September 2024
Volume 24, Issue 10
Open Access
Vision Sciences Society Annual Meeting Abstract  |   September 2024
Interaction Between the Prefrontal and Visual Cortices Supports Subjective Fear
Author Affiliations
  • Vincent Taschereau-Dumouchel
    Department of Psychiatry and Addictology, Université de Montréal
    Centre de Recherche de l’Institut Universitaire en Santé Mentale de Montréal
  • Marjorie Côté
    Department of Psychiatry and Addictology, Université de Montréal
    Centre de Recherche de l’Institut Universitaire en Santé Mentale de Montréal
  • Shawn Manuel
    Department of Psychiatry and Addictology, Université de Montréal
    Centre de Recherche de l’Institut Universitaire en Santé Mentale de Montréal
  • Valevicius Darius
    Department of Psychiatry and Addictology, Université de Montréal
    Centre de Recherche de l’Institut Universitaire en Santé Mentale de Montréal
  • Hakwan Lau
    RIKEN Center for Brain Science
Journal of Vision September 2024, Vol.24, 892. doi:https://doi.org/10.1167/jov.24.10.892
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      Vincent Taschereau-Dumouchel, Marjorie Côté, Shawn Manuel, Valevicius Darius, Hakwan Lau; Interaction Between the Prefrontal and Visual Cortices Supports Subjective Fear. Journal of Vision 2024;24(10):892. https://doi.org/10.1167/jov.24.10.892.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

It has been reported that threatening and non-threatening visual stimuli can be distinguished based on multi-voxel patterns of hemodynamic activity in the human ventral visual stream. Do these findings mean that there may be evolutionarily hardwired mechanisms within early perception, for the fast and automatic detection of threat, and maybe even for the generation of the subjective experience of fear? In this study, we provide evidence using human neuroimaging that the ventral visual stream may represent affectively neutral visual features that are statistically associated with fear ratings of participants, without representing the subjective experience of fear itself. More specifically, we show that patterns of hemodynamic activity predictive of a specific “fear profile” (i.e., fear ratings reported by a given participant) can be observed in the ventral visual stream whether a participant reports being afraid of the stimuli or not. Further, we found that the multivariate information transmission between ventral visual areas and prefrontal regions distinguished participants who reported being subjectively afraid of the stimuli from those who did not. Together, these findings support the view that the subjective experience of fear may depend on the relevant visual information triggering implicit metacognitive mechanisms in the prefrontal cortex.

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