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ARVO Annual Meeting Abstract June 2025

Leveraging Structure-Based Network Analysis to Identify Putative Causative Variants of Inherited Retinal Disease

Blake M. Hauser; Yuyang Luo; Aamilah Chowdhury; Anusha Nathan; Ahmad al-Moujahed; Demetrios Vavvas; Jason Comander; Eric A Pierce; Emily Place; Kinga Maria Bujakowska; Gaurav D. Gaiha; Elizabeth J Rossin

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1344.

ARVO Annual Meeting Abstract June 2025

Hexokinase-2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis through Metabolic Reprogramming

wei chen; Dan Jiang; Yining Sun; Yuhong Luo

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5911.

ARVO Annual Meeting Abstract June 2025

Integrative ‘omic analysis of clinical traits and genes contributing towards epiretinal membranes: Phenome- and genome- wide association analysis across >1 million individuals

Seyedeh Maryam Zekavat; William Phillip Miller; Bryan Gorman; Joel Rämö; Bryan Kaplan; Yuyang Luo; Satoshi Koyama; Anna M Stagner; Neal S Peachey; Leo A Kim; Pradeep Natarajan; Sudha K Iyengar; Elizabeth J Rossin; Yoon Kim

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):451.

ARVO Annual Meeting Abstract June 2025

Short-read whole genome sequencing comprehensively identifies causal mutations in a Filipino cohort with Aniridia

Michael Carreon Sibulo; Ma. Carmela Botor Guevarra; Divine Joe Grace Marcelino; Clayvon J. Pascua; Yuyang Luo; Juerg Straubhaar; Jason Turner-Maier; Jessica Marie R. Abaño; Kathleen M. Castro; Ronel Vincent L. Guerzon; Jose Maria D. Martinez; Ma. Catherina C. Nasol; Ma. Dominga B. Padilla; Ronald Antonio N. Reyna; Joceyln L. Sy; Patricia Yukiji J. Villa; Denise Polly G. Chao-Po; Edward Ryan A. Collantes; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1341.

ARVO Annual Meeting Abstract June 2025

Whole Genome Sequencing of two Filipino families identifies Phosphoinositide 5-phosphatase, FIG4, as a novel candidate gene for Early-onset Glaucoma

Divine Marcelino; Ma. Carmela Botor Guevarra; Yuyang Luo; Patricia Tacata; Elizabeth Aileen Giller; Earl Edward Cruz; Renato Rayel; Nilo Vincent Florcruz; Norman Aquino; Manuel Delfin; Edward Ryan A. Collantes; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1315.

ARVO Annual Meeting Abstract June 2025

Pharmacogenetic Study of Response to Intravitreal Anti-VEGF Therapy for Macular Edema Associated with Retinal Vein Occlusion

Jyoti Lama; Yuyang Luo; Ingrid U Scott; Neal Oden; Paul VanVeldhuisen; Katie Huynh; Michael S Ip; Barbara A Blodi; Lucia Sobrin; Ayellet Segré

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2603.

ARVO Annual Meeting Abstract June 2025

Sex bias in retinal gene expression, regulation and disease

Ting-Yi Lin; Jayshree Advani; Milton English; Sudeep Mehrotra; Puja Mehta; Yuyang Luo; Deborah A Ferrington; Ayellet Vered Segre; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3997.

ARVO Annual Meeting Abstract June 2025

Activation or overexpression of TASK-3 protects retinal ganglion cells and visual function after injury

Jiali Zhang; Yuncheng Luo; Ruotian Jiang; Xiangyi Wen; Longqian Liu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3592.

Refractive Intervention May 2025

Distance of Corneal Vertex and Effective Optical Zone Margin Following Keratorefractive Lenticule Extraction in Myopic Astigmatism

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Xuyun Meng; Hui Ding; Hong He; Zhenduo Yang; Xiaodan Chen; Shisi Hu; Anzhen Li; Xingxing Wang; Yuhan Luo; Xingwu Zhong
TAGS: astigmatism, cornea, crown of head, optics, postoperative care, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(5):21. https://doi.org/10.1167/tvst.14.5.21

Visual Neuroscience November 2024

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

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Zhonghao Yu; Yue Guan; Tian Xia; Xuanwen Li; Mingyue Liu; Yujia Huo; Zhuowei Wang; Zhirong Liu; Yuting Luo; Wentao Yan; Lanfang Sun; Wencan Wu; Baoguo Shen; Yikui Zhang
TAGS: optic nerve, rna, rna, messenger, white matter
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):25. https://doi.org/10.1167/iovs.65.13.25

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2024

Structure-based network analysis identifies pathogenic variants in patients with inherited retinal disease

Blake M. Hauser; Yuyang Luo; Anusha Nathan; Demetrios Vavvas; Jason Comander; Eric A Pierce; Emily Place; Kinga Maria Bujakowska; Gaurav D Gaiha; Elizabeth J Rossin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6029.

ARVO Annual Meeting Abstract June 2024

Genome-wide association study (GWAS) of anti-VEGF treatment response in diabetic macular edema identifies genetic associations with retina central subfield thickness and visual acuity improvement

Yuyang Luo; Jiali Wang; Danni Liu; Sandra Galusic; Jacqueline Otto; Eli Stahl; Amelia J. Averitt; Giovanni Coppola; Jennifer K Sun; Adam Glassman; Lucia Sobrin; Ayellet Segre

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4881.

Artificial Intelligence April 2024

Trends in the Prevalence of Common Retinal and Optic Nerve Diseases in China: An Artificial Intelligence Based National Screening

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Ruiheng Zhang; Li Dong; Xuefei Fu; Lin Hua; Wenda Zhou; Heyan Li; Haotian Wu; Chuyao Yu; Yitong Li; Xuhan Shi; Yangjie Ou; Bing Zhang; Bin Wang; Zhiqiang Ma; Yuan Luo; Meng Yang; Xiangang Chang; Zhaohui Wang; Wenbin Wei
TAGS: artificial intelligence, china, optic nerve disorders, prevalence, screening, trend
Trans. Vis. Sci. Tech.. 2024; 13(4):28. https://doi.org/10.1167/tvst.13.4.28

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

The clinical utility of a glaucoma polygenic risk score in four European-ancestry cohorts

Victor Anthony de Vries; Akiko Hanyuda; Joëlle Vergroesen; Ron Do; David S Friedman; Peter Kraft; Yuyang Luo; Jessica Tran; Sze H Wong; Nazlee Zebardast; Caroline C W Klaver; Janey L Wiggs; Ayellet V. Segre; Jae H Kang; Wishal Ramdas; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):99.

ARVO Annual Meeting Abstract June 2023

Systematic approach to analyzing protein structure predicts mutations associated with inherited retinal disease

Blake M. Hauser; Yuyang Luo; Anusha Nathan; James Chodosh; Lucia Sobrin; Eric A Pierce; Bruce Walker; Gaurav Gaiha; Elizabeth Rossin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3267.

ARVO Annual Meeting Abstract June 2023

Baseline visual field patterns identified by archetypal analysis are associated with glaucoma onset and progression in the Ocular Hypertension Treatment Study

Rishabh Singh; Yan Zhao; John H Fingert; Mae O Gordon; Michael A Kass; Yuyang Luo; Ayellet V. Segre; Janey L Wiggs; Tobias Elze; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):349.

ARVO Annual Meeting Abstract June 2023

Evaluation of Polygenic Risk Score Prediction and Validation of Diagnostic Codes of Primary Open-Angle Glaucoma in Electronic Health Record (EHR)-linked Biobanks

Joyce Kang; Jessica Tran; Kasem Seresirikachorn; Urvi Gupta; Elaine Han; Thi Ha Vy; Ghislain Rocheleau; Ron Do; Yan Zhao; Yuyang Luo; Ayellet V. Segre; Janey L Wiggs; Louis R Pasquale; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2788.

ARVO Annual Meeting Abstract June 2023

The role of homology modeling on improving associations between functional and structural mutation using structural based network analysis

Yuyang Luo; Blake M. Hauser; Elizabeth Rossin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1870.

ARVO Annual Meeting Abstract June 2022

Flt-1 and KDR knockdown affects receptor tyrosine phosphorylation and VEGF-mediated neurite growth in PC12 neuronal cells

Joy Sarkar; Daniel Lara; Eitan Katz; Qiang Zhou; Yuncin Luo; Evguenia Ivakhnitskaia; Michael Sun; Victor H Guaiquil; Mark Rosenblatt

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3655 – A0220.

Vision Sciences Society Annual Meeting Abstract September 2021

Decreases loom larger than increases: A perceptual account for loss aversion

Yu Luo; Darko Odic; Jiaying Zhao

Journal of Vision. 2021; 21(9):2920. https://doi.org/10.1167/jov.21.9.2920

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Leveraging Structure-Based Network Analysis to Identify Putative Causative Variants of Inherited Retinal Disease

Hexokinase-2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis through Metabolic Reprogramming

Integrative ‘omic analysis of clinical traits and genes contributing towards epiretinal membranes: Phenome- and genome- wide association analysis across >1 million individuals

Short-read whole genome sequencing comprehensively identifies causal mutations in a Filipino cohort with Aniridia

Whole Genome Sequencing of two Filipino families identifies Phosphoinositide 5-phosphatase, FIG4, as a novel candidate gene for Early-onset Glaucoma

Pharmacogenetic Study of Response to Intravitreal Anti-VEGF Therapy for Macular Edema Associated with Retinal Vein Occlusion

Sex bias in retinal gene expression, regulation and disease

Activation or overexpression of TASK-3 protects retinal ganglion cells and visual function after injury

Distance of Corneal Vertex and Effective Optical Zone Margin Following Keratorefractive Lenticule Extraction in Myopic Astigmatism

Overcoming Low mRNA Expression in White Matter: A Protocol for RNA Extraction From the Optic Nerve in Large Animals for Transcriptomic Analysis

Structure-based network analysis identifies pathogenic variants in patients with inherited retinal disease

Genome-wide association study (GWAS) of anti-VEGF treatment response in diabetic macular edema identifies genetic associations with retina central subfield thickness and visual acuity improvement

Trends in the Prevalence of Common Retinal and Optic Nerve Diseases in China: An Artificial Intelligence Based National Screening

The clinical utility of a glaucoma polygenic risk score in four European-ancestry cohorts

Systematic approach to analyzing protein structure predicts mutations associated with inherited retinal disease

Baseline visual field patterns identified by archetypal analysis are associated with glaucoma onset and progression in the Ocular Hypertension Treatment Study

Evaluation of Polygenic Risk Score Prediction and Validation of Diagnostic Codes of Primary Open-Angle Glaucoma in Electronic Health Record (EHR)-linked Biobanks

The role of homology modeling on improving associations between functional and structural mutation using structural based network analysis

Flt-1 and KDR knockdown affects receptor tyrosine phosphorylation and VEGF-mediated neurite growth in PC12 neuronal cells

Decreases loom larger than increases: A perceptual account for loss aversion

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