch, Allan Mancoo, Christian Machens, Roozbeh Kiani; What do distinct parietal neural responses for face and motion discrimination tasks reveal about the mechanisms of the decision-making process?. Journal of Vision 2021;21(9):2186. https://doi.org/10.1167/jov.21.9.2186.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The firing rate of macaque lateral intraparietal (LIP) neurons encodes the decision variable (DV) for perceptual decisions reported through saccadic eye movements in a random dot direction discrimination task (Shadlen & Newsome, 2001). In circuit models for these decisions, neural ensembles that encode actions compete to form decisions. Consequently, DVs are represented as partially enabled action plans, where ensembles increase their average responses for stronger evidence supporting their preferred actions. As another consequence, DV representation and readout are implemented similarly for different inputs and task contexts when decisions are communicated through the same actions. Here, we examined these assumptions by comparing LIP responses between the motion discrimination task and a novel face discrimination task. Unlike in the motion task, average LIP firing rates during face discrimination were lower for stronger stimuli supporting the preferred saccade target of the recorded neurons, contradicting existing theories. This marked difference in average responses, however, did not indicate different underlying computations between the tasks; population response patterns in both tasks monotonically encoded the DV on a curved manifold in the state space, representing the integration of sensory evidence. This curved manifold rotated and shifted in a task-dependent manner, leading to the opposing trends of average firing rates in the two tasks. These newly discovered properties of LIP activity are not explained by existing circuit models, necessitating development of new models that incorporate task-dependent computations. Furthermore, the curvature of manifold encoding the DV was not limited to LIP; similar curved manifolds were discovered in the lateral and medial frontal cortical regions. This indicates a ubiquitous computational mechanism across the frontoparietal regions that underlies the observed geometry of the DV encoding.

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