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ARVO Annual Meeting Abstract June 2024

Fluorescence lifetime imaging of aged murine lacrimal glands shows multiple metabolic changes

Jason Junge; Minchang Choi; Cindy Toscano; Maria Edman; Cintia S De Paiva; Sarah Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6589.

ARVO Annual Meeting Abstract June 2024

Thermosensitive elastin-like polypeptides bind pro-inflammatory IL-17A and form local depots following supra-lacrimal injection

Shin-Jae Lee; Sara Abdelhamid; Quratulain Bhatti; Maria Edman; Sarah F Hamm-Alvarez; J. Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4594.

Physiology and Pharmacology June 2024

The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation

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Minchang Choi; Cindy Toscano; Maria C. Edman; Cintia S. de Paiva; Sarah F. Hamm-Alvarez
TAGS: aging, langer-giedion syndrome, lipids, macrophages, mice, niemann-pick disease, type c, mice, inbred c57bl, proteins, fluorescent antibody technique, lacrimal gland
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):1. https://doi.org/10.1167/iovs.65.6.1

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2023

Evidence for lipid dysregulation associated with inflammation in lacrimal glands from aged female C57BL/6J mice

Minchang Choi; Cindy Toscano; Maria Edman; Sarah F Hamm-Alvarez; Cintia S. De Paiva

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):695.

Immunology and Microbiology April 2023

The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis

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Shruti Singh Kakan; Xiaoyang Li; Maria C. Edman; Curtis T. Okamoto; Brooke E. Hjelm; Sarah F. Hamm-Alvarez
TAGS: dacryoadenitis, mice, micrornas, autoimmunity, sjogren's syndrome, mice, inbred nod, lacrimal gland
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):1. https://doi.org/10.1167/iovs.64.4.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Identification of miRNAs in tears of a murine model of Sjögren’s syndrome that may represent putative diagnostic biomarkers

Shruti Singh Kakan; Maria Edman; Brooke Erika Hjelm; Curtis T Okamoto; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3473.

ARVO Annual Meeting Abstract June 2021

Changes in expression of regulators of protein phosphatase 2A are observed in lacrimal gland from a murine model of Sjögren’s syndrome

Minchang Choi; Hao Guo; Maria Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3467.

Articles July 2020

Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption

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Hossein Ameri; Christopher Murat; Amirmohsen Arbabi; Wei Jiang; Srikanth R. Janga; Peter Zhifeng Qin; Sarah F. Hamm-Alvarez
TAGS: crispr-cas9, genes, radial retinal glial cell, vascular endothelial growth factor a, retinal pigment cell, ribonucleoproteins
Trans. Vis. Sci. Tech.. 2020; 9(8):23. https://doi.org/10.1167/tvst.9.8.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Intralacrimal Delivery of Rapa Shows Therapeutic Effects Without Systemic Toxicity in NOD Mice

Yaping Ju; Maria Edman; Hao Guo; Srikanth Reddy Janga; Santosh Peddi; J.Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):144.

ARVO Annual Meeting Abstract June 2020

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model

Runzhong Fu; Hao Guo; Srikanth Reddy Janga; Minchang Choi; Wannita Klinngam; Maria Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1963.

ARVO Annual Meeting Abstract July 2019

Multivalent Lacripep Elastin-Like Polypeptide fusions initiate calcium signaling and prosecretory activity in cells of the ocular surface system

Changrim Lee; Maria Edman; Sarah F Hamm-Alvarez; John Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):308.

ARVO Annual Meeting Abstract July 2019

Development of a targeted carrier for Rapamycin in a murine model of Sjögren’s syndrome

Yaping Ju; Hao Guo; Frances Yarber; Maria Edman; Santosh Peddi; Srikanth Reddy Janga; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2822.

ARVO Annual Meeting Abstract July 2019

Tear biomarkers for Sjögren Syndrome

Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3287.

ARVO Annual Meeting Abstract July 2019

The α 1 -adrenergic agonist, phenylephrine, increases tear cathepsin S secretion through a Rab27a-independent pathway

Runzhong Fu; Srikanth Reddy Janga; Maria Edman; Frances Yarber; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4195.

ARVO Annual Meeting Abstract July 2019

Tear biomarkers for Parkinson’s disease in basal versus reflex tears

Maria C Edman; Srikanth Reddy Janga; Daniel Freire; Danielle Feigenbaum; Wendy Mack; Curtis T Okamoto; Mark F Lew; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4196.

ARVO Annual Meeting Abstract July 2019

Analysis of CD4+ T cell populations in male NOD mice highlights the potential of local administration of cyclosporine A in the treatment of Sjögren’s syndrome

Hao Guo; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):279.

ARVO Annual Meeting Abstract July 2018

Atrophy and Impaired Contraction of the Myoepithelial Cells in Lacrimal Glands of Sjögren’s Syndrome Animal Models of Dry Eye Disease

Driss Zoukhri; Dillon Hawley; Xin Tang; Tatiana Zyrianova; Mihir Shah; Srikanth Reddy Janga; Alexandra Letourneau; Martin Schicht; Friedrich P Paulsen; Sarah Hamm-Alvarez; Helen P Makarenkova

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2286.

ARVO Annual Meeting Abstract July 2018

Cathepsin S Inhibitor Reduces Lacrimal Gland Inflammation and Increases Tear Flow In a Mouse Model of Sjögren’s Syndrome

Wannita Klinngam; Srikanth Reddy Janga; Maria C. Edman; Mihir Shah; Frances Yarber; Hao Guo; Benjamin Cooperman; Dandan Wang; Sarah Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2672.

ARVO Annual Meeting Abstract July 2018

Tear Proteins as Possible Biomarkers for Parkinson’s Disease

Sarah F Hamm-Alvarez; Mark Lew; Danielle Feigenbaum; Srikanth Reddy Janga; Mihir Shah; Daniel Freire; Benjamin Cooperman; Raveena Ghanshani; Wendy Mack; Curtis Okamoto

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4909.

ARVO Annual Meeting Abstract July 2018

Elastin-like polypeptide mediate subcutaneous delivery of Rapamycin in a murine model of Sjögren’s Syndrome

Changrim Lee; Hao Guo; Wannita Klinngam; Srikanth Reddy Janga; Frances Yarber; Maria C. Edman; Santosh Peddi; Sarah F Hamm-Alvarez; J. Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5677.

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Fluorescence lifetime imaging of aged murine lacrimal glands shows multiple metabolic changes

Thermosensitive elastin-like polypeptides bind pro-inflammatory IL-17A and form local depots following supra-lacrimal injection

The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation

Evidence for lipid dysregulation associated with inflammation in lacrimal glands from aged female C57BL/6J mice

The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis

Identification of miRNAs in tears of a murine model of Sjögren’s syndrome that may represent putative diagnostic biomarkers

Changes in expression of regulators of protein phosphatase 2A are observed in lacrimal gland from a murine model of Sjögren’s syndrome

Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption

Intralacrimal Delivery of Rapa Shows Therapeutic Effects Without Systemic Toxicity in NOD Mice

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model

Multivalent Lacripep Elastin-Like Polypeptide fusions initiate calcium signaling and prosecretory activity in cells of the ocular surface system

Development of a targeted carrier for Rapamycin in a murine model of Sjögren’s syndrome

Tear biomarkers for Sjögren Syndrome

The α 1 -adrenergic agonist, phenylephrine, increases tear cathepsin S secretion through a Rab27a-independent pathway

Tear biomarkers for Parkinson’s disease in basal versus reflex tears

Analysis of CD4+ T cell populations in male NOD mice highlights the potential of local administration of cyclosporine A in the treatment of Sjögren’s syndrome

Atrophy and Impaired Contraction of the Myoepithelial Cells in Lacrimal Glands of Sjögren’s Syndrome Animal Models of Dry Eye Disease

Cathepsin S Inhibitor Reduces Lacrimal Gland Inflammation and Increases Tear Flow In a Mouse Model of Sjögren’s Syndrome

Tear Proteins as Possible Biomarkers for Parkinson’s Disease

Elastin-like polypeptide mediate subcutaneous delivery of Rapamycin in a murine model of Sjögren’s Syndrome

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