December 2023
Volume 23, Issue 15
Open Access
Optica Fall Vision Meeting Abstract  |   December 2023
Boynton Lecture: Wiring specificity and plasticity of the vertebrate retina
Author Affiliations
  • Rachel Wong
    Department of Biological Structure, University of Washington
Journal of Vision December 2023, Vol.23, 2. doi:
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      Rachel Wong; Boynton Lecture: Wiring specificity and plasticity of the vertebrate retina. Journal of Vision 2023;23(15):2.

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      © ARVO (1962-2015); The Authors (2016-present)

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Vision relies on the output of the many functionally distinct and precisely wired circuits of the retina. Using transgenic techniques, imaging methods and electrophysiology, we seek to uncover the developmental mechanisms that help establish the wiring specificity of retinal circuits in vertebrates. Moreover, because injury or disease can cause rewiring after maturation, we are also reconstructing primate retinal circuits impacted by the loss of input, in order to identify the challenges to circuit repair.

 Funding: Funding: Supported by NIH EY10699, EY033447 and EY01730

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