September 2024
Volume 24, Issue 10
Open Access
Vision Sciences Society Annual Meeting Abstract  |   September 2024
Differential saccade related modulations in marmoset V1 across cell layers and types
Author Affiliations & Notes
  • Neya More
  • Yonatan Abrham
  • Amy Bucklaew
    Brain and Cognitive Sciences, University of Rochester
    Neuroscience Graduate Program, University of Rochester
  • Jude Mitchell
    Brain and Cognitive Sciences, University of Rochester
    Neuroscience Graduate Program, University of Rochester
  • Footnotes
    Acknowledgements  Funding: NIH EY030998, AB from NIH T32EY007125
Journal of Vision September 2024, Vol.24, 1152. doi:https://doi.org/10.1167/jov.24.10.1152
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      Neya More, Yonatan Abrham, Amy Bucklaew, Jude Mitchell; Differential saccade related modulations in marmoset V1 across cell layers and types. Journal of Vision 2024;24(10):1152. https://doi.org/10.1167/jov.24.10.1152.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Marmoset monkeys have high acuity foveal vision and use saccadic eye movements to rapidly sample across visual locations. Each eye movement produces a wave of neural activity in primary visual cortex that includes saccadic suppression starting from the saccade onset followed by a positive post-saccadic rebound. Across the population the amplitude of suppression and rebound varied considerably, as well as latency of these components (Parker et al., 2023). Here, we investigated how saccadic-related neural responses were related to different cell types in V1 focusing on distinctions by cortical layer (superficial, input, and deep) and by spike waveform shape (narrow and broad). We used linear silicon arrays to record well isolated single units across laminar depths in one monkey that freely viewed either natural images or a blank screen. We found that narrow and broad spiking waveforms were distributed bi-modally as found in previous studies, but this was only the case in superficial and deep layers. By contrast, the input layer showed a unimodal distribution of durations which could reflect underlying differences in its anatomy as the V1 input layer is distinguished by stellate neurons and calbindin expressing inhibitory neurons (Bourne et al, 2007). We found the saccade modulation among narrow spiking neurons in all layers showed little suppression and had earlier latency positive responses. The differences between narrow and broad spiking responses were weaker but significant in the input layer, and grew the strongest in deeper layers, where narrow spiking cells showed the earliest positive responses. These early positive responses among narrow spiking cells could play a role in mediating suppression to the other cell classes.

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