Eye Anatomy and Disorders

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Retina January 2025

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

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Brandon D. Anderson; Brent A. Bell; Ying Song; Timothy T. Lee; Tan Wang; Joshua L. Dunaief
TAGS: age-related macular degeneration, nonexudative, atrophy, injections, iodates, sodium, mice, diagnostic imaging, retina
Trans. Vis. Sci. Tech.. 2025; 14(1):9. https://doi.org/10.1167/tvst.14.1.9

Includes: Supplemental Content

Public Health January 2025

Social Determinants of Uncorrected Distance and Near Visual Impairment in an Older Adult Population

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Po-Jen Lin; Alison G. Abraham; Pradeep Ramulu; Aleks Mihailovic; Anna Kucharska-Newton; Xinxing Guo
TAGS: community, eye, older adult, social determinants of health, visual impairment, physicians, aric trial, health, income
Trans. Vis. Sci. Tech.. 2025; 14(1):8. https://doi.org/10.1167/tvst.14.1.8

Includes: Supplemental Content

Retina January 2025

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

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Federico Corti; Filippo Locri; Flavia Plastino; Paola Perrotta; Krisztina Zsebo; Emma Ristori; Xiangyun Yin; Eric Song; Helder André; Michael Simons
TAGS: antibodies, choroidal neovascularization, edema, inflammation, lasers, mice, syndecan, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, intravitreal injections
Trans. Vis. Sci. Tech.. 2025; 14(1):10. https://doi.org/10.1167/tvst.14.1.10

Includes: Supplemental Content

Cornea January 2025

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease

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Ling Wang; Ye Tian; Hui Zhang; Yongxiao Dong; Xia Hua; Xiaoyong Yuan
TAGS: caspase-3, cornea, dry eye syndromes, epithelium, mice, proteins, pyroptosis, apoptosis, genes, western blotting
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):24. https://doi.org/10.1167/iovs.66.1.24

Includes: Supplemental Content

Lens January 2025

Mechanical Properties of Eye Lens Cortical and Nuclear Membranes and the Whole Lens

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Nawal K. Khadka; Dieter Haemmerle; Paul H. Davis; Laxman Mainali
TAGS: lens (device), lens, crystalline, nuclear envelope, tissue membrane, cattle, lipids
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):27. https://doi.org/10.1167/iovs.66.1.27

Retina January 2025

Retinal Sensitivity in KCNV2 -Associated Retinopathy

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Thales A. C. de Guimaraes; Isabela M. C. de Guimaraes; Manickam Nick Muthiah; Angelos Kalitzeos; Michel Michaelides
TAGS: retinal diseases, visual acuity, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):26. https://doi.org/10.1167/iovs.66.1.26

Letters to the Editor January 2025

Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?

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Blondy Kayembe Mulumba; Karen Leffondré; Pierre Joly; Marie-Noëlle Delyfer; Cécile Delcourt
TAGS: age-related macular degeneration, genetics, statins
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):25. https://doi.org/10.1167/iovs.66.1.25

Cornea January 2025

Mustard Gas Induced Corneal Injury Involves Ferroptosis and p38 MAPK Signaling

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Nishant R. Sinha; Alexandria C. Hofmann; Laila A. Suleiman; Maxwell T. Jeffrey; William C. Jeffrey; Rajnish Kumar; Ratnakar Tripathi; Rajiv R. Mohan
TAGS: corneal injuries, ferroptosis, mitogen-activated protein kinase p38, mustard gas, signal transduction, cornea
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):23. https://doi.org/10.1167/iovs.66.1.23

Includes: Supplemental Content

Biochemistry and Molecular Biology January 2025

PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3

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Qiongjie Cao; Wenji Xu; Xiaoyan Chen; Guangying Luo; Peter S. Reinach; Dongsheng Yan
TAGS: arginine, cornea, epigenetics, epithelium, methylation, wound healing, regulation, mice, western blotting, histones
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):22. https://doi.org/10.1167/iovs.66.1.22

Includes: Supplemental Content

Cornea January 2025

Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns

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Chun-Hsiang Chang; I-Chen Peng; Yi-Hsun Huang
TAGS: alkalies, burns, cornea, macrophage activation, thrombomodulin, wound healing
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):21. https://doi.org/10.1167/iovs.66.1.21

Cornea January 2025

miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients

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Mahsa Nastaranpour; Shweta Suiwal; Tanja Stachon; Fabian N. Fries; Maryam Amini; Berthold Seitz; Eckart Meese; Nicole Ludwig; Nóra Szentmáry
TAGS: aniridia, epithelial cells, micrornas, candidate disease gene
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):20. https://doi.org/10.1167/iovs.66.1.20

Includes: Supplemental Content

Article January 2025

Eye posture and screen alignment with simulated see-through head-mounted displays

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Agostino Gibaldi; Yinghua Liu; Christos Kaspiris-Rousellis; Madhumitha S. Mahadevan; Jenny C. A. Read; Björn N. S. Vlaskamp; Gerrit W. Maus
TAGS: eye, posture
Journal of Vision. 2025; 25(1):9. https://doi.org/10.1167/jov.25.1.9

Includes: Supplemental Content

Article January 2025

Target interception in virtual reality is better for natural versus unnatural trajectory shapes and orientations

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Sofia Varon; Karsten Babin; Miriam Spering; Jody C. Culham
TAGS: shape, virtual reality, visual fields, reaction time, motion, movement time
Journal of Vision. 2025; 25(1):11. https://doi.org/10.1167/jov.25.1.11

Includes: Supplemental Content

Retina January 2025

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

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Shuqi You; Suqian Wu; Shicheng Yang; Zhenyang Zhao; Wei Chen; Xiangwu Chen; Huan Wang; Qing Xia; Jiawei Xiong; Hongsheng Zhou; Xiaofen Mo
TAGS: drug delivery systems, pus, sclera, ultrasonography, nipple discharge aspiration, sodium fluoride
Trans. Vis. Sci. Tech.. 2025; 14(1):7. https://doi.org/10.1167/tvst.14.1.7

Includes: Supplemental Content

Artificial Intelligence January 2025

Conjunctival Bulbar Redness Extraction Pipeline for High-Resolution Ocular Surface Photography

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Philipp Ostheimer; Arno Lins; Lars Albert Helle; Vito Romano; Bernhard Steger; Marco Augustin; Daniel Baumgarten
TAGS: conjunctiva, datasets, eye, iris, ocular surfaces, photography, diagnostic imaging
Trans. Vis. Sci. Tech.. 2025; 14(1):6. https://doi.org/10.1167/tvst.14.1.6

Retina January 2025

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

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Shizhen Lei; Yani Liu
TAGS: gastrointestinal microbiome, genetic correlation analysis, genetics, mendelian randomization analysis, retinal vein occlusion
Trans. Vis. Sci. Tech.. 2025; 14(1):5. https://doi.org/10.1167/tvst.14.1.5

Includes: Supplemental Content

Anatomy and Pathology/Oncology January 2025

Leptin Receptor Deficiency–Associated Diabetes Disrupts Lacrimal Gland Circadian Rhythms and Contributes to Dry Eye Syndrome

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Xiaoting Pei; Mengru Ba; Tingting Yang; Shuting Xuan; Duliurui Huang; Di Qi; Dingli Lu; Shenzhen Huang; Zhijie Li
TAGS: diabetes mellitus, diabetes mellitus, type 2, insulin, mice, langer-giedion syndrome, circadian rhythms, dry eye syndromes, gene expression
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):19. https://doi.org/10.1167/iovs.66.1.19

Includes: Supplemental Content

Glaucoma January 2025

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

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Daniel Kim; Raymond Fang; Pengpeng Zhang; Zihang Yan; Cheng Sun; Guorong Li; Christa Montgomery; Simon W. M. John; W. Daniel Stamer; Hao F. Zhang; C. Ross Ethier
TAGS: anterior chamber of eye, aqueous humor, diagnostic imaging, eye, mice, vaccine information sheets, volume, x-ray microtomography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):18. https://doi.org/10.1167/iovs.66.1.18

Includes: Supplemental Content

Retina January 2025

Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment

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Lisong Wang; Gaocheng Zou; Yuanye Yan; Ronghua Shi; Yue Guo; Mei Zhang; Li Lu; Kai Dong
TAGS: idebenone, mice, oxidative phosphorylation defect, photoreceptors, retinal detachment, body tissue, mitochondria, retina, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):17. https://doi.org/10.1167/iovs.66.1.17

Includes: Supplemental Content

Low Vision Rehabilitation January 2025

Performance on Activities of Daily Living and User Experience When Using Artificial Intelligence by Individuals With Vision Impairment

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William Seiple; Hilde P. A. van der Aa; Fernanda Garcia-Piña; Izekiel Greco; Calvin Roberts; Ruth van Nispen
TAGS: activities of daily living, artificial intelligence, blindness, visual impairment, perception
Trans. Vis. Sci. Tech.. 2025; 14(1):3. https://doi.org/10.1167/tvst.14.1.3

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Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

Social Determinants of Uncorrected Distance and Near Visual Impairment in an Older Adult Population

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease

Mechanical Properties of Eye Lens Cortical and Nuclear Membranes and the Whole Lens

Retinal Sensitivity in KCNV2 -Associated Retinopathy

Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?

Mustard Gas Induced Corneal Injury Involves Ferroptosis and p38 MAPK Signaling

PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3

Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns

miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients

Eye posture and screen alignment with simulated see-through head-mounted displays

Target interception in virtual reality is better for natural versus unnatural trajectory shapes and orientations

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

Conjunctival Bulbar Redness Extraction Pipeline for High-Resolution Ocular Surface Photography

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

Leptin Receptor Deficiency–Associated Diabetes Disrupts Lacrimal Gland Circadian Rhythms and Contributes to Dry Eye Syndrome

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment

Performance on Activities of Daily Living and User Experience When Using Artificial Intelligence by Individuals With Vision Impairment

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