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Retina December 2022

Fluorescence Lifetime and Spectral Characteristics of Subretinal Drusenoid Deposits and Their Predictive Value for Progression of Age-Related Macular Degeneration

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Sebastian Weber; Rowena Simon; Linda-Sophia Schwanengel; Christine A. Curcio; Regine Augsten; Daniel Meller; Martin Hammer
TAGS: age-related macular degeneration, digestive tract decontamination, fluorescence, predictive value
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):23. doi: https://doi.org/10.1167/iovs.63.13.23

Includes: Supplemental Content

Retinal Cell Biology December 2022

Prolonged Lifetimes of Histologic Autofluorescence in Ectopic Retinal Pigment Epithelium in Age-Related Macular Degeneration

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Rowena Simon; Marius Jentsch; Parva Karimimousivandi; Dongfeng Cao; Jeffrey D. Messinger; Daniel Meller; Christine A. Curcio; Martin Hammer
TAGS: age-related macular degeneration, autofluorescence, retinal pigment epithelium, fluorescence, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):5. doi: https://doi.org/10.1167/iovs.63.13.5

Includes: Supplemental Content

Retina October 2022

Impact of the Aging Lens and Posterior Capsular Opacification on Quantitative Autofluorescence Imaging in Age-Related Macular Degeneration

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Andreas Berlin; Mark E. Clark; Thomas A. Swain; Nathan A. Fischer; Gerald McGwin, Jr; Kenneth R. Sloan; Cynthia Owsley; Christine A. Curcio
TAGS: age-related macular degeneration, aging, autofluorescence, diagnostic imaging, eye, lens (device), lens, crystalline, opacification, pseudophakia
Trans. Vis. Sci. Tech.. 2022; 11(10):23. doi: https://doi.org/10.1167/tvst.11.10.23

Includes: Supplemental Content

Retina August 2022

Histologic Cell Shape Descriptors for the Retinal Pigment Epithelium in Age-Related Macular Degeneration: A Comparison to Unaffected Eyes

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Leon von der Emde; Marc Vaisband; Jan Hasenauer; Leonie Bourauel; Katharina Bermond; Marlene Saßmannshausen; Rainer Heintzmann; Frank G. Holz; Christine A. Curcio; Kenneth R. Sloan; Thomas Ach
TAGS: age-related macular degeneration, aging, eye, language morphology, morphology, retinal pigment cell, retinal pigment epithelium, shape, donors
Trans. Vis. Sci. Tech.. 2022; 11(8):19. doi: https://doi.org/10.1167/tvst.11.8.19

Retina July 2022

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

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Cynthia Owsley; Thomas A. Swain; Gerald McGwin, Jr.; Mark E. Clark; Deepayan Kar; Jason N. Crosson; Christine A. Curcio
TAGS: age-related macular degeneration, aging, eye, vision, digestive tract decontamination
Trans. Vis. Sci. Tech.. 2022; 11(7):17. doi: https://doi.org/10.1167/tvst.11.7.17

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2022

Retinal Pigment Epithelium in Human Donor Eyes Contains Higher Levels of Bisretinoids Including A2E in Periphery than Macula

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Ankita Kotnala; Srinivasan Senthilkumari; Gong Wu; Thomas G. Stewart; Christine A. Curcio; Nabanita Halder; Sundararajan Baskar Singh; Atul Kumar; Thirumurthy Velpandian
TAGS: donors, eye, macula lutea, retina, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):6. doi: https://doi.org/10.1167/iovs.63.6.6

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Three-dimensional reconstruction of human retinal pigment epithelium (RPE) permits a novel view of the RPE – photoreceptor outer segment (OS) interface

Andreas Pollreisz; Aleksandra Sedova; Maximilian Lindell; Zachary Arsenault; Orin Packer; Deepayan Kar; Yeon Jin Kim; Kenneth R Sloan; Ursula Schmidt-Erfurth; Mike Marsh; Christine A Curcio; Dennis M Dacey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):871. doi:

ARVO Annual Meeting Abstract June 2022

Associations of rod-mediated dark adaptation measures in older adults without AMD or with early or intermediate AMD, baseline results from the ALSTAR2 study

Thomas A. Swain; Gerald McGwin; Mark Clark; Christine A Curcio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):351 – F0182. doi:

ARVO Annual Meeting Abstract June 2022

Accuracy of Deep-Learning-Derived OCT Retinal Layer Segmentation in the Alabama Study on Early Age-Related Macular Degeneration 2 (ALSTAR2)

Sohaib Fasih-Ahmad; Ziyuan Wang; Zubin Mishra; Charles Vatanatham; Anjal M Jain; Anushika Ganegoda; Zhihong Jewel Hu; Mark Clark; Cynthia Owsley; Christine A Curcio; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2075 – F0064. doi:

ARVO Annual Meeting Abstract June 2022

Comparison of OCT retinal layer properties in normal and early AMD in the Alabama study on early age-related macular degeneration 2 (ALSTAR2)

Chaiyaporn C Vatanatham; Ziyuan Wang; Zubin Mishra; Sohaib Fasih-Ahmad; Anjal Jain; Anushika Ganegoda; Zhihong Hu; Mark Clark; Cynthia Owsley; Christine A Curcio; Srinivas R Sadda

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1042 – F0289. doi:

ARVO Annual Meeting Abstract June 2022

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Charles Dwight Evers III; Ling Chen; Jeffrey D Messinger; Diogo Cabral; Rosa Dolz-Marco; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1021 – F0268. doi:

ARVO Annual Meeting Abstract June 2022

Impact of Cataract Surgery on Rod-Mediated Dark Adaptation in Older Adults

Tarushi Tanaya; Andreas Berlin; Thomas A. Swain; Gerald McGwin; Mark Clark; Michael A Callahan; Virginia Lolley; Jason Swanner; Christine A Curcio; Cynthia Owsley

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):329 – F0160. doi:

ARVO Annual Meeting Abstract June 2022

Intact transthyretin proteoforms of intraocular origin in human subretinal fluid from rhegmatogenous retinal detachment

Jianzhong Chen; Dongfeng Cao; Seth Fortmann; Christine A Curcio; Richard Feist; Jason Crosson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1183 – A0037. doi:

ARVO Annual Meeting Abstract June 2022

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Andreas Berlin; Diogo Cabral; Ling Chen; Jeffrey D Messinger; Chandrakumar Balaratnasingam; Randev Mendis; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1018 – F0265. doi:

ARVO Annual Meeting Abstract June 2022

Quantitative autofluorescence (qAF) is not associated with early and intermediate age-related macular degeneration (AMD) in pseudophakic eyes of the ALSTAR2 baseline cohort

Nathan Fischer; Andreas Berlin; Mark Clark; Thomas A. Swain; Gerald McGwin; Kenneth R Sloan; Jason Crosson; Cynthia Owsley; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1017 – F0264. doi:

ARVO Annual Meeting Abstract June 2022

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Dongfeng Cao; Jeffrey D Messinger; Deepayan Kar; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2584 – F0467. doi:

ARVO Annual Meeting Abstract June 2022

Lipid localization and identification in human retina with subretinal drusenoid deposits (SDD) using LC-MS/MS and MALDI-IMS

Ankita Kotnala; David M.G. Anderson; Sara Tortorella; Jeffrey Messinger; Christine A Curcio; Kevin L Schey

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4622 – F0414. doi:

ARVO Annual Meeting Abstract June 2022

Spectral Analysis of Human Retinal Pigment Epithelium Cells in Healthy and AMD Affected Eyes

Leonie Bourauel; Marc Vaisband; Leon Alexander von der Emde; Katharina Bermond; Ioana Sandra Tarau; Marlene Sassmannshausen; Rainer Heintzmann; Frank G Holz; Christine A Curcio; Jan Hasenauer; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4621 – F0413. doi:

ARVO Annual Meeting Abstract June 2022

Histologic cell shape descriptors for the retinal pigment epithelium in age-related macular degeneration

Leon Alexander von der Emde; Marc Vaisband; Jan Hasenauer; Leonie Bourauel; Marlene Sassmannshausen; Katharina Bermond; Rainer Heintzmann; Frank G Holz; Christine A Curcio; Kenneth R Sloan; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4508 – F0295. doi:

ARVO Annual Meeting Abstract June 2022

A Conceptual Framework for Visual Function Impairment from Normal Aging to Early and Intermediate AMD: ALSTAR2 Cross-sectional Results

Cynthia Owsley; Thomas A. Swain; Gerald McGwin; Mark Clark; Jason Crosson; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):878. doi:

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Fluorescence Lifetime and Spectral Characteristics of Subretinal Drusenoid Deposits and Their Predictive Value for Progression of Age-Related Macular Degeneration

Prolonged Lifetimes of Histologic Autofluorescence in Ectopic Retinal Pigment Epithelium in Age-Related Macular Degeneration

Impact of the Aging Lens and Posterior Capsular Opacification on Quantitative Autofluorescence Imaging in Age-Related Macular Degeneration

Histologic Cell Shape Descriptors for the Retinal Pigment Epithelium in Age-Related Macular Degeneration: A Comparison to Unaffected Eyes

How Vision Is Impaired From Aging to Early and Intermediate Age-Related Macular Degeneration: Insights From ALSTAR2 Baseline

Retinal Pigment Epithelium in Human Donor Eyes Contains Higher Levels of Bisretinoids Including A2E in Periphery than Macula

Three-dimensional reconstruction of human retinal pigment epithelium (RPE) permits a novel view of the RPE – photoreceptor outer segment (OS) interface

Associations of rod-mediated dark adaptation measures in older adults without AMD or with early or intermediate AMD, baseline results from the ALSTAR2 study

Accuracy of Deep-Learning-Derived OCT Retinal Layer Segmentation in the Alabama Study on Early Age-Related Macular Degeneration 2 (ALSTAR2)

Comparison of OCT retinal layer properties in normal and early AMD in the Alabama study on early age-related macular degeneration 2 (ALSTAR2)

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Impact of Cataract Surgery on Rod-Mediated Dark Adaptation in Older Adults

Intact transthyretin proteoforms of intraocular origin in human subretinal fluid from rhegmatogenous retinal detachment

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Quantitative autofluorescence (qAF) is not associated with early and intermediate age-related macular degeneration (AMD) in pseudophakic eyes of the ALSTAR2 baseline cohort

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Lipid localization and identification in human retina with subretinal drusenoid deposits (SDD) using LC-MS/MS and MALDI-IMS

Spectral Analysis of Human Retinal Pigment Epithelium Cells in Healthy and AMD Affected Eyes

Histologic cell shape descriptors for the retinal pigment epithelium in age-related macular degeneration

A Conceptual Framework for Visual Function Impairment from Normal Aging to Early and Intermediate AMD: ALSTAR2 Cross-sectional Results

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