Cornea

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Cornea January 2019

The Protective Effect of a Topical Mucin Secretagogue on Ocular Surface Damage Induced by Airborne Carbon Black Exposure

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Xiangzhe Li; Boram Kang; Youngsub Eom; Hyung Keun Lee; Hyo Myung Kim; Jong Suk Song
TAGS: western blotting, secretagogues, immunoglobulin e, eye, immunoglobulin g, cytokine, cornea, carbon, prevention, mass or substance concentration per volume, normal saline, mucins, cervical lymph node group
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):255-264. doi: 10.1167/iovs.18-25964

Cornea January 2019

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

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Cameron K. Postnikoff; Andrew D. Pucker; John Laurent; Carrie Huisingh; Gerald McGwin; Jason J. Nichols
TAGS: small cell carcinoma of lung, contact lenses, lens, crystalline, lens (device), leukocytes, eye, sclera, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):226-233. doi: 10.1167/iovs.18-24664

Cornea January 2019

Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model

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Michel M. Sun; Ann M. Chan; Samuel M. Law; Sergio Duarte; Daniel Diaz-Aguilar; Madhuri Wadehra; Lynn K. Gordon
TAGS: vascular endothelial growth factor a, epithelium, burns, corneal neovascularization, tissue membrane, antibodies, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):245-254. doi: 10.1167/iovs.18-24345

Includes: Supplemental Content

Cornea January 2019

The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium

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Abdulhakeem S. Alamri; James A. Brock; Chandana B. Herath; Indu G. Rajapaksha; Peter W. Angus; Jason J. Ivanusic
TAGS: diabetes mellitus, diabetes mellitus, type 2, common cold, cold temperature, nerve supply, cold sensation, cornea, nerve endings, nerve fibers, corneal epithelium, thermoreceptors, nociceptors, diet, high-fat
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):209-217. doi: 10.1167/iovs.18-25788

Cornea January 2019

Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro

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Sheyla González; Denise Oh; Elfren R. Baclagon; Jie J. Zheng; Sophie X. Deng
TAGS: signal transduction, stem cells, molecule, small molecule, regulation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):107-112. doi: 10.1167/iovs.18-25740

Articles January 2019

Characterization of Corneal Epithelial Cells in Keratoconus

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Rohit Shetty; Krishna Poojita Vunnava; Kamesh Dhamodaran; Himanshu Matalia; Subramani Murali; Chaitra Jayadev; Ponnulagu Murugeswari; Arkasubhra Ghosh; Debashish Das
TAGS: western blotting, keratoconus, retinal cone, corneal epithelial cells, epithelial cells, cornea, epithelium, eye
Trans. Vis. Sci. Tech.. 2019; 8(1):2. doi: 10.1167/tvst.8.1.2

Includes: Supplemental Content

Cornea January 2019

MiR-34c Participates in Diabetic Corneal Neuropathy Via Regulation of Autophagy

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Jianzhang Hu; XinYing Hu; Tong Kan
TAGS: neurons, autophagy, diabetes mellitus, neuropathy, mice, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):16-25. doi: 10.1167/iovs.18-24968

Cornea January 2019

Noninvasive Assessment of Corneal Crosslinking With Phase-Decorrelation Optical Coherence Tomography

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Brecken J. Blackburn; Shi Gu; Matthew R. Ford; Vinícius de Stefano; Michael W. Jenkins; William J. Dupps, Jr; Andrew M. Rollins
TAGS: cornea, diagnostic imaging, eye, intraocular pressure, glycerol, motion, suidae, optical coherence tomography, corneal collagen cross-linking
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):41-51. doi: 10.1167/iovs.18-25535

Articles December 2018

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

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Peng Xu; Chifune Kai; Satoshi Kawasaki; Yuki Kobayashi; Kouji Yamamoto; Motokazu Tsujikawa; Ryuhei Hayashi; Kohji Nishida
TAGS: proteins, epcam gene, corneal epithelial cells, antibodies, epithelial cell adhesion molecule, genes, epithelium, cornea
Trans. Vis. Sci. Tech.. 2018; 7(6):30. doi: 10.1167/tvst.7.6.30

Cornea December 2018

Prevention of Corneal Neovascularization by Adenovirus Encoding Human Vascular Endothelial Growth Factor Soluble Receptor (s-VEGFR1) in Lacrimal Gland

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Luis Fernando Nominato; Ana Carolina Dias; Lara Cristina Dias; Marina Zilio Fantucci; Lilian Eslaine Costa Mendes da Silva; Adriana de Andrade Murashima; Eduardo Melani Rocha
TAGS: cytokine, vascular endothelial growth factor a, gene therapy, corneal neovascularization, eye diseases, body tissue, cornea, lacrimal gland, prevention, alkalies, burns, choroidal neovascularization, adenoviruses, bodily secretions, langer-giedion syndrome, rna, messenger, adenoviral vector, normal saline
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6036-6044. doi: 10.1167/iovs.17-22322

Includes: Supplemental Content

Immunology and Microbiology December 2018

Mechanism of Pseudomonas aeruginosa Small Protease (PASP), a Corneal Virulence Factor

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Aihua Tang; Armando R. Caballero; Mary E. Marquart; Michael A. Bierdeman; Richard J. O'Callaghan
TAGS: pseudomonas aeruginosa, mutation, catalysis, cornea, serine proteases, virulence factors, proteolytic enzymes, proteins, endopeptidases
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5993-6002. doi: 10.1167/iovs.18-25834

Cornea December 2018

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

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Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: hyperglycemia, diabetes mellitus, type 1, body weight, alloxan, neurons, streptozocin, sural nerve, cornea, mice, nerve lesions
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5868-5875. doi: 10.1167/iovs.18-25693

Biochemistry and Molecular Biology December 2018

Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease

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Anastasia Marie Litke; Sarah Samuelson; Kerry R. Delaney; Yves Sauvé; Robert L. Chow
TAGS: mutation, corneal diseases, electroretinography, keratoconus, luciferases, missense mutation, cornea, diagnostic imaging, mice, pathogenicity
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5824-5835. doi: 10.1167/iovs.18-25490

Includes: Supplemental Content

Retina December 2018

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

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Gerard A. Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; Lisa M. Hernandez; James Burke; Keith A. Luhrs; Thomas C. Hohman
TAGS: angiogenesis, vascular endothelial growth factor a, oryctolagus cuniculus, bevacizumab, ranibizumab, affinity, aflibercept, anti-vascular endothelial growth factor therapy, vascular permeability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5836-5846. doi: 10.1167/iovs.18-25307

Clinical and Epidemiologic Research December 2018

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

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Cecilia Chao; Lakshmi Akileswaran; Jessica N. Cooke Bailey; Mark Willcox; Russell Van Gelder; Carol Lakkis; Fiona Stapleton; Kathryn Richdale
TAGS: cytokine, environmental factors, contact lenses, genotype, cornea, interleukin-6, microbiome, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5752-5761. doi: 10.1167/iovs.18-24845

Includes: Supplemental Content

Cornea November 2018

The Chemokine Receptor CXCR4 Mediates Recruitment of CD11c + Conventional Dendritic Cells Into the Inflamed Murine Cornea

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Maria J. Lopez; Yashar Seyed-Razavi; Arsia Jamali; Deshea L. Harris; Pedram Hamrah
TAGS: centers for disease control and prevention (u.s.), dendritic cells, cornea, mice, stromal cell-derived factor 1, cxcr4 receptors, chemokine receptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5671-5681. doi: 10.1167/iovs.18-25084

Includes: Supplemental Content

Cornea November 2018

Downregulation of IL-7 and IL-7R Reduces Membrane-Type Matrix Metalloproteinase 14 in Granular Corneal Dystrophy Type 2 Keratocyte

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So Young Kim; Areum Yeo; Hyemi Noh; Yong Woo Ji; Jong Suk Song; Hyeon Chang Kim; Lark Kyun Kim; Hyung Keun Lee
TAGS: matrix metalloproteinases, keratocytes, interleukin-7, hereditary corneal dystrophy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5693-5703. doi: 10.1167/iovs.18-25161

Includes: Supplemental Content

Articles November 2018

Comparison of Artificial Anterior Chamber Internal Pressures and Cutting Systems for Descemet's Stripping Automated Endothelial Keratoplasty

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Sota Nishisako; Dai Aoki; Chiaki Sasaki; Kazunari Higa; Jun Shimazaki
TAGS: endothelial cells, anterior chamber of eye, keratoplasty, endothelium, tissue transplants, cornea, pressure-physical agent, significance, descemet stripping endothelial keratoplasty, donors
Trans. Vis. Sci. Tech.. 2018; 7(6):11. doi: 10.1167/tvst.7.6.11

Special Issue November 2018

Tear Film–Oriented Diagnosis and Tear Film–Oriented Therapy for Dry Eye Based on Tear Film Dynamics

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Norihiko Yokoi; Georgi As Georgiev
TAGS: epithelium, dry eye syndromes, fluorescein, mucins, signs and symptoms, eye, eyedrops, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2018; 59(14):DES13-DES22. doi: 10.1167/iovs.17-23700

Special Issue November 2018

Irregular Astigmatism and Higher-Order Aberrations in Eyes With Dry Eye Disease

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Shizuka Koh
TAGS: astigmatism, dry eye syndromes, optics, cornea, eye, tear film finding, quality
Invest. Ophthalmol. Vis. Sci.. 2018; 59(14):DES36-DES40. doi: 10.1167/iovs.17-23500

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The Protective Effect of a Topical Mucin Secretagogue on Ocular Surface Damage Induced by Airborne Carbon Black Exposure

Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers

Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model

The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium

Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro

Characterization of Corneal Epithelial Cells in Keratoconus

MiR-34c Participates in Diabetic Corneal Neuropathy Via Regulation of Autophagy

Noninvasive Assessment of Corneal Crosslinking With Phase-Decorrelation Optical Coherence Tomography

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

Prevention of Corneal Neovascularization by Adenovirus Encoding Human Vascular Endothelial Growth Factor Soluble Receptor (s-VEGFR1) in Lacrimal Gland

Mechanism of Pseudomonas aeruginosa Small Protease (PASP), a Corneal Virulence Factor

Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes

Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

The Chemokine Receptor CXCR4 Mediates Recruitment of CD11c + Conventional Dendritic Cells Into the Inflamed Murine Cornea

Downregulation of IL-7 and IL-7R Reduces Membrane-Type Matrix Metalloproteinase 14 in Granular Corneal Dystrophy Type 2 Keratocyte

Comparison of Artificial Anterior Chamber Internal Pressures and Cutting Systems for Descemet's Stripping Automated Endothelial Keratoplasty

Tear Film–Oriented Diagnosis and Tear Film–Oriented Therapy for Dry Eye Based on Tear Film Dynamics

Irregular Astigmatism and Higher-Order Aberrations in Eyes With Dry Eye Disease

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