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Cornea June 2025

Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice

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Ning Wang; Yizhou Li; Xiaolei Wang; Lingling Yang; Jing Zhang; Jun Cheng; Xiaoyue Jiang; Xia Qi; Chao Wei; Qingjun Zhou; Ya Li; Suxia Li

Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):28. https://doi.org/10.1167/iovs.66.6.28

Includes: Supplemental Content

Cornea June 2025

SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction

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Yizhou Li; Feijia Xie; Lingling Yang; Xiaolei Wang; Yangyang Zhang; Hongqi Ge; Min Wang; Rui Cao; Qingjun Zhou; Ya Li
TAGS: cornea, epithelium, mice, stem cells, taurine, wound healing, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):25. https://doi.org/10.1167/iovs.66.6.25

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology June 2025

Impact of Optic Nerve Tortuosity, Globe Proptosis, and Size on Retinal Ganglion Cell Thickness Across General, Glaucoma, and Myopic Populations

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Charis Y. N. Chiang; Xiaofei Wang; Stuart K. Gardiner; Martin Buist; Michaël J. A. Girard
TAGS: exophthalmos, eye, glaucoma, optic nerve, orbit, retinal ganglion cells, retinal nerve fiber layer, magnetic resonance imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):4. https://doi.org/10.1167/iovs.66.6.4

Includes: Supplemental Content

Glaucoma June 2025

Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery

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Phey Feng Lo; Merry Gunawan; Zhu Li Yap; Carol Leong; Fuxuan Kwek; Jayasudha Varadarajan; Xiaomeng Wang; Masaaki Kageyama; Tina T. Wong
TAGS: blister, surgical procedures, operative, valproic acid, fibrosis, surgical procedures, minimally invasive, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2025; 14(6):6. https://doi.org/10.1167/tvst.14.6.6

Includes: Supplemental Content

Lens May 2025

PERK Regulates Epithelial–Mesenchymal Transition Through Autophagy and Lipid Metabolism in Lens Epithelial Cells

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Xiaoran Wang; Baoxin Chen; Jieping Chen; Mi Huang; Shan Huang
TAGS: autophagy, endoplasmic reticulum stress, epithelial to mesenchymal transition, epithelium, fibrosis, lens (device), lens epithelial cell, lens, crystalline, fat metabolism, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):35. https://doi.org/10.1167/iovs.66.5.35

Includes: Supplemental Content

Cornea May 2025

Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye

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Runze Zhang; Lihong Liang; Kai Liao; Hao Zeng; Xue Yang; Xiaoran Wang; Bowen Wang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, stress, autophagy, western blotting, impairment
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):23. https://doi.org/10.1167/iovs.66.5.23

Includes: Supplemental Content

Cornea April 2025

Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells

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Min Wang; Rong Chen; Yao Wang; Ya Li; Qingjun Zhou; Rui Cao; Yizhou Li; Hongqi Ge; Xiaolei Wang; Lingling Yang
TAGS: cornea, keratins, limbal stem cells, proteins, stress, epithelium, mice, corneal epithelium, rna, messenger, rna-seq
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):55. https://doi.org/10.1167/iovs.66.4.55

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2025

Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk

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Wei-Qi Song; Wen-Fang Zhong; Zhi-Hao Li; Dan Liu; Jiao-Jiao Ren; Dong Shen; Jian Gao; Pei-Liang Chen; Jin Yang; Xiao-Meng Wang; Fang-Fei You; Chuan Li; Huan Chen; Jia-Hao Xie; Chen Mao
TAGS: glaucoma, genetic predisposition to disease
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):47. https://doi.org/10.1167/iovs.66.4.47

Includes: Supplemental Content

Immunology and Microbiology April 2025

Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren’s Syndrome Related Dry Eye

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Bowen Wang; Lihong Liang; Hao Zeng; Xue Yang; Runze Zhang; Wenrui Deng; Xiaoran Wang; Jin Yuan
TAGS: conjunctiva, dry eye syndromes, keratinocytes, sequence analysis, rna, signal transduction, sjogren's syndrome, rna, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):43. https://doi.org/10.1167/iovs.66.4.43

Includes: Supplemental Content

Retina February 2025

Photoreceptor Function and Structure in Retinal Areas With Intraretinal Hyperreflective Foci in Age-Related Macular Degeneration

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Xiaolin Wang; Sujin Hoshi; Ruixue Liu; Giulia Corradetti; Michael Ip; David Sarraf; SriniVas R. Sadda; Yuhua Zhang
TAGS: age-related macular degeneration, photophobia, photoreceptors, drusen, eye, multimodal imaging, retina, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):27. https://doi.org/10.1167/iovs.66.2.27

Cornea February 2025

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

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Hao Chi; Li Ma; Fanxing Zeng; Xiaolei Wang; Peng Peng; Xiaofei Bai; Ting Zhang; Wenhui Yin; Yaoyao Yu; Lingling Yang; Qingjun Zhou; Chao Wei; Weiyun Shi
TAGS: aging, allografting, angiotensin converting enzyme 2, cornea, keratoplasty, navitoclax, rejection (psychology), senolytics, stress, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):15. https://doi.org/10.1167/iovs.66.2.15

Includes: Supplemental Content

Article December 2024

Relating visual and pictorial space: Integration of binocular disparity and motion parallax

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Xiaoye Michael Wang; Nikolaus F. Troje
TAGS: motion, perception, vision disparity, vision, boop, comprehensive observations of proprioception
Journal of Vision. 2024; 24(13):7. https://doi.org/10.1167/jov.24.13.7

Retina November 2024

Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums

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Thanadet Chuangsuwanich; Tin A. Tun; Fabian A. Braeu; Rachel S. Chong; Xiaofei Wang; Ching-Lin Ho; Tin Aung; Michaël J. A. Girard; Quan V. Hoang
TAGS: glaucoma, intraocular pressure, macula lutea, sclera, nose, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):54. https://doi.org/10.1167/iovs.65.13.54

Includes: Supplemental Content

Retinal Cell Biology November 2024

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

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Xueming Yao; Ziqi Li; Yi Lei; Qiangyun Liu; Siyue Chen; Haokun Zhang; Xue Dong; Kai He; Ju Guo; Mulin Jun Li; Xiaohong Wang; Hua Yan
TAGS: astrocytes, genes, heterogeneity, mice, multiomics, oxygen, retinal diseases, small nuclear rna, cell communication, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):8. https://doi.org/10.1167/iovs.65.13.8

Includes: Supplemental Content

Retina October 2024

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

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Ying Xiang Han; Xiao Xiao Guo; Ya Xing Wang; Jost B. Jonas; Xi Chen; Xiao Fei Wang
TAGS: sclera, staphyloma, macular disorders, eye, magnetic resonance imaging
Trans. Vis. Sci. Tech.. 2024; 13(10):41. https://doi.org/10.1167/tvst.13.10.41

Includes: Supplemental Content

Visual Neuroscience October 2024

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

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Xiaobing Wang; Mingxin Yan; Jingmin Li; Yuexin Wang
TAGS: learning, motion, perceptual learning, visual acuity testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):43. https://doi.org/10.1167/iovs.65.12.43

Cornea September 2024

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

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Yunhai Dai; Shilan Mao; Xinyi Zang; Hongqi Ge; Jing Feng; Yalin Wang; Xia Qi; Lingling Yang; Qingjun Zhou; Xiaolei Wang
TAGS: cornea, diabetes mellitus, type 2, human herpesvirus 1, infections, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):36. https://doi.org/10.1167/iovs.65.11.36

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Visual field map size predicts spatial working memory performance

Nathan Tardiff; Xingyu Ding; Xiao-Jing Wang; Clayton Curtis

Journal of Vision. 2024; 24(10):1169. https://doi.org/10.1167/jov.24.10.1169

Vision Sciences Society Annual Meeting Abstract September 2024

Addressing the Vergence-Accommodation Conflict in Virtual Reality: A Geometrical Approach

Xiaoye Michael Wang; Colin Dolynski; Michael Nitsche; Gabby Resch; Ali Mazalek; Timothy N Welsh

Journal of Vision. 2024; 24(10):627. https://doi.org/10.1167/jov.24.10.627

Glaucoma July 2024

Effect of Eye Globe and Optic Nerve Morphologies on Gaze-Induced Optic Nerve Head Deformations

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Tingting Liu; Pham Tan Hung; Xiaofei Wang; Michaël J. A. Girard
TAGS: body tissue, exertional dyspnea, eye, eye movement, gaze, optic disk, optic nerve, sclera, dura mater
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):48. https://doi.org/10.1167/iovs.65.8.48

Includes: Supplemental Content

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Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice

SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction

Impact of Optic Nerve Tortuosity, Globe Proptosis, and Size on Retinal Ganglion Cell Thickness Across General, Glaucoma, and Myopic Populations

Valproic Acid Application to Modify Post Surgical Fibrosis in a Model of Minimally Invasive Bleb Surgery

PERK Regulates Epithelial–Mesenchymal Transition Through Autophagy and Lipid Metabolism in Lens Epithelial Cells

Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye

Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells

Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk

Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren’s Syndrome Related Dry Eye

Photoreceptor Function and Structure in Retinal Areas With Intraretinal Hyperreflective Foci in Age-Related Macular Degeneration

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

Relating visual and pictorial space: Integration of binocular disparity and motion parallax

Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums

Single-Cell Multiomics Profiling Reveals Heterogeneity of Müller Cells in the Oxygen-Induced Retinopathy Model

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

The Short- and Long-Term Perceptual Learning of Clinical Dynamic Visual Acuity Test

RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus

Visual field map size predicts spatial working memory performance

Addressing the Vergence-Accommodation Conflict in Virtual Reality: A Geometrical Approach

Effect of Eye Globe and Optic Nerve Morphologies on Gaze-Induced Optic Nerve Head Deformations

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