December 2022
Volume 22, Issue 14
Open Access
Vision Sciences Society Annual Meeting Abstract  |   December 2022
Can face recollection be improved in developmental prosopagnosia? Evidence from a novel repetition-lag training program
Author Affiliations
  • Regan Fry
    Department of Psychiatry, Harvard Medical School, Boston MA
    Boston Attention and Learning Lab, Boston VA Healthcare System, Boston MA
  • Mieke Verfaellie
    Memory Disorders Research Center, Boston VA Healthcare System, Boston MA
    Department of Psychiatry, Boston University School of Medicine, Boston MA
  • Nicole Anderson
    Rotman Research Institute, Baycrest, Toronto, Ontario, Canada
    Departments of Psychology and Psychiatry, University of Toronto, Ontario, Canada
  • Joseph DeGutis
    Department of Psychiatry, Harvard Medical School, Boston MA
    Boston Attention and Learning Lab, Boston VA Healthcare System, Boston MA
Journal of Vision December 2022, Vol.22, 3361. doi:https://doi.org/10.1167/jov.22.14.3361
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      Regan Fry, Mieke Verfaellie, Nicole Anderson, Joseph DeGutis; Can face recollection be improved in developmental prosopagnosia? Evidence from a novel repetition-lag training program. Journal of Vision 2022;22(14):3361. https://doi.org/10.1167/jov.22.14.3361.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Previous studies have demonstrated that perceptual training can improve face processing in individuals with developmental prosopagnosia (DP). However, training face memory has only been attempted in a few prosopagnosia cases, with mixed success. We recently showed that face recollection, the all-or-none recognition with associated contextual information, is deficient in DPs. Further, we have found evidence for the existence of two subgroups of DP: perceptually impaired (PI-DP) and perceptually unimpaired (PU-DP), suggesting that memory impairments may underlie impairment in the latter group. To investigate whether training could improve face recollection and whether this differed between DP subgroups, in the current study we used a novel four-week-long repetition-lag training program targeting face recollection following four weeks of perceptual training in 14 individuals with DP (Age: M=42.8, SD=12.9). Participants completed an extensive battery of tests assessing face perception and memory prior to the eight weeks of training and assessment immediately after as well as six weeks post-training. Immediately following training, we observed significant group-level improvements in the Cambridge Face Memory Test (Pre: M=.54, SD=.09, Post: M=.61, SD=.13; p=.002). Face recollection in a remember/know task improved numerically but not significantly (Pre: M=.51, SD=.38, Post: M=.75, SD=.25; p=.088). Notably, PU-DPs showed a numerical improvement in face recollection (Pre: M=.59, SD=.43, Post: M=.88, SD=.23) that reached levels comparable to the recollection mean of typically developing controls (TD: M=.88, SD=.12). PU-DPs also showed significantly improved source recall on the trials where they correctly remembered a face (Pre: M=.63, SD=.34, Post: M=.95, SD=.09; p=.049). Face recollection improvements persisted in the entire sample at the 6-week post-training follow-up (M=.80, SD=.33). Together, these findings provide important 'proof of concept' that repetition-lag training can improve face recollection, a critical memory deficit in DPs. The effects were particularly apparent in PU-DPs and suggest applying different treatment approaches to PI-DPs vs. PU-DPs.

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