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Multidisciplinary Ophthalmic Imaging April 2025

Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

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Yan-Jie Li; Zeng-Yu Zhang; Tian-Yue Liu; Hai-Yan Liu; Lu-Lu Shi; Rong-Xia Cao; Chao-Ran Lv; Zeng-Hui Zhang
TAGS: angiogram, fluid flow, microcirculation, optical coherence tomography, retina, thyroid carcinoma, papillary, carcinoma, perfusion, inflammation, inspection
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):73. https://doi.org/10.1167/iovs.66.4.73

Uveitis April 2025

Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population

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Hui Liu; Suo Guo; Yaning Liu; Guannan Su; Peizeng Yang
TAGS: chinese (other dialects), signs and symptoms, uveitis, anterior, chinese people, cytomegalovirus, intraocular pressure
Trans. Vis. Sci. Tech.. 2025; 14(4):2. https://doi.org/10.1167/tvst.14.4.2

Includes: Supplemental Content

Genetics March 2025

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

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Qiu-Yi Huo; Rui-Zheng Zhang; Wan-Nan Jia; Ya-Lei Wang; Xin Shen; Xin-Yao Chen; Tian-Hui Chen; Yan Liu; Ling-Hao Song; Xinyue Wang; Yong Lv; Ze-Xu Chen; Yong-Xiang Jiang
TAGS: biomechanics, cornea, ectopia lentis, fibrillin-1, marfan syndrome, mutation, genotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):23. https://doi.org/10.1167/iovs.66.3.23

Includes: Supplemental Content

Lens February 2025

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

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Yan Liu; Xinyue Wang; Linghao Song; Yang Sun; Zexu Chen; Wannan Jia; Xin Shen; Yalei Wang; Xinyao Chen; Qiuyi Huo; Pranav Prakash Edavi; Tianhui Chen; Yongxiang Jiang
TAGS: ectopia lentis, eye, intelligence, intraocular lens implant device, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(2):5. https://doi.org/10.1167/tvst.14.2.5

Includes: Supplemental Content

Retina January 2025

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

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Shizhen Lei; Yani Liu
TAGS: gastrointestinal microbiome, genetic correlation analysis, genetics, mendelian randomization analysis, retinal vein occlusion
Trans. Vis. Sci. Tech.. 2025; 14(1):5. https://doi.org/10.1167/tvst.14.1.5

Includes: Supplemental Content

Cornea December 2024

Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease

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Zhiwei Zha; Decheng Xiao; Zihao Liu; Fangli Peng; Xunjie Shang; Zhenzhen Sun; Yang Liu; Wei Chen
TAGS: cyclophosphamide, doxorubicin, prednisone, and vincristine, dry eye syndromes, nlr family, pyrin domain-containing 3 protein, signal pathway, signal transduction pathways, stress, mice, endoplasmic reticulum, inflammasomes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):34. https://doi.org/10.1167/iovs.65.14.34

Includes: Supplemental Content

Retina October 2024

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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Xiao Xie; Wenqi Wang; Hongyan Wang; Zhiping Zhang; Xiaomeng Yuan; Yanmei Shi; Yanfeng Liu; Qingjun Zhou; Tingting Liu
TAGS: artificial intelligence, biological markers, diabetes mellitus, type 2, diabetic nephropathy, perfusion, screening, random forest, complex
Trans. Vis. Sci. Tech.. 2024; 13(10):19. https://doi.org/10.1167/tvst.13.10.19

Multidisciplinary Ophthalmic Imaging September 2024

Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes

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Mary E. Marte; Kazuhiro Kurokawa; HaeWon Jung; Yan Liu; Marcel T. Bernucci; Brett J. King; Donald T. Miller
TAGS: diagnostic imaging, glaucoma, retina, eye, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):20. https://doi.org/10.1167/iovs.65.11.20

Includes: Multimedia, Supplemental Content

Retina August 2024

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

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Hong Zhou; Yan Liu; Tian Zhou; Ziqi Yang; Biyan Ni; Yang Zhou; Huiyi Xu; Xiaojing Lin; Shiya Lin; Chang He; Xialin Liu
TAGS: exosomes, interleukin-23, mesenchymal stem cells, micrornas, neuroprotective effect, retinal degeneration, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):8. https://doi.org/10.1167/iovs.65.10.8

Includes: Supplemental Content

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Glaucoma July 2024

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

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Nan Zhang; Pengyu Zhang; Xizhi Deng; Min Zhu; Yixin Hu; Dongxiao Ji; Lufan Li; Yang Liu; Wen Zeng; Min Ke
TAGS: extracellular matrix, glaucoma, glucocorticoids, mitochondria, mitochondrial toxicity, niacinamide, trabecular meshwork, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):1. https://doi.org/10.1167/iovs.65.8.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Imaging photoreceptor somas and other cellular structures in the outer nuclear layer of the living human eye

Yan Liu; Marcel Bernucci; Qiuzhi Ji; Kristen Bowles-Johnson; James Alan Crowell; Kazuhiro Kurokawa; Sela Damer-Daigle; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2176.

ARVO Annual Meeting Abstract June 2024

Cone photoreceptors with normal outer segment lengths may already be compromised in retinitis pigmentosa

Qiuzhi Ji; Yan Liu; Marcel Bernucci; James Alan Crowell; Kristen E Bowles Johnson; Matthew Keller; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3904.

ARVO Annual Meeting Abstract June 2024

Altered Cone Structure and Function in Subjects with Pentosan Polysulfate Sodium Toxicity

Kristen E Bowles Johnson; Qiuzhi Ji; Yan Liu; Marcel Bernucci; Tomas S Aleman; James Alan Crowell; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3903.

ARVO Annual Meeting Abstract June 2024

Human cone spectral sensitivity measured with optoretinography is consistent with Baylor’s electrophysiology cone data

Marcel Bernucci; Yan Liu; Qiuzhi Ji; James Alan Crowell; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3364.

ARVO Annual Meeting Abstract June 2024

Sub-clinical ganglion cell loss in glaucoma patients is 1-2 orders of magnitude higher than expected due to aging

Matthew Keller; Yan Liu; Kazuhiro Kurokawa; Brett King; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4947.

ARVO Annual Meeting Abstract June 2024

The Effect of Brimonidine 0.025% Ophthalmic Solution on Contrast Sensitivity, Pupil Size, and Intraocular Pressure: A Pilot Study

Yan-Ting Liu; Lorne Yudcovitch; John R Hayes

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3155.

ARVO Annual Meeting Abstract June 2024

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

Yang LIU; Megumi HONJO; Reiko YAMAGISHI; Makoto AIHARA

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):847.

ARVO Annual Meeting Abstract June 2024

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

Yen-Chiao Wang; Yuan Yong; Olivia Zolnik; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):520.

ARVO Annual Meeting Abstract June 2024

The role of Smad4 in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil Ghag; Winston Kao; Shizuya Saika; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):502.

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Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

Identification of Subtypes of Herpetic Anterior Uveitis and Characterization of Their Clinical Features and Visual Outcome in a Chinese Population

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

Imaging photoreceptor somas and other cellular structures in the outer nuclear layer of the living human eye

Cone photoreceptors with normal outer segment lengths may already be compromised in retinitis pigmentosa

Altered Cone Structure and Function in Subjects with Pentosan Polysulfate Sodium Toxicity

Human cone spectral sensitivity measured with optoretinography is consistent with Baylor’s electrophysiology cone data

Sub-clinical ganglion cell loss in glaucoma patients is 1-2 orders of magnitude higher than expected due to aging

The Effect of Brimonidine 0.025% Ophthalmic Solution on Contrast Sensitivity, Pupil Size, and Intraocular Pressure: A Pilot Study

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

The role of Smad4 in corneal development and homeostasis

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