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ARVO Annual Meeting Abstract June 2024

Comparison of incidence of cataracts following two different subretinal injection methods in mice

Adam Moser; Paul Miller; T Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):804.

ARVO Annual Meeting Abstract June 2024

Tolerability and Expression of an AAV8-GFP vector after Intravitreal and Subretinal Administration in Göttingen Minipigs and Cynomolgus Monkeys, with and without Immunosuppression

Peter Sonnentag; T Michael Nork; Hugh Wabers; Paul Miller; Carol A Rasmussen; Christopher J Murphy; Oliver Turner; Jayson Chen; Helen Booler

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5313.

ARVO Annual Meeting Abstract June 2023

Spontaneous retinoblastoma-like mass in the retina of a young cynomolgus macaque

Peter Sonnentag; Paul Miller; T Michael Nork; James N Ver Hoeve; Carol Rasmussen; Alex Katz; Hugh Wabers; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1267.

ARVO Annual Meeting Abstract June 2023

Characterization of Unique Bilateral Optic Atrophy in a Cynomolgus Macaque

Aileen Rowland; Paul Miller; Alex Katz; Hugh Wabers; Charlene BY Kim; Carol Rasmussen; Ken Waller; Peter Sonnentag; James N Ver Hoeve; T. Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4691.

ARVO Annual Meeting Abstract June 2022

Incidental finding of white dots in the central retinas of two young cynomolgus macaques

Peter Sonnentag; Carol A Rasmussen; Yelena Krakova; Paul Miller; Charlene B Y Kim; James N Ver Hoeve; Hugh D. Wabers; Rui Chen; Christopher J Murphy; T Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4420 – F0099.

ARVO Annual Meeting Abstract June 2021

Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbits

Vladimir Bantseev; Sara Parker; Roxanne Andaya; Chris Schuetz; Brian Christian; Paul E Miller; Helen Booler; Melissa Schutten

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):201.

Physiology and Pharmacology October 2019

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

PDF

Evan A. Thackaberry; Yi Zhou; Christina L. Zuch de Zafra; Germaine Fuh; Chingwei V. Lee; Sarah Sanowar; John B. Ridgway; Aija M. Kusi; Cindy Farman; Helen Booler; Daniel Sheinson; Carol A. Rasmussen; Paul E. Miller; Eric Wakshull; Minhong Yan; Vladimir Bantseev
TAGS: antibodies, anti-vascular endothelial growth factor therapy, aqueous humor, eye, glaucoma, intraocular pressure, macaca fascicularis, primates, signal transduction, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4097-4108. https://doi.org/10.1167/iovs.18-26349

ARVO Annual Meeting Abstract July 2019

Chronic Nonclinical Ocular Toxicity Study of KSI-301 Demonstrates Tolerability after Intravitreal Administration in Cynomolgus Monkeys

John Sinclair; hong liang; zachary antonio; paul miller; avery tolosa; joel naor; leah quarberg; alok sharma; Xiaojian Huang; Janine Lu; William Ngo; dan dang; frances clemo; James N Ver Hoeve; T. Michael Nork; D. Victor Perlroth

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):126.

ARVO Annual Meeting Abstract July 2018

Ocular Safety of AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) following intravitreous injection and exposure to 595 nm LED light in blind rd1 mice

Brian J Christian; Steven D Sorden; Michael Ward; T Michael Nork; Paul E Miller; Anne Douar; Nitza Thomasson; Celine Bouquet

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5658.

ARVO Annual Meeting Abstract July 2018

Development of Minipigs Surgical Model: Cauterization of the Choroid Following Scleral Dissection Mitigates Risk of Post-Operative Vitreous Hemorrhage Following Ocular Implantation of RPDS

Vladimir Bantseev; Giulio Barteselli; Chris Schuetz; Josh Horvath; Kristof Hovaten; Signe R Erickson; Jay M Stewart; Ellison Bentley; Paul E Miller; Brittney Dwyer; Jeffery J Prusakiewicz; T Michael Nork; Helen S Booler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5929.

ARVO Annual Meeting Abstract July 2018

In vivo Effects of CCFD9260S Following Intravitreal Administration to Cynomolgus Monkeys

Helen S Booler; Nardos Tassew; Aija MacKenzie; Hong Liu; Deborah O'Connor; Florence Lorget; Paul E Miller; Tim Streit; T Michael Nork; James N Ver Hoeve; Cinzia Stella; Yanqiu Liu; Daniela Bumbaca; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):80.

Physiology and Pharmacology August 2017

Evaluation of the Toxicity of Intravitreally Injected PLGA Microspheres and Rods in Monkeys and Rabbits: Effects of Depot Size on Inflammatory Response

PDF

Evan A. Thackaberry; Cindy Farman; Fiona Zhong; Florence Lorget; Karin Staflin; Angelique Cercillieux; Paul E. Miller; Chris Schuetz; Debby Chang; Amin Famili; Ann L. Daugherty; Karthik Rajagopal; Vladimir Bantseev
TAGS: microspheres, oryctolagus cuniculus, rod photoreceptors, toxic effect, inflammatory response
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4274-4285. https://doi.org/10.1167/iovs.16-21334

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Retinal Glutamate Upregulation in Chronic Experimental Glaucoma (EG) with or without Prior Hemiretinal Endodiathermy Axotomy (HEA)

Alexander Katz; Charlene B Y Kim; Hau Nguyen; Vijaykrishna Raghunathan; Paul Russell; Paul Miller; Christopher J Murphy; Brian J Christian; T Michael Nork

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2557.

ARVO Annual Meeting Abstract June 2017

Dynamic compensation occurs in the aqueous outflow pathway in non-human primates with experimental glaucoma

Seth Eaton; Vijaykrishna Raghunathan; Brian J Christian; Joshua T Morgan; James N Ver Hoeve; Chen-Yuan Charlie Yang; Haiyan Gong; Carol A Rasmussen; Paul Miller; Paul Russell; T Michael Nork; Christopher J Murphy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3148.

ARVO Annual Meeting Abstract June 2017

Characterization of a Rabbit Model of Choroidal Neovascularization (CNV) and its Treatment with Lucentis®

Craig B Struble; Megan Krueger; Carol Rasmussen; Anne Goulding; Mike Neider; Hugh Wabers; Paul Miller; Ismail Zaitoun; Nadar Sheibani; Steve Van Adestine; Alok Sharma; mike Nork

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4076.

ARVO Annual Meeting Abstract June 2017

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Cynomolgus Macaques

Brian J Christian; Paul Miller; T Michael Nork; Carol A Rasmussen; Thomas Larsen; Evan A Thackaberry; Helen Booler; Vladimir Bantseev

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5164.

Anatomy and Pathology/Oncology March 2017

Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbits

PDF

Vladimir Bantseev; Paul E. Miller; Ellison Bentley; Chris Schuetz; Tim M. Streit; Brian J. Christian; Cindy Farman; Helen Booler; Evan A. Thackaberry
TAGS: dutch, endotoxins, eye, intravitreal injections, no-observed-effect level, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1545-1552. https://doi.org/10.1167/iovs.16-21356

ARVO Annual Meeting Abstract September 2016

Upregulation of Retinal Glutamate in Chronic Experimental Glaucoma

T Michael Nork; Hau Nguyen; Alexander Katz; Ying Ge; Charlene B Y Kim; Vijaykrishna Raghunathan; Paul Russell; Paul Miller; Christopher J Murphy; Brian J Christian

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2573.

ARVO Annual Meeting Abstract September 2016

A 6-Week Toxicity and Toxicokinetics Study of a Single Bilateral Intracameral Administration of ENV905 (difluprednate) Ophthalmic Implant in New Zealand White Rabbits

RiLee Robeson; Rozemarijn S Verhoeven; Andres Garcia; Paul Miller; Jacqueline Miller; Tomas Navratil; Rhett M Schiffman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4013.

Vision Sciences Society Annual Meeting Abstract September 2015

Reducing the size of the human blind spot through training.

Paul Miller; Derek Arnold

Journal of Vision. 2015; 15(12):1300. https://doi.org/10.1167/15.12.1300

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Comparison of incidence of cataracts following two different subretinal injection methods in mice

Tolerability and Expression of an AAV8-GFP vector after Intravitreal and Subretinal Administration in Göttingen Minipigs and Cynomolgus Monkeys, with and without Immunosuppression

Spontaneous retinoblastoma-like mass in the retina of a young cynomolgus macaque

Characterization of Unique Bilateral Optic Atrophy in a Cynomolgus Macaque

Incidental finding of white dots in the central retinas of two young cynomolgus macaques

Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbits

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

Chronic Nonclinical Ocular Toxicity Study of KSI-301 Demonstrates Tolerability after Intravitreal Administration in Cynomolgus Monkeys

Ocular Safety of AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) following intravitreous injection and exposure to 595 nm LED light in blind rd1 mice

Development of Minipigs Surgical Model: Cauterization of the Choroid Following Scleral Dissection Mitigates Risk of Post-Operative Vitreous Hemorrhage Following Ocular Implantation of RPDS

In vivo Effects of CCFD9260S Following Intravitreal Administration to Cynomolgus Monkeys

Evaluation of the Toxicity of Intravitreally Injected PLGA Microspheres and Rods in Monkeys and Rabbits: Effects of Depot Size on Inflammatory Response

Retinal Glutamate Upregulation in Chronic Experimental Glaucoma (EG) with or without Prior Hemiretinal Endodiathermy Axotomy (HEA)

Dynamic compensation occurs in the aqueous outflow pathway in non-human primates with experimental glaucoma

Characterization of a Rabbit Model of Choroidal Neovascularization (CNV) and its Treatment with Lucentis®

Determination of a No Observable Effect Level (NOEL) for Endotoxin following a Single Intravitreal Administration to Cynomolgus Macaques

Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbits

Upregulation of Retinal Glutamate in Chronic Experimental Glaucoma

A 6-Week Toxicity and Toxicokinetics Study of a Single Bilateral Intracameral Administration of ENV905 (difluprednate) Ophthalmic Implant in New Zealand White Rabbits

Reducing the size of the human blind spot through training.

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