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Clinical and Epidemiologic Research January 2025

Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

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Yanping Chen; Ruilin Xiong; Jian Zhang; Shaopeng Yang; Huangdong Li; Ziyu Zhu; Peiyuan Wang; Mingguang He; Yingfeng Zheng; Wei Wang
TAGS: adult, child, eye, incidence, myopia, vision, visual impairment, blindness, world health organization
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):2. https://doi.org/10.1167/iovs.66.1.2

Includes: Supplemental Content

Glaucoma October 2024

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

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Jian Wu; Ruyue Li; Sirui Zhu; Kezhe Chen; Caixia Lin; Jiaxin Tian; Lijie Pan; Hongyi Liu; Xu Jia; Ziyu Yu; Zhidong Li; Yingting Zhu; Wei Liu; Chenlong Yang; Chiwai Wong; Ningli Wang; Yehong Zhuo; for the Non-Human Primate Eye Study Group
TAGS: glaucoma, macaca fascicularis, retinal nerve fiber layer, eye, cercopithecidae, intraocular pressure
Trans. Vis. Sci. Tech.. 2024; 13(10):6. https://doi.org/10.1167/tvst.13.10.6

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Exposure-based Learning Improved Orientation Discrimination Under Visual Crowding

Yanru Chen; Kunyun Wang; Cong Yu; Junyun Zhang

Journal of Vision. 2024; 24(10):1411. https://doi.org/10.1167/jov.24.10.1411

Clinical and Epidemiologic Research August 2024

Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia

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Cong Li; Yanping Chen; Shaopeng Yang; Ruilin Xiong; Riqian Liu; Ziyu Zhu; Shida Chen; Mingguang He; Wei Wang
TAGS: myopia, visual field defects, risk factors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):43. https://doi.org/10.1167/iovs.65.10.43

Includes: Supplemental Content

Glaucoma August 2024

Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

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Chia-Chen Hsu; Fang-Pai Lin; Hao-Chen Tseng; Pin Kuan Ho; Yi-Hsun Chen; Yann-Guang Chen; Da-Wen Lu; Yi-Hao Chen; Jian-Liang Chou; Hsin-Chih Chen; Yu Chuan Huang
TAGS: intraocular pressure, microspheres, myosin light chain kinase, ocular hypertension, open-angle glaucoma, oryctolagus cuniculus, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):17. https://doi.org/10.1167/iovs.65.10.17

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2024

Forecasting Myopic Maculopathy Risk Over a Decade: Development and Validation of an Interpretable Machine Learning Algorithm

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Yanping Chen; Shaopeng Yang; Riqian Liu; Ruilin Xiong; Yueye Wang; Cong Li; Yingfeng Zheng; Mingguang He; Wei Wang
TAGS: area under the roc curve, cohort studies, machine learning, macular disorders, myopia, myopic macular degeneration, follow-up, datasets, diagnostic imaging, calibration
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):40. https://doi.org/10.1167/iovs.65.6.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Activation of choroidal CD8+ T cells in response to injuries of the retinal pigment epithelium (RPE)

James Regun Karmoker; Sarah Bounds; Yan Chen; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):745.

ARVO Annual Meeting Abstract June 2024

ChatGPT and Ocular Ultrasound: Pioneering Enhanced Visual Question Answering in Medical Diagnostics

Fan Song; Weiyi Zhang; Yao Li; Yanxian Chen; Yingfeng Zheng; Wei Peng; Danli Shi; Mingguang He

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2364.

ARVO Annual Meeting Abstract June 2024

Physiological Growth of Axial Length in Myopic Eyes: A 6-Year Cohort Study on Children and Teenagers

Yanxian Chen; Yangfa Zeng; Mingguang He

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2709.

ARVO Annual Meeting Abstract June 2024

Lipid nanoparticle delivery of adenine base editors as a potential treatment for inherited retinal diseases

Victoria AC Palmgren; Miffy Hok Yan Cheng; Tiffany Carlaw; Tessa Morin; Colin JD Ross; Pieter R Cullis; Robert S Molday

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6056.

ARVO Annual Meeting Abstract June 2024

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

Linyu Shi; Weiwei Wu; Qi Yang; Sheng He; Mengke Zhu; Chenhua Yang; Shaoran Wang; Xing Wang; Xuan Yao; Alvin Luk; Hui Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6517.

ARVO Annual Meeting Abstract June 2024

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Weiwei Wu; Sheng He; Qi Yang; Chenhua Yang; Mengke Zhu; Shaoran Wang; Xuan Yao; Hui Yang; Alvin Luk; Linyu Shi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5091.

Vision Sciences Society Annual Meeting Abstract August 2023

Viewpoint adaptation reveals potential representational differences between 2D images and 3D objects

Zhiqing Deng; Jie Gao; Anthony Li; Yan Chen; Boyu Gao; Jody Culham; Juan Chen

Journal of Vision. 2023; 23(9):4783. https://doi.org/10.1167/jov.23.9.4783

Article August 2023

The impact of training on the inner–outer asymmetry in crowding

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Yan-Ru Chen; Yu-Wei Zhang; Jun-Yun Zhang
TAGS: crowding, training
Journal of Vision. 2023; 23(8):3. https://doi.org/10.1167/jov.23.8.3

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology June 2023

The Potential of Artemisinins as Novel Treatment for Thyroid Eye Disease by Inhibiting Adipogenesis in Orbital Fibroblasts

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Yan Guo; Yanglei Cheng; Hai Li; Hongyu Guan; Haipeng Xiao; Yanbing Li
TAGS: fibroblasts, graves' ophthalmopathy, western blotting, proto-oncogene proteins c-akt, flow cytometry, patient isolation, dimethyl sulfoxide, antimalarials
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):28. https://doi.org/10.1167/iovs.64.7.28

Includes: Supplemental Content

Genetics June 2023

Exploring the Effect of the Gut Microbiome on the Risk of Age-Related Macular Degeneration From the Perspective of Causality

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Kangcheng Liu; Jing Zou; Ruolan Yuan; Huimin Fan; Hanying Hu; Yanhua Cheng; Jingying Liu; Hua Zou; Zhipeng You
TAGS: age-related macular degeneration, genome-wide association study, intestinal bacteria, sensitivity analysis, datasets, rhodospirillales, genetics, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):22. https://doi.org/10.1167/iovs.64.7.22

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Characterization of the retinal phenotype in the offspring of maternal obesity

Anna Sergeyevna Usoltseva; Rui Cheng; Jiyang Cai; Jian-Xing Ma; Shaoning Jiang; Yan Chen

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):561.

ARVO Annual Meeting Abstract June 2023

Role of Lipin1 in lipid homeostasis in the retinal pigment epithelium

James Colton Hill; Anna Sergeyevna Usoltseva; Christopher Litwin; Yan Chen; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3771.

ARVO Annual Meeting Abstract June 2023

NFAT inhibition prevents retinal inflammation, leukostasis, and vascular leakage in diabetic retinopathy

Irina De la Huerta; Jorge Nunez; Jacob Poloway; Varun Reddy; Yanxin Chen; Gary McCollum; Taylor E Smith; John S. Penn

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2953.

ARVO Annual Meeting Abstract June 2023

Development of an RNA Targeting Based Gene Therapy Product for Neovascular Age-Related Macular Degeneration (nAMD)

Linyu Shi; Shaoran Wang; Weiwei Wu; Xing Wang; Qi Yang; Jingyu Zhang; Sheng He; Hongting Du; Jipeng Song; Chenhua Yang; Mengke Zhu; Xuan Yao; Hui Yang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):934.

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Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

Exposure-based Learning Improved Orientation Discrimination Under Visual Crowding

Long-Term Prediction and Risk Factors for Incident Visual Field Defect in Nonpathologic High Myopia

Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension

Forecasting Myopic Maculopathy Risk Over a Decade: Development and Validation of an Interpretable Machine Learning Algorithm

Activation of choroidal CD8+ T cells in response to injuries of the retinal pigment epithelium (RPE)

ChatGPT and Ocular Ultrasound: Pioneering Enhanced Visual Question Answering in Medical Diagnostics

Physiological Growth of Axial Length in Myopic Eyes: A 6-Year Cohort Study on Children and Teenagers

Lipid nanoparticle delivery of adenine base editors as a potential treatment for inherited retinal diseases

Efficient In-vitro and In-vivo CRISPR RNA Targeting Therapy of HG202 for Macular Degeneration

In-vivo Validation of HG004 Gene Replacement Therapy for Inherited Blindness

Viewpoint adaptation reveals potential representational differences between 2D images and 3D objects

The impact of training on the inner–outer asymmetry in crowding

The Potential of Artemisinins as Novel Treatment for Thyroid Eye Disease by Inhibiting Adipogenesis in Orbital Fibroblasts

Exploring the Effect of the Gut Microbiome on the Risk of Age-Related Macular Degeneration From the Perspective of Causality

Characterization of the retinal phenotype in the offspring of maternal obesity

Role of Lipin1 in lipid homeostasis in the retinal pigment epithelium

NFAT inhibition prevents retinal inflammation, leukostasis, and vascular leakage in diabetic retinopathy

Development of an RNA Targeting Based Gene Therapy Product for Neovascular Age-Related Macular Degeneration (nAMD)

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