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Retina January 2025

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

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Federico Corti; Filippo Locri; Flavia Plastino; Paola Perrotta; Krisztina Zsebo; Emma Ristori; Xiangyun Yin; Eric Song; Helder André; Michael Simons
TAGS: antibodies, choroidal neovascularization, edema, inflammation, lasers, mice, syndecan, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, intravitreal injections
Trans. Vis. Sci. Tech.. 2025; 14(1):10. https://doi.org/10.1167/tvst.14.1.10

Includes: Supplemental Content

Retina October 2024

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

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Ying Xiang Han; Xiao Xiao Guo; Ya Xing Wang; Jost B. Jonas; Xi Chen; Xiao Fei Wang
TAGS: sclera, staphyloma, macular disorders, eye, magnetic resonance imaging
Trans. Vis. Sci. Tech.. 2024; 13(10):41. https://doi.org/10.1167/tvst.13.10.41

Includes: Supplemental Content

Biochemistry and Molecular Biology September 2024

Metabolic Phenotyping of Healthy and Diseased Human RPE Cells

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Saira Rizwan; Beverly Toothman; Bo Li; Abbi L. Engel; Rayne R. Lim; Sheldon Niernberger; Jinyu Lu; Cloe Ratliff; Yinxiao Xiang; Mark Eminhizer; Jennifer R. Chao; Jianhai Du
TAGS: glutamine, nutrients, phenotype determination, retinal pigment cell, sugars, induced pluripotent stem cells, amino acids
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):5. https://doi.org/10.1167/iovs.65.11.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Early metabolic signature of the eye and brain in Alzheimer’s disease

Yinxiao Xiang; Rachel McNeel; Tuan Ngo; Meghashri Saravanan; Yekai Wang; Mark Eminhizer; Saira Rizwan; Audrey Anderson; Jianhai Du

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):190.

ARVO Annual Meeting Abstract June 2024

Assessment of artificial intelligence to determine referral pathways in a real-world population of the English Diabetic Eye Screening Programme (DESP)

Tunde Peto; Giulia Bignami; Anne-Marie Cairns; Ashleigh Kernohan; Philip Kirby; Sobha Sivaprasad; Dominik Temmesfeld; Luke Vale; Sunny Virmani; Lin Yang; Xiang Yin; Xiang Ji; Luke Nicholson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4921.

Anatomy and Pathology/Oncology March 2024

scRNA-Seq: First Atlas and Cellular Landscape of Lacrimal Sac: Implications in Primary Acquired Nasolacrimal Duct Obstruction Pathogenesis

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Wenyue Zhang; Huan Huang; Xueru Liu; Leilei Zhang; Lunhao Li; Yi Ding; Yichuan Xiao; Mohammad Javed Ali; Hao Sun; Caiwen Xiao
TAGS: epithelial cells, genes, lacrimal sac, nasolacrimal duct obstruction, pathogenesis, rna, small cytoplasmic, neutrophils, b-lymphocytes, inflammation, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):38. https://doi.org/10.1167/iovs.65.3.38

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2023

Comparison of Ophthalmic Artery Morphological Characteristics and Retinal Vessel Diameter for Identifying Ocular Ischemic Syndrome

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Xue-ru Cheng; Lu Zhao; Ying-xiang Huang; Yan-ling Wang; Jia-lin Wang
TAGS: language morphology, morphology, ophthalmic artery, retinal ischemia, retinal vessels, eye, computed tomographic angiography, roc curve
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):20. https://doi.org/10.1167/iovs.64.12.20

Cornea & External Disease August 2023

0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response

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Kai Zhao; Fen Hu; Zhaowei Zhang; Xiaoyue Yin; He Wang; Mingxin Li
TAGS: aspergillus fumigatus, hypochlorous acid, inflammatory response, keratitis, rats, cornea
Trans. Vis. Sci. Tech.. 2023; 12(8):3. https://doi.org/10.1167/tvst.12.8.3

Visual Neuroscience August 2023

Early Visual Deprivation Impairs Functional Development of the Visual Ventral Stream

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Yifan Xiang; Jingwen Yang; Leyan Gao; Zelin Chen; Jingjing Chen; Zhirui Yang; Xiaoqing Gao; Zhuoling Lin; Xiaohang Wu; Shuo Lu; Haotian Lin
TAGS: child, depression, post-stroke, persistent speech disorders, vision, visual processing, attention, adult, visual cortex, face, electroencephalography
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):1. https://doi.org/10.1167/iovs.64.11.1

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics June 2023

Decomposing the Response Time in Amblyopia: A Drift Diffusion Model Analysis

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Xiaowei Ruan; Liang Lin; Xiaoxiao Ying; Hanyi Zhang; Junli Yuan; Cheng Li; Yan Yang; Jinli Zhu; Ruyin Chen; Fang Hou
TAGS: amblyopia, reaction time, diffusion, eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):25. https://doi.org/10.1167/iovs.64.7.25

ARVO Annual Meeting Abstract June 2023

Effect of prematurity on foveal development persists through infancy

Xiao Yi Zhou; Gui-Shuang Ying; Vincent Tai; Shwetha Mangalesh; Cynthia A Toth; Xi Chen

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5428.

Immunology and Microbiology December 2022

Microbiological Characteristics of Ocular Surface Associated With Dry Eye in Children and Adolescents With Diabetes Mellitus

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Zhangling Chen; Yan Jia; Ying Xiao; Qiurong Lin; Yu Qian; Zhaoyu Xiang; Lipu Cui; Xinran Qin; Shuli Chen; Chenhao Yang; Haidong Zou
TAGS: adolescent, child, diabetes mellitus, dry eye syndromes, ocular surfaces, rna, ribosomal, 16s, microorganisms
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):20. https://doi.org/10.1167/iovs.63.13.20

Immunology and Microbiology February 2022

Sensory Nerve Retraction and Sympathetic Nerve Innervation Contribute to Immunopathology of Murine Recurrent Herpes Stromal Keratitis

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Hongmin Yun; Xiao-Tang Yin; Patrick M. Stuart; Anthony J. St. Leger
TAGS: cornea, human herpesvirus 1, mice, neurons, recurrence, sensory nerves, stromal keratitis, sympathetic nerve, virus reactivation, ultraviolet b radiation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):4. https://doi.org/10.1167/iovs.63.2.4

Includes: Supplemental Content

Cornea August 2021

Exploring the Mechanism of the miRNA-145/Paxillin Axis in Cell Metabolism During VEGF-A–Induced Corneal Angiogenesis

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Wanju Yang; Yanning Yang; Shanshan Wan; Ya Xu; Jing Li; Lu Zhang; Wanruo Guo; Yijun Zheng; Yi Xiang; Yiqiao Xing
TAGS: corneal neovascularization, metabolism, vascular endothelial growth factor a, micrornas, angiogenesis, lactic acid, 1-phosphatidylinositol 3-kinase, proto-oncogene proteins c-akt
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):25. https://doi.org/10.1167/iovs.62.10.25

Visual Psychophysics and Physiological Optics July 2021

Defective Temporal Window of the Foveal Visual Processing in High Myopia

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Haiyan Zheng; Xiaoxiao Ying; Xianghang He; Jia Qu; Fang Hou
TAGS: fovea centralis, myopia, visual processing, perceptual masking, noise
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):11. https://doi.org/10.1167/iovs.62.9.11

ARVO Annual Meeting Abstract June 2021

Sensory nerve retraction and sympathetic nerve innervation are involved in the immunopathology of murine recurrent Herpes Stromal Keratitis (HSK)

Hongmin Yun; Xiao-Tang Yin; Patrick Stuart; Anthony St. Leger

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):922.

Cornea February 2021

Associations Between Regional Environment and Cornea-Related Morphology of the Eye in Young Adults: A Large-Scale Multicenter Cross-Sectional Study

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Jiaonan Ma; Lanqin Zhao; Yahan Yang; Dongyuan Yun; Patrick Yu-Wai-Man; Yi Zhu; Chuan Chen; Ji-Peng Olivia Li; Mengdi Li; Yan Zhang; Tingxin Cui; Xiangbing Meng; Lin Zhang; Jiamei Zhang; Yi Song; Yulin Lei; Jianguo Liu; Xiaojin Huangfu; Li Jiang; Jinfeng Cai; Huiying Wu; Liqiang Shang; Dan Wen; Xianglong Yi; Yan Zhang; Xin Li; Jing Xiao; Rui He; Yang Yang; Jun Yang; George P. M. Cheng; Ji Bai; Xingwu Zhong; Hua Guo; Pisong Yan; Yan Wang; Haotian Lin
TAGS: cornea, eye, language morphology, morphology, young adult
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):35. https://doi.org/10.1167/iovs.62.2.35

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Longitudinal Sub-Retinal Pigment Epithelium Disease Burden Assessment in Neovascular Age-Related Macular Degeneration: Results from the OSPREY Study

Atsuro Uchida; Julie Clark; Robert Zahid; Natalia Albuquerque Lucena Figueiredo; Leina Lunasco; Thuy Le; Jamie Reese; Xiang Yi Meng; Sunil K Srivastava; Justis Ehlers

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2546.

ARVO Annual Meeting Abstract June 2020

Dimethyl Malonate disrupts the development of recurrent herpetic stromal keratitis, but not primary herpes simplex keratitis

Nicholas Koh Baugnon; Xiao-Tang Yin; Patrick Stuart

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):438.

Special Issue January 2020

Development and Evaluation of a Deep Learning System for Screening Retinal Hemorrhage Based on Ultra-Widefield Fundus Images

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Zhongwen Li; Chong Guo; Danyao Nie; Duoru Lin; Yi Zhu; Chuan Chen; Yifan Xiang; Fabao Xu; Chenjin Jin; Xiayin Zhang; Yahan Yang; Kai Zhang; Lanqin Zhao; Ping Zhang; Yu Han; Dongyuan Yun; Xiaohang Wu; Pisong Yan; Haotian Lin
TAGS: datasets, deep learning, retinal hemorrhage, screening, ophthalmologists, reference standards, macula densa, macula lutea
Trans. Vis. Sci. Tech.. 2020; 9(2):3. https://doi.org/10.1167/tvst.9.2.3

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Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

Metabolic Phenotyping of Healthy and Diseased Human RPE Cells

Early metabolic signature of the eye and brain in Alzheimer’s disease

Assessment of artificial intelligence to determine referral pathways in a real-world population of the English Diabetic Eye Screening Programme (DESP)

scRNA-Seq: First Atlas and Cellular Landscape of Lacrimal Sac: Implications in Primary Acquired Nasolacrimal Duct Obstruction Pathogenesis

Comparison of Ophthalmic Artery Morphological Characteristics and Retinal Vessel Diameter for Identifying Ocular Ischemic Syndrome

0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response

Early Visual Deprivation Impairs Functional Development of the Visual Ventral Stream

Decomposing the Response Time in Amblyopia: A Drift Diffusion Model Analysis

Effect of prematurity on foveal development persists through infancy

Microbiological Characteristics of Ocular Surface Associated With Dry Eye in Children and Adolescents With Diabetes Mellitus

Sensory Nerve Retraction and Sympathetic Nerve Innervation Contribute to Immunopathology of Murine Recurrent Herpes Stromal Keratitis

Exploring the Mechanism of the miRNA-145/Paxillin Axis in Cell Metabolism During VEGF-A–Induced Corneal Angiogenesis

Defective Temporal Window of the Foveal Visual Processing in High Myopia

Sensory nerve retraction and sympathetic nerve innervation are involved in the immunopathology of murine recurrent Herpes Stromal Keratitis (HSK)

Associations Between Regional Environment and Cornea-Related Morphology of the Eye in Young Adults: A Large-Scale Multicenter Cross-Sectional Study

Longitudinal Sub-Retinal Pigment Epithelium Disease Burden Assessment in Neovascular Age-Related Macular Degeneration: Results from the OSPREY Study

Dimethyl Malonate disrupts the development of recurrent herpetic stromal keratitis, but not primary herpes simplex keratitis

Development and Evaluation of a Deep Learning System for Screening Retinal Hemorrhage Based on Ultra-Widefield Fundus Images

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