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ARVO Annual Meeting Abstract June 2024

Eye on Genome Editing

Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):7.

ARVO Annual Meeting Abstract June 2024

Knocking down liver transthyretin (TTR) via RNAi leads to decreased A2E in the eyes of Abca4 -/- Rdh8 -/- mice, a model of Stargardt disease

Grazyna Palczewska; Simina Ticau; Elena Castellanos-Rizaldos; David Erbe; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):202.

ARVO Annual Meeting Abstract June 2024

Exploring the role of Adiponectin Receptor 1 in the dynamics of omega-3 fatty acid metabolism

Dominik Lewandowski; Fangyuan Gao; Sanae Imanishi; Aleksander Tworak; Marco Bassetto; Zhiqian Dong; Antonio FM Pinto; Marcin Tabaka; Philip David Kiser; Yoshikazu Imanishi; Dorota Skowronska-Krawczyk; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):185.

ARVO Annual Meeting Abstract June 2024

Role of O -glycosylation at the N-terminus of green and red cone opsins

David Salom; Dominik Lewandowski; Alexander V Kolesnikov; Vladimir Kefalov; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1336.

ARVO Annual Meeting Abstract June 2024

Efficient and therapeutic RPE prime editing via novel engineered virus-like particles

Samuel Wang Du; Meirui An; Aditya Raguram; David Liu; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1028.

ARVO Annual Meeting Abstract June 2024

Modulation of mouse rod function by a llama-derived transducin nanobody

Deepak Poria; Jennings Luu; Aneal Singh; Fangyuan Gao; Krzysztof Palczewski; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3915.

ARVO Annual Meeting Abstract June 2024

Pharmacological treatment for maculopathies based on oral administration of a new visual cycle modulator

Marco Bassetto; Jianye Zhang; Gregory Tochtrop; Krzysztof Palczewski; Philip David Kiser

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3149.

ARVO Annual Meeting Abstract June 2024

Membrane frizzled-related protein determines subcellular localization of its binding partners in the apical membrane of retinal pigment epithelium cells

Aleksander Tworak; Roman Smidak; Carolline Rodrigues Menezes; Zhiqian Dong; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6748.

ARVO Annual Meeting Abstract June 2024

Fluorescent reporter cell lines for genome editing protein delivery

Rafal Holubowicz; Roman Smidak; Samuel W. Du; Alexander Yan; Marco Bassetto; Grazyna Palczewska; David Salom; Paul Z. Chen; Gregory A. Newby; Philip David Kiser; David R. Liu; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6099.

ARVO Annual Meeting Abstract June 2024

Megabody and Nanobody: antibody fragments developed for the treatment of Rhodopsin-associated autosomal dominant retinitis pigmentosa

Arum Wu; David Salom; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6079.

ARVO Annual Meeting Abstract June 2024

Stress Resilience-Enhancing Drugs: Updates on a new class of small-molecule therapies to preserve vision

Jennings Luu; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3308.

ARVO Annual Meeting Abstract June 2023

Pharmacological reduction of ceramides increases levels of long-chain polyunsaturated fatty acids in the mouse retina

Dominik Lewandowski; Fangyuan Gao; Yoshikazu Imanishi; Sanae Imanishi; Aleksander Tworak; Marco Bassetto; Zhiqian Dong; Philip David Kiser; Dorota Skowronska-Krawczyk; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5455.

ARVO Annual Meeting Abstract June 2023

Cell-specific roles of CRALBP in visual chromophore production and photoreceptor function revealed through conditional knockout mouse studies

Philip David Kiser; Marco Bassetto; Alexander V Kolesnikov; Maximilian Halabi; David Einstein; Jianying Kiser; Krzysztof Palczewski; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5196.

ARVO Annual Meeting Abstract June 2023

Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

Jennings Luu; Aicha Saadane; Henri Leinonen; Elliot Choi; Fangyuan Gao; Dominik Lewandowski; Maximilian Halabi; Arum Wu; Zhiqian Dong; Grazyna Palczewska; Robert Mullins; Neal S Peachey; Philip David Kiser; Marcin Tabaka; Timothy S Kern; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2417.

ARVO Annual Meeting Abstract June 2023

Structure-guided GPCR drug development of human single domain camelid antibodies (Nanobody) for autosomal dominant retinitis pigmentosa

Arum Wu; David Salom; John Hong; Els Pardon; Jan Steyaert; Philip David Kiser; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):765.

ARVO Annual Meeting Abstract June 2023

Characterization of G90D and G90V rhodopsin mutations causing retinal dysfunction

Alexander V Kolesnikov; Feifei Wang; Rajan Deep Adhikari; David Salom; Krzysztof Palczewski; Clint L Makino; Pere Garriga; Vladimir J. Kefalov

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1653.

ARVO Annual Meeting Abstract June 2023

Capturing Opsin Photochemistry and Chromophore Hydrolysis

John Hong; David Salom; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4471.

Visual Neuroscience July 2022

Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice

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Alexander V. Kolesnikov; Jennings Luu; Hui Jin; Krzysztof Palczewski; Vladimir J. Kefalov
TAGS: mice, retinal degeneration, protein phosphatase, retina, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):18. https://doi.org/10.1167/iovs.63.8.18

ARVO Annual Meeting Abstract June 2022

Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers

Grazyna Palczewska; Jakub Boguslawski; Michal Dabrowski; Dorota stachowiak; Grzegorz Sobon; Krzysztof Palczewski; Maciej Wojtkowski

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4448 – F0127.

ARVO Annual Meeting Abstract June 2022

Absence of PP2A accelerates retinal degeneration in GRK1- and Arr1-deficient mice

Jennings Luu; Alexander Kolesnikov; Hui Jin; Krzysztof Palczewski; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2498 – F0205.

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Eye on Genome Editing

Knocking down liver transthyretin (TTR) via RNAi leads to decreased A2E in the eyes of Abca4 -/- Rdh8 -/- mice, a model of Stargardt disease

Exploring the role of Adiponectin Receptor 1 in the dynamics of omega-3 fatty acid metabolism

Role of O -glycosylation at the N-terminus of green and red cone opsins

Efficient and therapeutic RPE prime editing via novel engineered virus-like particles

Modulation of mouse rod function by a llama-derived transducin nanobody

Pharmacological treatment for maculopathies based on oral administration of a new visual cycle modulator

Membrane frizzled-related protein determines subcellular localization of its binding partners in the apical membrane of retinal pigment epithelium cells

Fluorescent reporter cell lines for genome editing protein delivery

Megabody and Nanobody: antibody fragments developed for the treatment of Rhodopsin-associated autosomal dominant retinitis pigmentosa

Stress Resilience-Enhancing Drugs: Updates on a new class of small-molecule therapies to preserve vision

Pharmacological reduction of ceramides increases levels of long-chain polyunsaturated fatty acids in the mouse retina

Cell-specific roles of CRALBP in visual chromophore production and photoreceptor function revealed through conditional knockout mouse studies

Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

Structure-guided GPCR drug development of human single domain camelid antibodies (Nanobody) for autosomal dominant retinitis pigmentosa

Characterization of G90D and G90V rhodopsin mutations causing retinal dysfunction

Capturing Opsin Photochemistry and Chromophore Hydrolysis

Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice

Two-photon excited scanning laser ophthalmoscope enables fundus imaging in healthy volunteers

Absence of PP2A accelerates retinal degeneration in GRK1- and Arr1-deficient mice

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