Cornea

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Articles July 2019

Corneal Curvature: the Influence of Corneal Accommodation and Biomechanics on Corneal Shape

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Henry B. Wallace; James McKelvie; Colin R. Green; Stuti L. Misra
TAGS: cornea, visual accommodation, biomechanics, shape
Trans. Vis. Sci. Tech.. 2019; 8(4):5. doi: 10.1167/tvst.8.4.5

Cornea July 2019

Effects of Tear Film Instability on Sensory Responses to Corneal Cold, Mechanical, and Chemical Stimuli

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Ping Situ; Carolyn G. Begley; Trefford L. Simpson
TAGS: cold temperature, cornea, tear film finding, sensory perception, signs and symptoms, pain, common cold
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2935-2941. doi: 10.1167/iovs.19-27298

Cornea July 2019

Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye

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Bowen Wang; Lulu Peng; Hong Ouyang; Li Wang; Dalian He; Jing Zhong; Yichen Xiao; Yuqing Deng; Meng Li; Saiqun Li; Jin Yuan
TAGS: autophagy, dry eye syndromes, oxidative stress, western blotting, stress, mice, cell survival
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2836-2847. doi: 10.1167/iovs.19-27072

Includes: Supplemental Content

Cornea July 2019

Inhibition by Epigallocatechin Gallate of IL-1–Induced Urokinase-Type Plasminogen Activator Expression and Collagen Degradation by Corneal Fibroblasts

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Koji Sugioka; Koji Yoshida; Junko Murakami; Motoki Itahashi; Hiroshi Mishima; Teruo Nishida; Shunji Kusaka
TAGS: catabolism, collagen, cornea, fibroblasts, urokinase, interleukin-1, plasmin
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2895-2903. doi: 10.1167/iovs.19-27306

Articles June 2019

Quantitative Discrimination of Healthy and Diseased Corneas With Second Harmonic Generation Microscopy

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Francisco J. Ávila; Pablo Artal; Juan M. Bueno
TAGS: collagen, cornea, harmonics, second harmonic generation microscopy
Trans. Vis. Sci. Tech.. 2019; 8(3):51. doi: 10.1167/tvst.8.3.51

Cornea June 2019

The Effects of Aging on Corneal and Ocular Surface Homeostasis in Mice

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Manikkuwadura Eranda Harshan De Silva; Lisa J. Hill; Laura E. Downie; Holly R. Chinnery
TAGS: cornea, mice, aging, neurons
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2705-2715. doi: 10.1167/iovs.19-26631

Includes: Supplemental Content

Cornea June 2019

Expression and Role of Nucleotide-Binding Oligomerization Domain 2 (NOD2) in the Ocular Surface of Murine Dry Eye

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Ying Li; Rujun Jin; Lan Li; Hyeon Jeong Yoon; Joo-Hee Choi; Jong-Hwan Park; Zuguo Liu; Wei Li; Zhengri Li; Kyung Chul Yoon
TAGS: body tissue, conjunctiva, cornea, dry eye syndromes, mice, nucleotides, cytokine, in situ nick-end labeling, ripk2 gene, interleukin-6, stress, tumor necrosis factors, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2641-2649. doi: 10.1167/iovs.19-27144

Clinical Trials June 2019

Effects of the Glaucoma Drugs Latanoprost and Brimonidine on Corneal Temperature

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Katarzyna Konieczka; Simone Koch; Daniela Hauenstein; Thomas Navin Chackathayil; Tatjana Binggeli; Andreas Schoetzau; Josef Flammer
TAGS: brimonidine, latanoprost, antiglaucoma medications, cornea, temperature
Trans. Vis. Sci. Tech.. 2019; 8(3):47. doi: 10.1167/tvst.8.3.47

Cornea June 2019

Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye

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Pooja Khamar; Archana Padmanabhan Nair; Rohit Shetty; Tanuja Vaidya; Murali Subramani; Murugeswari Ponnalagu; Kamesh Dhamodaran; Sharon D'souza; Anuprita Ghosh; Natasha Pahuja; Rashmi Deshmukh; Prerna Ahuja; Kanchan Sainani; Rudy M. M. A. Nuijts; Debashish Das; Arkasubhra Ghosh; Swaminathan Sethu
TAGS: cornea, dendritic cells, dry eye syndromes, pain perception, signs and symptoms, vitamin d
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2532-2542. doi: 10.1167/iovs.19-26914

Includes: Supplemental Content

Review June 2019

Efficacy of Different Procedures of Intra-Corneal Ring Segment Implantation in Keratoconus: a Systematic Review and Meta-Analysis

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Cédric Benoist d'Azy; Bruno Pereira; Frédéric Chiambaretta; Frédéric Dutheil
TAGS: cornea, corneal collagen cross-linking, implantation procedure, ion cyclotron resonance spectrometry, keratoconus, meta-analysis, systematic reviews
Trans. Vis. Sci. Tech.. 2019; 8(3):38. doi: 10.1167/tvst.8.3.38

Includes: Supplemental Content

Articles June 2019

Automatic Segmentation of Corneal Microlayers on Optical Coherence Tomography Images

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Amr Elsawy; Mohamed Abdel-Mottaleb; Ibrahim-Osama Sayed; Dan Wen; Vatookarn Roongpoovapatr; Taher Eleiwa; Ahmed M. Sayed; Mariam Raheem; Gustavo Gameiro; Mohamed Abou Shousha
TAGS: cornea, datasets, optical coherence tomography, pixel, artifacts
Trans. Vis. Sci. Tech.. 2019; 8(3):39. doi: 10.1167/tvst.8.3.39

Articles June 2019

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

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Young Hyun Kim; Andrew D. Graham; Wing Li; Clayton J. Radke; Meng C. Lin
TAGS: evaporation, eye, heterogeneity of variance, loa, sample size, tear production, dry eye syndromes, humidity, reading (activity), anesthetics, clinical trial protocol document, body temperature
Trans. Vis. Sci. Tech.. 2019; 8(3):40. doi: 10.1167/tvst.8.3.40

Article June 2019

Binocular cross-correlation analyses of the effects of high-order aberrations on the stereoacuity of eyes with keratoconus

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Sangeetha Metlapally; Shrikant R. Bharadwaj; Austin Roorda; Vinay Kumar Nilagiri; Tiffanie T. Yu; Clifton M. Schor
TAGS: eye, keratoconus, optics, point spread function, health disparity
Journal of Vision. 2019; 19(6):12. doi: 10.1167/19.6.12

Cornea June 2019

Remodeling of Substance P Sensory Nerves and Transient Receptor Potential Melastatin 8 (TRPM8) Cold Receptors After Corneal Experimental Surgery

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Jiucheng He; Thang Luong Pham; Azucena H. Kakazu; Haydee E. P. Bazan
TAGS: cornea, neurons, substance p, surgical procedures, operative, wounds and injuries, operative procedure on cornea, epithelium, cold temperature, sensory nerves, corneal injuries, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2449-2460. doi: 10.1167/iovs.18-26384

Includes: Multimedia, Supplemental Content

Articles June 2019

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

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Anup Kumar Ghosh; Shivaprakash Mandya Rudramurthy; Amit Gupta; Hansraj Choudhary; Shreya Singh; Anchal Thakur; Manu Jatana
TAGS: amphotericin b, antifungal agents, cornea, did not receive therapy or drug, fungal keratitis, liposomes, oryctolagus cuniculus, keratitis
Trans. Vis. Sci. Tech.. 2019; 8(3):35. doi: 10.1167/tvst.8.3.35

Articles June 2019

Tracking the Reflective Light Particles Spreading on the Cornea: An Emerging Assessment for Tear Film Homeostasis

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Hung-Yin Lai; Ming-Tse Kuo; Po-Chiung Fang; Chi-Chang Lin; Chun-Chih Chien; Wan-Hua Cho; Alexander Chen; Ing-Chou Lai
TAGS: homeostasis, cornea, tear film finding, liposomal amikacin for inhalation
Trans. Vis. Sci. Tech.. 2019; 8(3):32. doi: 10.1167/tvst.8.3.32

Includes: Multimedia, Supplemental Content

Cornea June 2019

Magnetic Human Corneal Endothelial Cell Transplant: Delivery, Retention, and Short-Term Efficacy

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Xin Xia; Melissa Atkins; Roopa Dalal; Olga Kuzmenko; Kun-Che Chang; Catalina B. Sun; C. Andres Benatti; Dillon J. Rak; Michael Nahmou; Noelia J. Kunzevitzky; Jeffrey L. Goldberg
TAGS: endothelial cells, oryctolagus cuniculus, cornea, transplantation, cell therapy, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2438-2448. doi: 10.1167/iovs.18-26001

Includes: Supplemental Content

Articles May 2019

Extracellular Matrix Protein Coating of Processed Fish Scales Improves Human Corneal Endothelial Cell Adhesion and Proliferation

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Yi-Jen Hsueh; David Hui-Kang Ma; Kathleen Sheng-Chuan Ma; Tze-Kai Wang; Cheng-Hung Chou; Chien-Cheng Lin; Min-Chang Huang; Li-Jyuan Luo; Jui-Yang Lai; Hung-Chi Chen
TAGS: cell proliferation, endothelial cells, extracellular matrix proteins, adhesions, cornea, proteins, weight measurement scales
Trans. Vis. Sci. Tech.. 2019; 8(3):27. doi: 10.1167/tvst.8.3.27

Includes: Supplemental Content

Articles May 2019

Representation of Central Endothelial Cell Density by Analysis of Single Best Specular Microscopy Image Regardless of Cell Size Variance

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Yue Shi; Jianyan Huang; Elmira Baghdasaryan; Ping Huang; Xiwen Huang; Srinivas R. Sadda; Olivia L. Lee
TAGS: endothelial cells, cell size, cornea, eye, heterogeneity of variance
Trans. Vis. Sci. Tech.. 2019; 8(3):23. doi: 10.1167/tvst.8.3.23

Cornea May 2019

A Mathematical Model of Corneal Metabolism in the Presence of an Iris-Fixated Phakic Intraocular Lens

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Peyman Davvalo Khongar; Jan O. Pralits; Xi Cheng; Peter Pinsky; Paolo Soleri; Rodolfo Repetto
TAGS: metabolism, glucose, anterior chamber of eye, biological transport, eyelid, lactates, cornea, intraocular lens implant device, mass or substance concentration per volume, mathematical model, iris fixation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2311-2320. doi: 10.1167/iovs.19-26624

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Corneal Curvature: the Influence of Corneal Accommodation and Biomechanics on Corneal Shape

Effects of Tear Film Instability on Sensory Responses to Corneal Cold, Mechanical, and Chemical Stimuli

Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye

Inhibition by Epigallocatechin Gallate of IL-1–Induced Urokinase-Type Plasminogen Activator Expression and Collagen Degradation by Corneal Fibroblasts

Quantitative Discrimination of Healthy and Diseased Corneas With Second Harmonic Generation Microscopy

The Effects of Aging on Corneal and Ocular Surface Homeostasis in Mice

Expression and Role of Nucleotide-Binding Oligomerization Domain 2 (NOD2) in the Ocular Surface of Murine Dry Eye

Effects of the Glaucoma Drugs Latanoprost and Brimonidine on Corneal Temperature

Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye

Efficacy of Different Procedures of Intra-Corneal Ring Segment Implantation in Keratoconus: a Systematic Review and Meta-Analysis

Automatic Segmentation of Corneal Microlayers on Optical Coherence Tomography Images

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

Binocular cross-correlation analyses of the effects of high-order aberrations on the stereoacuity of eyes with keratoconus

Remodeling of Substance P Sensory Nerves and Transient Receptor Potential Melastatin 8 (TRPM8) Cold Receptors After Corneal Experimental Surgery

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

Tracking the Reflective Light Particles Spreading on the Cornea: An Emerging Assessment for Tear Film Homeostasis

Magnetic Human Corneal Endothelial Cell Transplant: Delivery, Retention, and Short-Term Efficacy

Extracellular Matrix Protein Coating of Processed Fish Scales Improves Human Corneal Endothelial Cell Adhesion and Proliferation

Representation of Central Endothelial Cell Density by Analysis of Single Best Specular Microscopy Image Regardless of Cell Size Variance

A Mathematical Model of Corneal Metabolism in the Presence of an Iris-Fixated Phakic Intraocular Lens

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