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Retina June 2025

Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment

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Rui Ji; Keijiro Ishikawa; Wei Tan; Kenichiro Mori; Ryotaro Tsukamoto; Naoya Matsunaga; Kohei Kiyohara; Yosuke Fukuda; Iori Wada; Tomoyuki Isobe; Tomohito Tanihara; Yuya Yoshida; Kouta Mayanagi; Kosuke Oyama; Yuma Terada; Kaita Otsuki; Kengo Hamamura; Hiroshi Kikuchi; Shintaro Nakao; Shigeo Yoshida; Ram Kannan; Shigehiro Ohdo; Koh-Hei Sonoda
TAGS: encapsulation, hmga2 protein, lipoma, liposomes, radioimmunoprecipitation assay, ristocetin induced platelet aggregation, vitreoretinal disease, fibrosis, choroidal neovascularization, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):56. https://doi.org/10.1167/iovs.66.6.56

Includes: Supplemental Content

Glaucoma June 2025

PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade

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Yumeng Zhang; Hanwen Huang; Huimin Zhong; Yang Zhang; Siqi He; Yanzhi Guo; Yiwei Wang; Ping Huang; Shouyue Huang; Yisheng Zhong
TAGS: aging, mice, older adult, signal transduction, retinal ganglion cells, western blotting, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):8. https://doi.org/10.1167/iovs.66.6.8

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2025

Validation of Four Prognostic Models for Metastatic Posterior Uveal Melanoma in a Danish Cohort

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Tine Gadegaard Hindso; Camilla Wium Bjerrum; Kristoffer Nissen; Mette Bagger Sjøl; Carsten Faber; Steffen Heegaard; Karine Madsen; Susanne Rosthøj; Jens Folke Kiilgaard
TAGS: cohort studies, danish, nomogram, patient prognosis, uveal melanoma, calibration
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):38. https://doi.org/10.1167/iovs.66.5.38

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2025

SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma

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Jiahe Nie; Junjie Tang; Zhihui Zhang; Hetian Sun; Xinyue Wang; Longxiang Wang; Meng Wang; Weifeng Huang; Yang Gao; Jinmiao Li; Chao Cheng; Shicai Su; Shuxia Chen; Siming Ai; Yuxiang Mao; Ping Zhang; Yaoming Liu; Rong Lu
TAGS: oncogenes, retinoblastoma, tumor cell invasion, genes, cell lines, transplantation, heterologous
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):24. https://doi.org/10.1167/iovs.66.5.24

Includes: Supplemental Content

Cornea & External Disease April 2025

A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing

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Mark Dibbs; Mitchelle Matesva; Despoina Theotoka; Christina Jayaraj; Beruk Metiku; Patrick Demkowicz; Jacob S. Heng; Yvonne Wang; Christine Y. Bakhoum; Jessica Chow; Mathieu F. Bakhoum
TAGS: bacteria, corneal ulcer, nanopore sequencing, pathogenic organism, ulcer, eye, cornea
Trans. Vis. Sci. Tech.. 2025; 14(4):19. https://doi.org/10.1167/tvst.14.4.19

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract April 2025

Poster Session: The effect of fixational eye-movements on the temporal summation at detection threshold: A simulation study

Zahra M. Bagheri; Allie C. Schneider; Mengxin Wang; David H. Brainard; Hannah E. Smithson
TAGS: eye movement, posters, temporal summation
Journal of Vision. 2025; 25(5):24. https://doi.org/10.1167/jov.25.5.24

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks I: Fixational eye movements and retinal adaptation: optimizing drift to maximize information acquisition

Daniel J. Read; Alexander J. H. Houston; Hannah E. Smithson; David H. Brainard; Allie C. Hexley; Mengxin Wang
TAGS: eye movement
Journal of Vision. 2025; 25(5):9. https://doi.org/10.1167/jov.25.5.9

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks I: The role of fixational drift in the Vernier task

Fabian Coupette; David H. Brainard; Hannah E. Smithson; Daniel J. Read
TAGS: blurry vision, diffusion, eye, eye movement, medical history, motion, noise, perception, persistence, recovery of function
Journal of Vision. 2025; 25(5):8. https://doi.org/10.1167/jov.25.5.8

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks I: Detecting and characterising microsaccades from AOSLO images of the photoreceptor mosaic using computer vision

Maria Villamil; Allie C. Schneider; Jiahe Cui; Laura K. Young; Hannah E. Smithson
TAGS: computer vision systems, mosaic trial, mosaicism, photoreceptors
Journal of Vision. 2025; 25(5):5. https://doi.org/10.1167/jov.25.5.5

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks I: Information integration in early visual processing revealed by Vernier thresholds

Mengxin Wang; Daniel Read; David H. Brainard; Hannah E. Smithson
TAGS: visual processing
Journal of Vision. 2025; 25(5):6. https://doi.org/10.1167/jov.25.5.6

Retina February 2025

Lamp2 Deficiency Enhances Susceptibility to Oxidative Stress–Induced RPE Degeneration

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Guannan Wu; Shoji Notomi; Ziming Xu; Yosuke Fukuda; Yusuke Maehara; Yan Tao; Huanyu Zhao; Keijiro Ishikawa; Yusuke Murakami; Toshio Hisatomi; Koh-Hei Sonoda
TAGS: lamp-2, mice, retina, tissue degeneration, disease susceptibility, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):2. https://doi.org/10.1167/iovs.66.2.2

Includes: Supplemental Content

Retina December 2024

Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema

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Kim Lien Huber; Heiko Stino; Irene Steiner; Philipp Fuchs; Felix Goldbach; Julia Mai; Bianca S. Gerendas; Katharina Kriechbaum; Ursula Schmidt-Erfurth; Andreas Pollreisz
TAGS: aflibercept, diabetic macular edema, eye, faricimab, injections, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):46. https://doi.org/10.1167/iovs.65.14.46

Includes: Supplemental Content

Perspective December 2024

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

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Ted S. Acott; Michael P. Fautsch; Weiming Mao; C. Ross Ethier; Alex S. Huang; Mary J. Kelley; Mini Aga; Sanjoy K. Bhattacharya; Terete Borras; Diane Bovenkamp; Uttio Roy Chowdhury; Abbot F. Clark; Mohammed I. Dibas; Yiqin Du; Michael H. Elliott; Jennifer A. Faralli; Haiyan Gong; Samuel Herberg; Murray A. Johnstone; Paul L. Kaufman; Kate E. Keller; Ruth A. Kelly; David Krizaj; Markus H. Kuehn; Hoi Lam Li; Raquel Lieberman; Shan C. Lin; Yutao Liu; Fiona S. McDonnell; Colleen M. McDowell; Gillian J. McLellan; Philip Mzyk; Kayarat Saidas Nair; Darryl R. Overby; Donna M. Peters; VijayKrishna Raghunathan; Ponugoti Vasantha Rao; Gavin W. Roddy; Najam A. Sharif; Myoung Sup Shim; Yang Sun; Benjamin R. Thomson; Carol B. Toris; Colin E. Willoughby; Hao F. Zhang; Thomas F. Freddo; Rudolf Fuchshofer; Kamisha R. Hill; Alireza Karimi; Krishnakumar Kizhatil; Casey C. Kopcyznski; Paloma Liton; Gaurang Patel; Michael Peng; Padmanabhan P. Pattabiraman; Ganesh Prasanna; Ester Reina-Torres; E. Griffen Samples; John R. Samples; Cynthia L. Steel; Clemens A. Strohmaier; Preeti Subramanian; Chenna Kesavulu Sugali; Joseph van Batenburg-Sherwood; Cydney Wong; Hannah Youngblood; Gulab S. Zode; Elizabeth White; W. Daniel Stamer
TAGS: body tissue, eye, fluid flow, intraocular pressure, perfusion, regulation, organ culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):32. https://doi.org/10.1167/iovs.65.14.32

Neuro-ophthalmology December 2024

Objective Visual Acuity Estimates in Amblyopia Are More Accurate With Optotype-Based P300 Than With VEP Measurements

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Akshara V. Gopiswaminathan; Julia Haldina; Khaldoon O. Al-Nosairy; Céline Z. Duval; Francie H. Stolle; Michael B. Hoffmann; Sven P. Heinrich
TAGS: amblyopia, evoked potentials, visual, visual acuity, eye
Trans. Vis. Sci. Tech.. 2024; 13(12):30. https://doi.org/10.1167/tvst.13.12.30

Includes: Supplemental Content

Retina November 2024

Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole

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Madeline E. Olufsen; Jens Hannibal; Nina B. Sørensen; Anders T. Christiansen; Ulrik C. Christensen; Grazia Pertile; David H. Steel; Steffen Heegaard; Jens F. Kiilgaard
TAGS: amnion, retinal perforations, suidae, transplantation, follow-up, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):52. https://doi.org/10.1167/iovs.65.13.52

Includes: Supplemental Content

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Letters to the Editor November 2024

Flexible Relations Between Confidence and Confidence RTs in Post-Decisional Models of Confidence: A Reply to Chen and Rahnev

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Stef Herregods; Luc Vermeylen; Kobe Desender
TAGS: calr gene, cardiac resynchronization therapy, datasets, decision making, radiochemotherapy, reaction time, recovery of function, judgment, seizures
Journal of Vision. 2024; 24(12):9. https://doi.org/10.1167/jov.24.12.9

Retina November 2024

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

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Jacqueline Fröhlich; Marco Cattaneo; Philippe Valmaggia; Peter M. Maloca; Konstantin Gugleta; Leopold Schmetterer; Hendrik P.N. Scholl; Giacomo Calzetti
TAGS: laser speckle contrast imaging, optic disk, perfusion, vascular flow, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(11):8. https://doi.org/10.1167/tvst.13.11.8

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Multiple-Object-Tracking Supported by Parvocellular, Magnocellular, and Koniocellular Pathways

Linan Shi; Yunjie Song; Sheng He

Journal of Vision. 2024; 24(10):822. https://doi.org/10.1167/jov.24.10.822

Vision Sciences Society Annual Meeting Abstract September 2024

You see first what you like most: Visually prioritizing positive over negative semantic stimuli

Sihan He; Jay Pratt

Journal of Vision. 2024; 24(10):616. https://doi.org/10.1167/jov.24.10.616

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Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment

PRMT5 Regulates Senescence in Retinal Ganglion Cells by Targeting the Wnt/β-Catenin Signaling Cascade

Validation of Four Prognostic Models for Metastatic Posterior Uveal Melanoma in a Danish Cohort

SOX4 as a Key Oncogene Driving Tumor Invasion in Retinoblastoma

A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing

Poster Session: The effect of fixational eye-movements on the temporal summation at detection threshold: A simulation study

Contributed Talks I: Fixational eye movements and retinal adaptation: optimizing drift to maximize information acquisition

Contributed Talks I: The role of fixational drift in the Vernier task

Contributed Talks I: Detecting and characterising microsaccades from AOSLO images of the photoreceptor mosaic using computer vision

Contributed Talks I: Information integration in early visual processing revealed by Vernier thresholds

Lamp2 Deficiency Enhances Susceptibility to Oxidative Stress–Induced RPE Degeneration

Real-World Outcomes After Switch From Aflibercept to Faricimab in Eyes With Diabetic Macular Edema

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches

Objective Visual Acuity Estimates in Amblyopia Are More Accurate With Optotype-Based P300 Than With VEP Measurements

Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Flexible Relations Between Confidence and Confidence RTs in Post-Decisional Models of Confidence: A Reply to Chen and Rahnev

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

Multiple-Object-Tracking Supported by Parvocellular, Magnocellular, and Koniocellular Pathways

You see first what you like most: Visually prioritizing positive over negative semantic stimuli

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