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Anatomy and Pathology/Oncology January 2025

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

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Yanjing Huang; Chengjie He; Qiuling Hu; Zhong Liu; Xingyi Li; Wuyou Gao; Xuanwei Liang; Rongxin Chen; Zhen Mao; Xianchai Lin
TAGS: basal cell carcinoma, eyelid, genes, infiltrative basal cell carcinoma, metabolites, neoplasms, metabolic disturbance, tumor microenvironment, up-regulation (physiology), spectrometry, mass, matrix-assisted laser desorption-ionization
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):11. https://doi.org/10.1167/iovs.66.1.11

Includes: Supplemental Content

Visual Neuroscience November 2024

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

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Zhonghao Yu; Yue Guan; Tian Xia; Xuanwen Li; Mingyue Liu; Yujia Huo; Zhuowei Wang; Zhirong Liu; Yuting Luo; Wentao Yan; Lanfang Sun; Wencan Wu; Baoguo Shen; Yikui Zhang
TAGS: optic nerve, rna, rna, messenger, white matter
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):25. https://doi.org/10.1167/iovs.65.13.25

Includes: Multimedia, Supplemental Content

Cornea November 2024

Silencing METTL3 Increases HSP70 Expression and Alleviates Fibrosis in Keratocytes

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Yapeng Jing; Jun Li; Peng Hao; Shulei Xing; Xuan Li
TAGS: acute erythroblastic leukemia, cornea, fibrosis, heat-shock proteins 70, keratocytes, alkalies, burns
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):9. https://doi.org/10.1167/iovs.65.13.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Mechanism and Consequences of Intracellular C3 activation in the Retinal Pigment Epithelium in Models of Macular Degeneration

Valencia Fernandes; Li Xuan Tan; Aparna Lakkaraju

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):767.

ARVO Annual Meeting Abstract June 2024

Target-based drug repositioning safeguards RPE homeostasis and restores functional vision in Stargardt macular degeneration

Aparna Lakkaraju; Colin James Germer; Li Xuan Tan; Valencia Fernandes; Nilsa La Cunza

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1939.

ARVO Annual Meeting Abstract June 2024

RPE mitochondrial deficits and complement C3a receptor activation drive retinal degeneration in frontotemporal dementia.

an cheng; Li Xuan Tan; Aparna Lakkaraju

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2558.

ARVO Annual Meeting Abstract June 2024

Canagliflozin Attenuated p40 Gasdermin D-mediated Retinal Glia-Neuron Crosstalk and Inflammatory Cytokine Release in a Mouse Model of Retinal Vein Occlusion

jixian ma; yazhou qin; xuan liu; qiuping liu; jingming li

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1726.

ARVO Annual Meeting Abstract June 2024

NLRP1 Acts as a Negative Regulator of Retinal Ganglion Cell Pyroptosis in a Mouse Model of Retinal Vein Occlusion

Jingming Li; jixian ma; Yazhou Qin; xuan liu; Ning Gao; qiuping liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6282.

ARVO Annual Meeting Abstract June 2024

Loss of pleckstrin homology domain and leucine rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via Akt-GSK-3β-Nrf2 pathway

xuan liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):832.

ARVO Annual Meeting Abstract June 2024

Live porcine eye model studies of subretinal injection using handheld endoscopy OCT integrated injector

yaning wang; Mandeep S Singh; Kang Li; Jinglun Yu; ruizhi zuo; Xuan Liu; Jin U. Kang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5499.

Cornea June 2024

Mesenchymal Stem Cell-Derived Exosomes as Drug Carriers for Delivering miRNA-29b to Ameliorate Inflammation in Corneal Injury Via Activating Autophagy

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Jinghua Liu; Juan Gao; Ping Lu; Yuchuan Wang; Shulei Xing; Yarong Yan; Ruifang Han; Peng Hao; Xuan Li
TAGS: 1-phosphatidylinositol 3-kinase, autophagy, cornea, corneal injuries, drug carriers, exosomes, fibrosis, inflammation, mice, micrornas
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):16. https://doi.org/10.1167/iovs.65.6.16

Cornea June 2023

Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing

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Xuan Liu; Zedu Cui; Xi Chen; Yan Li; Jin Qiu; Yuke Huang; Xiao Wang; Shuilian Chen; Qian Luo; Pei Chen; Jing Zhuang; Keming Yu
TAGS: cornea, dry eye syndromes, ferroptosis, lacrimal gland, neurons
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):27. https://doi.org/10.1167/iovs.64.7.27

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2023

The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes

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Weiqi Zhong; Changjun Lan; Zhiming Gu; Qingqing Tan; Xiaoling Xiang; Hong Zhou; Xuan Liao
TAGS: eye, myopia, retina, caviidae, proteins, dimethyl sulfoxide
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):1. https://doi.org/10.1167/iovs.64.7.1

ARVO Annual Meeting Abstract June 2023

Optineurin dynamically regulates photoreceptor outer segment phagocytosis and lysosome biogenesis in the retinal pigment epithelium

Li Xuan Tan; Colin Germer; Thushara Thamban; Nilsa La Cunza; Aparna Lakkaraju

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3887.

ARVO Annual Meeting Abstract June 2023

Ceramide-mediated apical exosome release by the RPE triggers infiltration of microglia into the subretinal space in models of macular degeneration

Colin James Germer; Li Xuan Tan; Renuka M Chaphalkar; Nilsa La Cunza; Girijha Rathnasamy; Emma Iorio; Fanny Elahi; Aparna Lakkaraju

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3775.

Cornea April 2023

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

PDF

Xiao Wang; Zedu Cui; Xi Chen; Qian Luo; Zihua Jiang; Xuan Liu; Yuke Huang; Jingyi Jiang; Shuilian Chen; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: choroidal neovascularization, cxcr4 receptors, corneal neovascularization, hypoxia, cornea
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):10. https://doi.org/10.1167/iovs.64.4.10

Includes: Supplemental Content

Lacrimal Apparatus, Eyelids, Orbit February 2023

Integrated Whole-Exome and Transcriptome Sequencing Indicated Dysregulation of Cholesterol Metabolism in Eyelid Sebaceous Gland Carcinoma

PDF

Yuchuan Wang; Jun Li; Peng Hao; Jing Li; Ruifang Han; Jinyong Lin; Xuan Li
TAGS: cancer, cholesterol metabolism, exome, eyelid, sebaceous adenocarcinoma, spinal cord stimulation, genes, proteins
Trans. Vis. Sci. Tech.. 2023; 12(2):4. https://doi.org/10.1167/tvst.12.2.4

Includes: Supplemental Content

Retina October 2022

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

PDF

Shuilian Chen; Xi Chen; Ping Zhang; Shuxia Chen; Xiao Wang; Qian Luo; Zedu Cui; Yuke Huang; Linxi Wan; Xiangtao Hou; Huan Yao; Xuan Liu; Anqi He; Zihua Jiang; Jin Qiu; Yan Li; Keming Yu; Jing Zhuang
TAGS: bioinformatics, genes, retinoblastoma, neoplasms
Invest. Ophthalmol. Vis. Sci.. 2022; 63(11):28. https://doi.org/10.1167/iovs.63.11.28

Includes: Supplemental Content

Retina August 2021

Ubiquitination-Related miRNA–mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma

PDF

Xi Chen; Shuilian Chen; Zihua Jiang; Qian Gong; Danni Tang; Qian Luo; Xuan Liu; Shengyu He; Anqi He; Yihui Wu; Jin Qiu; Yan Li; Xiao Wang; Keming Yu; Jing Zhuang
TAGS: genes, micrornas, retinoblastoma, rna, messenger, ubiquitination, proton pump inhibitors, polymerase chain reaction, cell survival
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):3. https://doi.org/10.1167/iovs.62.10.3

Includes: Supplemental Content

Cornea June 2021

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol

PDF

Zhixin Jiang; Huan Zhang; Juan Gao; Hao Yu; Ruifang Han; Lin Zhu; Xi Chen; Qian Fan; Peng Hao; Liming Wang; Xuan Li
TAGS: attenuation, cornea, corneal epithelial cells, resveratrol, sars-cov-2, corneal epithelium, tmprss2 gene, cytokine, fluorescent antibody technique, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):25. https://doi.org/10.1167/iovs.62.7.25

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Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

Silencing METTL3 Increases HSP70 Expression and Alleviates Fibrosis in Keratocytes

Mechanism and Consequences of Intracellular C3 activation in the Retinal Pigment Epithelium in Models of Macular Degeneration

Target-based drug repositioning safeguards RPE homeostasis and restores functional vision in Stargardt macular degeneration

RPE mitochondrial deficits and complement C3a receptor activation drive retinal degeneration in frontotemporal dementia.

Canagliflozin Attenuated p40 Gasdermin D-mediated Retinal Glia-Neuron Crosstalk and Inflammatory Cytokine Release in a Mouse Model of Retinal Vein Occlusion

NLRP1 Acts as a Negative Regulator of Retinal Ganglion Cell Pyroptosis in a Mouse Model of Retinal Vein Occlusion

Loss of pleckstrin homology domain and leucine rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via Akt-GSK-3β-Nrf2 pathway

Live porcine eye model studies of subretinal injection using handheld endoscopy OCT integrated injector

Mesenchymal Stem Cell-Derived Exosomes as Drug Carriers for Delivering miRNA-29b to Ameliorate Inflammation in Corneal Injury Via Activating Autophagy

Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing

The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes

Optineurin dynamically regulates photoreceptor outer segment phagocytosis and lysosome biogenesis in the retinal pigment epithelium

Ceramide-mediated apical exosome release by the RPE triggers infiltration of microglia into the subretinal space in models of macular degeneration

The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability

Integrated Whole-Exome and Transcriptome Sequencing Indicated Dysregulation of Cholesterol Metabolism in Eyelid Sebaceous Gland Carcinoma

Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

Ubiquitination-Related miRNA–mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol

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