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ARVO Annual Meeting Abstract June 2022

IL-37 prevents corneal barrier disruption by inhibiting TNF-α/CTSS signaling in primary human corneal epithelial cells under hyperosmotic stress

De-Quan Li; Yun Zhang; Jinmiao Li; Xin Chen; Stephen C Pflugfelder; Cintia S De Paiva

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1977 – A0307. doi:

ARVO Annual Meeting Abstract June 2022

Ocular Characteristics and Disease Progression in a Preclinical Model of Batten Disease

Ashley Rowe; Xin Chen; Yacine Issioui; Thomas Dong; Yuhui Hu; Steven Gray; Katherine J Wert

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2610 – F0493. doi:

ARVO Annual Meeting Abstract June 2022

Impact of indeterminant ranges around the cut-off for antibody positivity on the use of serology for trachoma monitoring

Xinyi Chen; Beatriz Munoz; Harran Mkocha; Charlotte Gaydos; Laura Dize; Thomas Quinn; Sheila K West

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2632. doi:

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. doi: https://doi.org/10.1167/iovs.63.2.12

Glaucoma August 2021

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

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Shangru Sui; Hongxia Yu; Xiangji Wang; Wenyan Wang; Xuejiao Yang; Xiaojing Pan; Qingjun Zhou; Chen Xin; Rong Du; Shen Wu; Jingxue Zhang; Qilong Cao; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cell growth, connexin 43, gap junction protein, glaucoma, medication therapy management, mice, trabecular meshwork, myoc gene, coculture techniques, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):28. doi: https://doi.org/10.1167/iovs.62.10.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Trachoma and facial cleanliness are associated with environmental factors and hygiene behaviors in Tanzania

Xinyi Chen; Beatriz Munoz; Meraf Wolle; Harran Mkocha; Sheila K West

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2624. doi:

ARVO Annual Meeting Abstract June 2021

Correlations between Spectral-Domain OCT Measurements and Visual Acuity Change after One Year Follow-up in Patients with Retinitis Pigmentosa

Kyle Fallgatter; Elizabeth Dawson; Jessica F Yang; Richard Artola; Xinguang Chen; Jinghua Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3230. doi:

ARVO Annual Meeting Abstract June 2021

Retinal nerve fiber layer thickness as a potential marker for macular atrophy in patients with retinitis pigmentosa

Richard Artola; Jessica Yang; Kyle Fallgatter; Elizabeth Dawson; Xinguang Chen; Jinghua Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3224. doi:

Articles August 2020

The Utility of Corneal Nerve Fractal Dimension Analysis in Peripheral Neuropathies of Different Etiology

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Ioannis N. Petropoulos; Abdulrahman Al-Mohammedi; Xin Chen; Maryam Ferdousi; Georgios Ponirakis; Harriet Kemp; Reena Chopra; Scott Hau; Marc Schargus; Jan Vollert; Dietrich Sturm; Tina Bharani; Christopher Kleinschnitz; Mark Stettner; Tunde Peto; Christoph Maier; Andrew S. C. Rice; Rayaz A. Malik
TAGS: cornea, fractals, neurons, peripheral neuropathy, polyneuropathy, demyelinating, inflammatory, chronic, chemotherapy-induced peripheral neuropathy, microscopy, confocal
Trans. Vis. Sci. Tech.. 2020; 9(9):43. doi: https://doi.org/10.1167/tvst.9.9.43

Cornea August 2020

Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress

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Zhao Liu; Ding Chen; Xin Chen; Fang Bian; Wenjuan Qin; Ning Gao; Yangyan Xiao; Jinmiao Li; Stephen C. Pflugfelder; De-Quan Li
TAGS: autophagy, inflammation, stress, trehalose, corneal epithelial cells, signal pathway, signal transduction pathways
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):26. doi: https://doi.org/10.1167/iovs.61.10.26

ARVO Annual Meeting Abstract June 2020

Dynamic changes in schlemm canal and trabecular meshwork during accommodation in young adults with healthy eyes and high myopic eyes: a cross-sectional cohort study.

Chen Xin; huaizhou wang; Ningli Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3436. doi:

Review April 2020

Minimally Invasive Glaucoma Surgery: What Do We Know? Where Should We Go?

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Chen Xin; Huangzhou Wang; Ningli Wang
TAGS: glaucoma surgery, intraocular pressure, surgical procedures, minimally invasive, surgical procedures, operative, glaucoma, body tissue, angiogram, aqueous humor
Trans. Vis. Sci. Tech.. 2020; 9(5):15. doi: https://doi.org/10.1167/tvst.9.5.15

Articles February 2020

Treated PDR Reveals Age-Appropriate Vision Deterioration But Distorted Retinal Organization

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Xing D. Chen; Amro Omari; Min Hwang; Leon Kwark; Natalie Dakki; Sina Farsiu; Thomas W. Gardner
TAGS: proliferative diabetic retinopathy, vision, diabetes mellitus, eye
Trans. Vis. Sci. Tech.. 2020; 9(3):3. doi: https://doi.org/10.1167/tvst.9.3.3

Includes: Supplemental Content

Articles November 2019

Association Between Arterial Blood Gas Variation and Intraocular Pressure in Healthy Subjects Exposed to Acute Short-Term Hypobaric Hypoxia

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Yuan Xie; Yiquan Yang; Ying Han; Diya Yang; Yunxiao Sun; Xinmao Wang; Anh Hong Nguyen; Yihan Chen; Jiaxin Tian; Qing Zhang; Chen Xin; Kai Cao; Huaizhou Wang; Xiaofang Liu; Guozhong Wang; Ningli Wang
TAGS: arterial blood gas, hypoxia, intraocular pressure, bicarbonates, sea level
Trans. Vis. Sci. Tech.. 2019; 8(6):22. doi: https://doi.org/10.1167/tvst.8.6.22

Articles July 2019

Patient-Reported Outcomes Reveal Impairments Not Explained by Psychophysical Testing in Patients With Regressed PDR

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Xing D. Chen; Thomas W. Gardner
TAGS: patient self-report, psychophysics, vision, visual acuity, eye, visual fields
Trans. Vis. Sci. Tech.. 2019; 8(4):11. doi: https://doi.org/10.1167/tvst.8.4.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

IL-27 Signaling Deficiency Develops Th17-enhanced Allergic Inflammation

Yun Zhang; Xin Chen; Ruzhi Deng; Wei Chi; Stephen C Pflugfelder; De-Quan Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6722. doi:

ARVO Annual Meeting Abstract July 2019

Short Ragweed Pollen Primes Macrophage Polarization toward an Alternatively Activated Phenotype via TSLP/TSLPR Signaling Pathway in Allergic Conjunctivitis

De-Quan Li; Ruzhi Deng; Xin Chen; Ning Gao; Jiaoyue Hu; Yun Zhang; Fang Bian; Stephen C Pflugfelder

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1348. doi:

ARVO Annual Meeting Abstract July 2019

IOP fluctuation in primary open angle glaucoma (POAG) receiving canaloplasty (CP) and microcatheter-assisted trabeculotomy (MAT).

Chen Xin; huaizhou wang; Peng Yin; Ningli Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5244. doi:

ARVO Annual Meeting Abstract July 2019

Retinal Vessel Diameters and Optic Disk Morphology: a population-based study

Qing Zhang; Chen Xin; YE ZHANG; CHUNYU GUO; Ningli Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5614. doi:

ARVO Annual Meeting Abstract July 2019

Microscope Real-time Video (MRTV), High- resolution OCT (HR-OCT) & Histopathology (HP) to Assess How Transcleral Micropulse Laser (TML) Affects the Sclera, Ciliary Body (CB), Muscle (CM), Secretory Epithelium (CBSE), Suprachoroidal Space (SCS) & Aqueous Outflow System

Murray A Johnstone; Shaozhen SONG; Steven Padilla; Kimika Wen; Chen Xin; Joanne C Wen; Elizabeth Martin; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2825. doi:

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IL-37 prevents corneal barrier disruption by inhibiting TNF-α/CTSS signaling in primary human corneal epithelial cells under hyperosmotic stress

Ocular Characteristics and Disease Progression in a Preclinical Model of Batten Disease

Impact of indeterminant ranges around the cut-off for antibody positivity on the use of serology for trachoma monitoring

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

Trachoma and facial cleanliness are associated with environmental factors and hygiene behaviors in Tanzania

Correlations between Spectral-Domain OCT Measurements and Visual Acuity Change after One Year Follow-up in Patients with Retinitis Pigmentosa

Retinal nerve fiber layer thickness as a potential marker for macular atrophy in patients with retinitis pigmentosa

The Utility of Corneal Nerve Fractal Dimension Analysis in Peripheral Neuropathies of Different Etiology

Trehalose Induces Autophagy Against Inflammation by Activating TFEB Signaling Pathway in Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress

Dynamic changes in schlemm canal and trabecular meshwork during accommodation in young adults with healthy eyes and high myopic eyes: a cross-sectional cohort study.

Minimally Invasive Glaucoma Surgery: What Do We Know? Where Should We Go?

Treated PDR Reveals Age-Appropriate Vision Deterioration But Distorted Retinal Organization

Association Between Arterial Blood Gas Variation and Intraocular Pressure in Healthy Subjects Exposed to Acute Short-Term Hypobaric Hypoxia

Patient-Reported Outcomes Reveal Impairments Not Explained by Psychophysical Testing in Patients With Regressed PDR

IL-27 Signaling Deficiency Develops Th17-enhanced Allergic Inflammation

Short Ragweed Pollen Primes Macrophage Polarization toward an Alternatively Activated Phenotype via TSLP/TSLPR Signaling Pathway in Allergic Conjunctivitis

IOP fluctuation in primary open angle glaucoma (POAG) receiving canaloplasty (CP) and microcatheter-assisted trabeculotomy (MAT).

Retinal Vessel Diameters and Optic Disk Morphology: a population-based study

Microscope Real-time Video (MRTV), High- resolution OCT (HR-OCT) & Histopathology (HP) to Assess How Transcleral Micropulse Laser (TML) Affects the Sclera, Ciliary Body (CB), Muscle (CM), Secretory Epithelium (CBSE), Suprachoroidal Space (SCS) & Aqueous Outflow System

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