Biochemistry and Molecular Biology

Showing 1 – 20 of 3155

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Retinal Cell Biology March 2019

Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

PDF

Rupali Vohra; Blanca I. Aldana; Helle Waagepetersen; Linda H. Bergersen; Miriam Kolko
TAGS: lactates, glutamate, glucose
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):999-1008. doi: 10.1167/iovs.18-25458

Retinal Cell Biology March 2019

Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury

PDF

Wei Liu; Fan Xia; Yonju Ha; Shuang Zhu; Yi Li; Oluwarotimi Folorunso; Aryan Pashaei-Marandi; Pei-Yi Lin; Ronald G. Tilton; Anson P. Pierce; Hua Liu; Wenbo Zhang
TAGS: ischemia, wounds and injuries, eye, mice, proteins, stress, neuroprotective effect, protein overexpression, retina, reperfusion injury, heat-shock proteins 70, reperfusion therapy, retinal ischemia, immunohistochemistry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):965-977. doi: 10.1167/iovs.18-26216

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2019

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa

PDF

Ulisse Bocchero; Beatrice M. Tam; Colette N. Chiu; Vincent Torre; Orson L. Moritz
TAGS: animals, transgenic, darkness, electroretinography, photons, phototransduction, retinitis pigmentosa, rhodopsin, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):933-943. doi: 10.1167/iovs.18-25347

Includes: Supplemental Content

Cornea March 2019

Mediators of Corneal Haze Following Implantation of Presbyopic Corneal Inlays

PDF

Beau J. Fenner; Yu-Chi Liu; Siew Kwan Koh; Yan Gao; Lu Deng; Roger W. Beuerman; Lei Zhou; Julian T. S. Theng; Jodhbir S. Mehta
TAGS: corneal opacity, cornea, eye, proteins, proteomics, implantation procedure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):868-876. doi: 10.1167/iovs.18-25761

Includes: Supplemental Content

Special Issue February 2019

IMI – Myopia Genetics Report

PDF

Milly S. Tedja; Annechien E. G. Haarman; Magda A. Meester-Smoor; Jaakko Kaprio; David A. Mackey; Jeremy A. Guggenheim; Christopher J. Hammond; Virginie J. M. Verhoeven; Caroline C. W. Klaver; for the CREAM Consortium
TAGS: genes, myopia, refractive errors, genetics, genome-wide association study, universities
Invest. Ophthalmol. Vis. Sci.. 2019; 60(3):M89-M105. doi: 10.1167/iovs.18-25965

Glaucoma February 2019

Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation

PDF

Ying Ying Sun; Yong-Feng Yang; Kate E. Keller
TAGS: actins, western blotting, myosin, dimethyl sulfoxide, lentivirus, matrix metalloproteinases, microscopy, confocal, perfusion, phagocytosis, trabecular meshwork, proteins, regulation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):843-851. doi: 10.1167/iovs.18-26055

Includes: Supplemental Content

Retina February 2019

The Neuroprotective Peptide PACAP1-38 Contributes to Horizontal Cell Development in Postnatal Rat Retina

PDF

Viktoria Denes; Orsolya Hideg; Zsolt Nyisztor; Monika Lakk; Zoltan Godri; Gergely Berta; Peter Geck; Robert Gabriel
TAGS: immunohistochemistry, peptides, proliferating cell nuclear antigen, retina, horizontal cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):770-778. doi: 10.1167/iovs.18-25719

Physiology and Pharmacology February 2019

1 H NMR Spectroscopy Characterization of Porcine Vitreous Humor in Physiological and Photoreceptor Degeneration Conditions

PDF

Alberto Elmi; Domenico Ventrella; Luca Laghi; Giacomo Carnevali; Chenglin Zhu; Grazia Pertile; Francesca Barone; Fabio Benfenati; Maria Laura Bacci
TAGS: photoreceptors, spectrum analysis, suidae, vitreous body, tissue degeneration, molecule
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):741-747. doi: 10.1167/iovs.18-25675

Includes: Supplemental Content

Cornea February 2019

KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27

PDF

Anil Tiwari; Sudha Swamynathan; Nicholas Alexander; John Gnalian; Shenghe Tian; Paul R. Kinchington; Shivalingappa K. Swamynathan
TAGS: signal transduction, corneal epithelium, cornea, rna, ablation, corneal epithelial cells, cyclin-dependent kinase inhibitors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):731-740. doi: 10.1167/iovs.18-26423

Includes: Supplemental Content

Biochemistry and Molecular Biology February 2019

DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B

PDF

Guangying Luo; Xia Jing; Shuai Yang; Dewei Peng; Jing Dong; Li Li; Peter S. Reinach; Dongsheng Yan
TAGS: epithelium, dna, dna methylation, wound healing, wounds and injuries, cornea, hypermethylation, dna (cytosine-5-)-methyltransferase 1, cdkn2b gene, rna, small interfering, methylation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):650-660. doi: 10.1167/iovs.18-25443

Includes: Supplemental Content

Retina February 2019

MMP Inhibition Preserves Integrin Ligation and FAK Activation to Induce Survival and Regeneration in RGCs Following Optic Nerve Damage

PDF

Philippe M. D'Onofrio; Alireza P. Shabanzadeh; Brian K. Choi; Mathias Bähr; Paulo D. Koeberle
TAGS: immunohistochemistry, integrins, axon, axotomy, injections, ligation, matrix metalloproteinases, stromelysin 1, wounds and injuries, optic nerve, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):634-649. doi: 10.1167/iovs.18-25257

Glaucoma February 2019

Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon's Capsule + Conjunctival Model

PDF

Rachel Gater; Tugce Ipek; Salman Sadiq; Dan Nguyen; Lynval Jones; Alicia El Haj; Ying Yang
TAGS: actins, tumor necrosis factors, vascular endothelial growth factor a, enzyme-linked immunosorbent assay, fibroblasts, fibrosis, glaucoma, growth factor, suidae, aqueous humor, conjunctiva, tenon's capsule, shear stress
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):605-614. doi: 10.1167/iovs.18-25335

Article February 2019

When predictions fail: Correction for extrapolation in the flash-grab effect

PDF

Tessel Blom; Qianchen Liang; Hinze Hogendoorn
TAGS: illusions, motion, perception
Journal of Vision. 2019; 19(2):3. doi: 10.1167/19.2.3

Anatomy and Pathology/Oncology February 2019

A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia

PDF

Yu Huang; Chea-su Kee; Paul M. Hocking; Cathy Williams; Shea Ping Yip; Jeremy A. Guggenheim; for The UK Biobank Eye and Vision Consortium and The CREAM Consortium
TAGS: child, genetics, myopia, refractive errors, genome-wide association study, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):559-569. doi: 10.1167/iovs.18-25597

Includes: Supplemental Content

Retinal Cell Biology February 2019

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells

PDF

Mo Wang; Lin-Ing Lau; Parameswaran G. Sreekumar; Christine Spee; David R. Hinton; Srinivas R. Sadda; Ram Kannan
TAGS: apoptosis, mitochondria, glutathione, carrier proteins, fluorescent antibody technique, mice, proteins, regulation, retinal pigment epithelium, caspase-3, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):500-516. doi: 10.1167/iovs.18-25686

Includes: Supplemental Content

Retina February 2019

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

PDF

Masaaki Kobayashi; Kazuhiro Tokuda; Yuka Kobayashi; Chiemi Yamashiro; Sho-Hei Uchi; Makoto Hatano; Kazuhiro Kimura
TAGS: fibrosis, cell motility, choroidal neovascularization, gelatin, gelatinase a, immunoblotting, mice, proteins, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):528-537. doi: 10.1167/iovs.18-25678

Retina January 2019

Exosomes Derived From Mesenchymal Stem Cells Modulate miR-126 to Ameliorate Hyperglycemia-Induced Retinal Inflammation Via Targeting HMGB1

PDF

Wei Zhang; Yang Wang; Yichun Kong
TAGS: diabetes mellitus, hyperglycemia, inflammation, glucose, retinitis, rats, stem cell, mesenchymal, exosomes, hmgb1 protein
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):294-303. doi: 10.1167/iovs.18-25617

Retina January 2019

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

PDF

Peter H. Tang; Gabriel Velez; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: mutation, exons, gelatinase a, surgical procedures, operative, vitreous body, eye, retina, cytokinesis, tissue degeneration, histopathology tests, proteolysis, proteins, splice-site mutation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):282-293. doi: 10.1167/iovs.18-25624

Includes: Supplemental Content

Biochemistry and Molecular Biology January 2019

Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers

PDF

Saima Limi; Yilin Zhao; Peng Guo; Melissa Lopez-Jones; Deyou Zheng; Robert H. Singer; Arthur I. Skoultchi; Ales Cvekl
TAGS: crystallins, lens, crystalline, lens (device), rna, messenger, mice, rna, genes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):234-244. doi: 10.1167/iovs.18-25921

Includes: Supplemental Content

Biochemistry and Molecular Biology January 2019

Critical Role of mTORC2-Akt Signaling in TGF-β1-Induced Myofibroblast Differentiation of Human Pterygium Fibroblasts

PDF

Sun Woong Kim; Hye-In Kim; Bikash Thapa; Selikem Nuwromegbe; Keunwook Lee
TAGS: signal transduction, fibroblasts, pterygium, myofibroblasts, proto-oncogene proteins c-akt, hpfs trial, mechanistic target of rapamycin complex 2, mtor serine-threonine kinases
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):82-92. doi: 10.1167/iovs.18-25376

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa

Mediators of Corneal Haze Following Implantation of Presbyopic Corneal Inlays

IMI – Myopia Genetics Report

Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation

The Neuroprotective Peptide PACAP1-38 Contributes to Horizontal Cell Development in Postnatal Rat Retina

1 H NMR Spectroscopy Characterization of Porcine Vitreous Humor in Physiological and Photoreceptor Degeneration Conditions

KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27

DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B

MMP Inhibition Preserves Integrin Ligation and FAK Activation to Induce Survival and Regeneration in RGCs Following Optic Nerve Damage

Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon's Capsule + Conjunctival Model

When predictions fail: Correction for extrapolation in the flash-grab effect

A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia

Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells

Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells by an MRTF-A Inhibitor

Exosomes Derived From Mesenchymal Stem Cells Modulate miR-126 to Ameliorate Hyperglycemia-Induced Retinal Inflammation Via Targeting HMGB1

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers

Critical Role of mTORC2-Akt Signaling in TGF-β1-Induced Myofibroblast Differentiation of Human Pterygium Fibroblasts

This feature is available to authenticated users only.

Biochemistry and Molecular Biology

To View More...

You must be signed into an individual account to use this feature.