Cornea

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Articles October 2019

Prolonged Duration Topical Corneal Anesthesia With the Cationic Lidocaine Derivative QX-314

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Alan G. Woodruff; Claudia M. Santamaria; Manisha Mehta; Grant L. Pemberton; Kathleen Cullion; Daniel S. Kohane
TAGS: cornea, lidocaine, qx-314
Trans. Vis. Sci. Tech.. 2019; 8(5):28. doi: 10.1167/tvst.8.5.28

Physiology and Pharmacology October 2019

The Effects of High Lighting on the Development of Form-Deprivation Myopia in Guinea Pigs

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Luoli Zhang; Xiaomei Qu
TAGS: caviidae, eye, lighting, myopia, refraction, cornea, biometry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4319-4327. doi: 10.1167/iovs.18-25258

Includes: Supplemental Content

Cornea October 2019

Stimulation of Phagocytic Activity in Cultured Human Corneal Fibroblasts by Plasminogen

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Tomoko Sato; Koji Sugioka; Aya Kodama-Takahashi; Junko Murakami; Akio Saito; Hiroshi Mishima; Teruo Nishida; Shunji Kusaka
TAGS: cornea, fibroblasts, plasminogen, phagocytosis, cell-derived microparticles
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4205-4214. doi: 10.1167/iovs.19-27736

Cornea October 2019

Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide

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Changjun Wang; Laura Schaefer; Fang Bian; Zhiyuan Yu; Stephen C. Pflugfelder; Robert A. Britton; Cintia S. de Paiva
TAGS: antibiotics, dysbiosis, inflammatory response, mice, microbiome, conjunctiva, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4224-4233. doi: 10.1167/iovs.19-27939

Cornea October 2019

Changes in Corneal Detection Thresholds After Repeated Tear Film Instability

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Deborah Awisi-Gyau; Carolyn G. Begley; Ping Situ; Trefford L. Simpson
TAGS: cornea, signs and symptoms, tear film finding, pain
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4234-4240. doi: 10.1167/iovs.19-27802

Cornea October 2019

Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

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Kiyokazu Ozaki; Yui Terayama; Tetsuro Matsuura
TAGS: cornea, hyperglycemia, neurons, rats, sensory nerves, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4151-4158. doi: 10.1167/iovs.19-28060

Glaucoma October 2019

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

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Kyoung Min Lee; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari; Robert N. Weinreb
TAGS: cornea, corneal hysteresis, cribriform plate, genu varum, open-angle glaucoma, eye, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4171-4177. doi: 10.1167/iovs.19-27087

Includes: Supplemental Content

Cornea October 2019

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

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Xiaowen Lu; Mitchell A. Watsky
TAGS: corneal epithelial cells, corneal epithelium, desmosomes, hemidesmosomes, integrins, mice, proteins, vitamin d, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4074-4083. doi: 10.1167/iovs.19-27796

Includes: Supplemental Content

Physiology and Pharmacology September 2019

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

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Munetoyo Toda; Hiroshi Yukawa; Jun Yamada; Morio Ueno; Shigeru Kinoshita; Yoshinobu Baba; Junji Hamuro
TAGS: anterior chamber of eye, cornea, endothelial cells, eye, fluorescence, mice, quantum dots, diagnostic imaging, injections
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4008-4020. doi: 10.1167/iovs.19-27788

Includes: Supplemental Content

Immunology and Microbiology September 2019

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

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Steffani Fitzpatrick; Robert Lausch; Robert A. Barrington
TAGS: cornea, human herpesvirus 1, infection, t-lymphocytes, mice, interleukin-17
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3952-3962. doi: 10.1167/iovs.19-27810

Cornea September 2019

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

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Ziye Rong; Jiaxin Hu; David R. Corey; V. Vinod Mootha
TAGS: proteins, rna, cornea, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3980-3991. doi: 10.1167/iovs.19-27641

Includes: Supplemental Content

Articles September 2019

In Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability

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Wayne Heaselgrave; Anas Hamad; Steven Coles; Scott Hau
TAGS: acanthamoeba, cysts, ophthalmic agents, trophozoite, bronchioloalveolar carcinoma, toxic effect
Trans. Vis. Sci. Tech.. 2019; 8(5):17. doi: 10.1167/tvst.8.5.17

Cornea September 2019

The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells

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Yun Zhang; Fukang Yuan; Lin Liu; Zufeng Chen; Xiaoyun Ma; Zhen Lin; Jun Zou
TAGS: corneal epithelial cells, epithelium, phenotype, wound healing, hypoxia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3854-3862. doi: 10.1167/iovs.19-27013

Cornea September 2019

Relations Among Corneal Curvature, Thickness, and Volume in Keratoconus as Evaluated by Anterior Segment–Optical Coherence Tomography

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Naoyuki Morishige; Kazuyoshi Magome; Akifumi Ueno; Taka-Aki Matsui; Teruo Nishida
TAGS: cicatrix, cornea, keratoconus, optical coherence tomography, volume, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3794-3802. doi: 10.1167/iovs.19-27619

Includes: Supplemental Content

Cornea September 2019

Therapeutic Effects of STAT3 Inhibition on Experimental Murine Dry Eye

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Mingli Qu; Xia Qi; Qian Wang; Lei Wan; Jing Li; Wei Li; Yingli Li; Qingjun Zhou
TAGS: dry eye syndromes, mice, stat3 protein
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3776-3785. doi: 10.1167/iovs.19-26928

Articles September 2019

A Method to Calibrate the Carbon Dioxide (Chemical) Stimuli of Pneumatic Esthesiometer Externally

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Varadharajan Jayakumar; Trefford L. Simpson
TAGS: carbon dioxide, sensor, unit of flow rate, mass or substance concentration per volume
Trans. Vis. Sci. Tech.. 2019; 8(5):4. doi: 10.1167/tvst.8.5.4

Articles September 2019

Characterization of Corneal Biomechanical Properties and Determination of Natural Intraocular Pressure Using CID-GAT

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Shu-Hao Lu; I. T. Chong; Stanley Y. Y. Leung; David C. C. Lam
TAGS: collision-induced dissociation, cornea, intraocular pressure, eye
Trans. Vis. Sci. Tech.. 2019; 8(5):10. doi: 10.1167/tvst.8.5.10

Cornea September 2019

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

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Hyun Jung Lee; Soojung Shin; Seul-Gi Yoon; Eun Jeong Cheon; So-Hyang Chung
TAGS: animal model, chloroquine, dry eye syndromes, mice, sjogren's syndrome, syndrome, autophagy, sjogren's syndrome a antibody, phenotype, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3708-3716. doi: 10.1167/iovs.19-27469

Includes: Supplemental Content

Cornea September 2019

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

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Kazunari Higa; Junko Higuchi; Reona Kimoto; Yoshiyuki Satake; Takefumi Yamaguchi; Daisuke Tomida; Jun Shimazaki
TAGS: amnion, cornea, corneal epithelium, epithelium, fibroblasts, wound healing, oryctolagus cuniculus, antibodies, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3718-3726. doi: 10.1167/iovs.19-27041

Articles September 2019

Development of an Eye Model With a Physiological Blink Mechanism

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Chau-Minh Phan; Hendrik Walther; Han Qiao; Ram Shinde; Lyndon Jones
TAGS: eye, eyelid
Trans. Vis. Sci. Tech.. 2019; 8(5):1. doi: 10.1167/tvst.8.5.1

Includes: Multimedia, Supplemental Content

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Prolonged Duration Topical Corneal Anesthesia With the Cationic Lidocaine Derivative QX-314

The Effects of High Lighting on the Development of Form-Deprivation Myopia in Guinea Pigs

Stimulation of Phagocytic Activity in Cultured Human Corneal Fibroblasts by Plasminogen

Dysbiosis Modulates Ocular Surface Inflammatory Response to Liposaccharide

Changes in Corneal Detection Thresholds After Repeated Tear Film Instability

Hyperglycemia Suppresses Age-Related Increases in Corneal Peripheral Sensory Nerves in Wistar Bon Kobori (WBN/Kob) Rats

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

Influence of Vitamin D on Corneal Epithelial Cell Desmosomes and Hemidesmosomes

In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

In Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability

The Role of the miR-21/SPRY2 Axis in Modulating Proangiogenic Factors, Epithelial Phenotypes, and Wound Healing in Corneal Epithelial Cells

Relations Among Corneal Curvature, Thickness, and Volume in Keratoconus as Evaluated by Anterior Segment–Optical Coherence Tomography

Therapeutic Effects of STAT3 Inhibition on Experimental Murine Dry Eye

A Method to Calibrate the Carbon Dioxide (Chemical) Stimuli of Pneumatic Esthesiometer Externally

Characterization of Corneal Biomechanical Properties and Determination of Natural Intraocular Pressure Using CID-GAT

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

Effects of Amniotic Membrane–Derived Fibroblast Supernatant on Corneal Epithelium

Development of an Eye Model With a Physiological Blink Mechanism

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