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Retina October 2024

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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Xiao Xie; Wenqi Wang; Hongyan Wang; Zhiping Zhang; Xiaomeng Yuan; Yanmei Shi; Yanfeng Liu; Qingjun Zhou; Tingting Liu
TAGS: artificial intelligence, biological markers, diabetes mellitus, type 2, diabetic nephropathy, perfusion, screening, random forest, complex
Trans. Vis. Sci. Tech.. 2024; 13(10):19. https://doi.org/10.1167/tvst.13.10.19

Multidisciplinary Ophthalmic Imaging September 2024

Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes

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Mary E. Marte; Kazuhiro Kurokawa; HaeWon Jung; Yan Liu; Marcel T. Bernucci; Brett J. King; Donald T. Miller
TAGS: diagnostic imaging, glaucoma, retina, eye, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):20. https://doi.org/10.1167/iovs.65.11.20

Includes: Multimedia, Supplemental Content

Retina August 2024

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

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Hong Zhou; Yan Liu; Tian Zhou; Ziqi Yang; Biyan Ni; Yang Zhou; Huiyi Xu; Xiaojing Lin; Shiya Lin; Chang He; Xialin Liu
TAGS: exosomes, interleukin-23, mesenchymal stem cells, micrornas, neuroprotective effect, retinal degeneration, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):8. https://doi.org/10.1167/iovs.65.10.8

Includes: Supplemental Content

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Glaucoma July 2024

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

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Nan Zhang; Pengyu Zhang; Xizhi Deng; Min Zhu; Yixin Hu; Dongxiao Ji; Lufan Li; Yang Liu; Wen Zeng; Min Ke
TAGS: extracellular matrix, glaucoma, glucocorticoids, mitochondria, mitochondrial toxicity, niacinamide, trabecular meshwork, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):1. https://doi.org/10.1167/iovs.65.8.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Imaging photoreceptor somas and other cellular structures in the outer nuclear layer of the living human eye

Yan Liu; Marcel Bernucci; Qiuzhi Ji; Kristen Bowles-Johnson; James Alan Crowell; Kazuhiro Kurokawa; Sela Damer-Daigle; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2176.

ARVO Annual Meeting Abstract June 2024

Cone photoreceptors with normal outer segment lengths may already be compromised in retinitis pigmentosa

Qiuzhi Ji; Yan Liu; Marcel Bernucci; James Alan Crowell; Kristen E Bowles Johnson; Matthew Keller; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3904.

ARVO Annual Meeting Abstract June 2024

Altered Cone Structure and Function in Subjects with Pentosan Polysulfate Sodium Toxicity

Kristen E Bowles Johnson; Qiuzhi Ji; Yan Liu; Marcel Bernucci; Tomas S Aleman; James Alan Crowell; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3903.

ARVO Annual Meeting Abstract June 2024

Human cone spectral sensitivity measured with optoretinography is consistent with Baylor’s electrophysiology cone data

Marcel Bernucci; Yan Liu; Qiuzhi Ji; James Alan Crowell; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3364.

ARVO Annual Meeting Abstract June 2024

Sub-clinical ganglion cell loss in glaucoma patients is 1-2 orders of magnitude higher than expected due to aging

Matthew Keller; Yan Liu; Kazuhiro Kurokawa; Brett King; Donald Thomas Miller

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4947.

ARVO Annual Meeting Abstract June 2024

The Effect of Brimonidine 0.025% Ophthalmic Solution on Contrast Sensitivity, Pupil Size, and Intraocular Pressure: A Pilot Study

Yan-Ting Liu; Lorne Yudcovitch; John R Hayes

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3155.

ARVO Annual Meeting Abstract June 2024

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

Yang LIU; Megumi HONJO; Reiko YAMAGISHI; Makoto AIHARA

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):847.

ARVO Annual Meeting Abstract June 2024

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

Yen-Chiao Wang; Yuan Yong; Olivia Zolnik; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):520.

ARVO Annual Meeting Abstract June 2024

The role of Smad4 in corneal development and homeostasis

Shingo Yasuda; Yong Yuan; Jianhua Zhang; Yen-Chiao Wang; Sachin Anil Ghag; Winston Kao; Shizuya Saika; Chia-Yang Liu

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):502.

ARVO Annual Meeting Abstract June 2024

Ultrastructure and morphology of healing corneal stroma in a keratocyte-specific hyaluronan synthases 2-deficient mouse

Ai Matsushita; Takayoshi Sumioka; Yuka Okada; Hiroki Iwanishi; Masayasu Miyajima; Chia-Yang Liu; Winston Kao; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):485.

ARVO Annual Meeting Abstract June 2024

Bioanalytical solutions and immunogenicity challenges of species-matched antibodies in preclinical studies while investigating protein-loaded long-acting intravitreal delivery technologies

Kelly Loyet; Hilda Hernandez-Barry; Kathy Barrett; Mauricio Maia; Yanqiu Liu; Hanine Rafidi; Danielle Mandikian; Andy Boswell; Joyce Chan; Laetitia Comps-Agrar; Susan Ritger Crowell; Steven Laing; Amin Famili; Whitney Shatz-Binder; Devin Tesar; Robert Kelley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3785.

ARVO Annual Meeting Abstract June 2024

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

chia-yang liu; Yong Yuan; Yen-Chiao Wang; Winston Kao

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3647.

ARVO Annual Meeting Abstract June 2024

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 1 year follow-up of an investigator initiated trial

Yang Liu; Minlu Song; Jingyang Feng; Lihong Li; Fenghua Wang; Yuanyuan Gong; Hong Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4378.

ARVO Annual Meeting Abstract June 2024

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Junran Sun; Yang Liu; Yidong Wu; Tong Li; Fenghua Wang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5332.

ARVO Annual Meeting Abstract June 2024

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 9-month follow-up of a phase 1 clinical trial

Minlu Song; Yang Liu; Jingyang Feng; Yuanyuan Gong; Hong Wang; Lihong Li; Fenghua Wang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6107.

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Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

Characterizing Presumed Displaced Retinal Ganglion Cells in the Living Human Retina of Healthy and Glaucomatous Eyes

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Protective Effect of Nicotinamide Riboside on Glucocorticoid-Induced Glaucoma: Mitigating Mitochondrial Damage and Extracellular Matrix Deposition

Imaging photoreceptor somas and other cellular structures in the outer nuclear layer of the living human eye

Cone photoreceptors with normal outer segment lengths may already be compromised in retinitis pigmentosa

Altered Cone Structure and Function in Subjects with Pentosan Polysulfate Sodium Toxicity

Human cone spectral sensitivity measured with optoretinography is consistent with Baylor’s electrophysiology cone data

Sub-clinical ganglion cell loss in glaucoma patients is 1-2 orders of magnitude higher than expected due to aging

The Effect of Brimonidine 0.025% Ophthalmic Solution on Contrast Sensitivity, Pupil Size, and Intraocular Pressure: A Pilot Study

Autotaxin level is related with retinal pigment epithelial barrier function in mouse eyes with diabetic retinopathy

SMAD4 together with YAP and TAZ can serve as novel targets to intervene CE-like pathological corneal stroma thinning found in TGFb signaling deficiency mouse lines Tgfbr1 kera-cko and Tgfbr2 kera-cko .

The role of Smad4 in corneal development and homeostasis

Ultrastructure and morphology of healing corneal stroma in a keratocyte-specific hyaluronan synthases 2-deficient mouse

Bioanalytical solutions and immunogenicity challenges of species-matched antibodies in preclinical studies while investigating protein-loaded long-acting intravitreal delivery technologies

Tbr1/Smad4 double knockout demonstrated that Smad4 played a pivotal role in Tbr1-dependent ECM synthesis and Tbr1-independent ECM degradation for maintaining corneal homeostasis

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 1 year follow-up of an investigator initiated trial

Investigator-initiated study of intravitreal gene therapy with AAV-RC-C08 expressing RS1 for X-linked juvenile retinoschisis patients

Subretinal LX102 gene therapy for neovascular age-related macular degeneration (nAMD): 9-month follow-up of a phase 1 clinical trial

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