Imaging

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Multidisciplinary Ophthalmic Imaging March 2025

Three-Dimensional β-Amyloid Burden Correlation Between the Eye and Brain in Alzheimer's Disease Mice Using Light-Sheet Fluorescence Microscopy

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Hye Joo Son; Seonok Kim; Seog-Young Kim; Jin Hwa Jung; Suk Hyun Lee; Soo-Jong Kim; Chanwoo Kim; Alice Hahn
TAGS: alzheimer's disease, amyloid, brain, eye, mice, microscopy, fluorescence, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):34. https://doi.org/10.1167/iovs.66.3.34

Includes: Multimedia, Supplemental Content

Retina March 2025

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

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Ivana Mihalek; Hanna De Bruyn; Tomislav Glavan; Annie M. Lancos; Caitlin M. Ciolfi; Katarzyna Malendowicz; Sigrid Aslaksen; Laurie L. Molday; Robert S. Molday; Anne B. Fulton
TAGS: abca4 gene, fovea centralis, fundus autofluorescence imaging, pixel, stargardt's disease, artifacts, eye
Trans. Vis. Sci. Tech.. 2025; 14(3):16. https://doi.org/10.1167/tvst.14.3.16

Includes: Supplemental Content

Retina March 2025

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

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Zhifan Chen; Shuoxin Liao; Guangzhong Chen; Changmao Li; Chunling Liu; Junbin Liu; Guangyu Wu; Zheng Lyu; Mengya Liu; Xiyu Wu; Guixian Ma; Qianli Meng
TAGS: carotid stenosis, ischemic stroke
Trans. Vis. Sci. Tech.. 2025; 14(3):14. https://doi.org/10.1167/tvst.14.3.14

Includes: Supplemental Content

Artificial Intelligence March 2025

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

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Pétra Eid; Abderrahmane Bourredjem; Atif Anwer; Catherine Creuzot-Garcher; Pearse Andrew Keane; Yukun Zhou; Siegfried Wagner; Fabrice Meriaudeau; Louis Arnould
TAGS: biological markers, datasets, fundus photography, retinal imaging, software
Trans. Vis. Sci. Tech.. 2025; 14(3):13. https://doi.org/10.1167/tvst.14.3.13

Includes: Supplemental Content

Retina March 2025

Artificial Intelligence Versus Rules-Based Approach for Segmenting NonPerfusion Area in a DRCR Retina Network Optical Coherence Tomography Angiography Dataset

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Tristan T. Hormel; Wesley T. Beaulieu; Jie Wang; Jennifer K. Sun; Yali Jia
TAGS: nasopharyngeal aspirate, retina, angiogram, optical coherence tomography, datasets, artificial intelligence
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):22. https://doi.org/10.1167/iovs.66.3.22

Includes: Supplemental Content

Review March 2025

Advances in OCT Angiography

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Tristan T. Hormel; David Huang; Yali Jia
TAGS: angiogram, artifacts, diagnostic imaging, deep learning, fluid flow, body tissue
Trans. Vis. Sci. Tech.. 2025; 14(3):6. https://doi.org/10.1167/tvst.14.3.6

Retina March 2025

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

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Danyang Yu; Di Wu; Haoru Li; Hua Rong; Qing He; Xia Zhang; He Xu; Mengdi Chai; Yifan Zhou; Ruihua Wei
TAGS: 3d mri, myopic foveoschisis, sclera, surgical procedures, operative, preoperative care, postoperative care, retinoschisis
Trans. Vis. Sci. Tech.. 2025; 14(3):5. https://doi.org/10.1167/tvst.14.3.5

Artificial Intelligence March 2025

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

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Bo Zheng; Chen Wang; Maotao Zhang; Shaojun Zhu; Maonian Wu; Tao Wu; Weihua Yang; Lu Chen
TAGS: learning, macular disorders, fundus photography, color, datasets
Trans. Vis. Sci. Tech.. 2025; 14(3):4. https://doi.org/10.1167/tvst.14.3.4

Includes: Supplemental Content

Article March 2025

The Boynton Illusion: Chromatic edge attraction to a luminance contour

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Jingyi He; Yesenia Taveras-Cruz; Rhea T. Eskew, Jr.
TAGS: color, illusions, judgment, luminance, retinal cone, perception
Journal of Vision. 2025; 25(3):3. https://doi.org/10.1167/jov.25.3.3

Retina March 2025

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

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Anupam K. Garg; Jingyu Wang; Bailee Alonzo; Ji Yi; Amir H. Kashani
TAGS: hydroxychloroquine, optical coherence tomography, photoreceptors, vaccine information sheets, visible light, diagnostic imaging, toxic effect
Trans. Vis. Sci. Tech.. 2025; 14(3):2. https://doi.org/10.1167/tvst.14.3.2

Includes: Supplemental Content

Retina February 2025

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

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Hiroyuki Takahashi; Yunchan Hwang; Jungeun Won; Muhammad Usman Jamil; Antonio Yaghy; Michelle C. Liang; Caroline R. Baumal; Andre J. Witkin; Kyoko Ohno-Matsui; Jay S. Duker; James G. Fujimoto; Nadia K. Waheed
TAGS: diabetic retinal microaneurysm, diabetic retinopathy, fluid flow, macrophage activation syndrome, meconium aspiration syndrome, retinal microaneurysm, vascular flow, blood capillaries
Trans. Vis. Sci. Tech.. 2025; 14(2):27. https://doi.org/10.1167/tvst.14.2.27

Article February 2025

Temporal dynamics of human color processing measured using a continuous tracking task

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Michael A. Barnett; Benjamin M. Chin; Geoffrey K. Aguirre; Johannes Burge; David H. Brainard
TAGS: color, retinal cone
Journal of Vision. 2025; 25(2):12. https://doi.org/10.1167/jov.25.2.12

Includes: Supplemental Content

Visual Neuroscience February 2025

Retinal Responses to Short- and Longer-Term Predominant ON or OFF Stimulation in Emmetropes and Myopes

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Sandra Wagner; Annemarie Settele; Torsten Strasser
TAGS: electroretinography, eye, myopia, reading (activity), refractive errors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):66. https://doi.org/10.1167/iovs.66.2.66

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging February 2025

Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning–Based baPWV Index From Color Fundus Photographs

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Michiyuki Saito; Mizuho Mitamura; Kanae Fukutsu; Dong Zhenyu; Ryo Ando; Satoru Kase; Satoshi Katsuta; Susumu Ishida
TAGS: attention, color, deep learning, fundus photography, training
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):63. https://doi.org/10.1167/iovs.66.2.63

Includes: Supplemental Content

Visual Neuroscience February 2025

Temporal Transformation of the Rod Single-Photon Response in the Retinal Circuitry

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Haruhisa Okawa; Alapakkam P. Sampath
TAGS: ganglia, photons, rod photoreceptors, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):52. https://doi.org/10.1167/iovs.66.2.52

Retina February 2025

Accessible LED Lightbox for Light-induced Retinal Damage in Pigmented Mice

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Hunter L. Aliff; Alexis B. Crockett; Micah A. Chrenek; John M. Nickerson; Jeffrey H. Boatright; Oxana Tseytlin; Matthew Johnson; Hayley G. Bockius; Sierra G. Kuzak; Visvanathan Ramamurthy
TAGS: mice, mice, inbred c57bl, erg protein, human, electroretinography, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):49. https://doi.org/10.1167/iovs.66.2.49

Includes: Supplemental Content

Glaucoma February 2025

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

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Raymond Fang; Pengpeng Zhang; Daniel Kim; Junghun Kweon; Cheng Sun; Alex S. Huang; Hao F. Zhang
TAGS: optical coherence tomography, pilocarpine, schlemm's canal, visible light, eye, diagnostic imaging, vaccine information sheets, language morphology, morphology
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):47. https://doi.org/10.1167/iovs.66.2.47

Multidisciplinary Ophthalmic Imaging February 2025

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

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Ye He; Pearl Heumann; Melissa Weilin Song; Shin Kadomoto; Srinivas R. Sadda; Ilina D. Pluym; Irena Tsui
TAGS: angiogram, optical coherence tomography, placental insufficiency, pregnancy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):36. https://doi.org/10.1167/iovs.66.2.36

Retina February 2025

Preconception Paternal Alcohol Consumption Elicits Postnatal Changes in Neural Retinas of the Offspring

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Kofi Owusu-Ansah; Kara N. Thomas; Kelsey Cox; Dylan L. Pham; Wei-Lin Chen; Michael Lee Ko; Michael C. Golding; Gladys Yi-Ping Ko
TAGS: alcohol drinking, ethanol, neural retina, offspring, retina, mice, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):16. https://doi.org/10.1167/iovs.66.2.16

Retina February 2025

Structure–Function Relationships in Geographic Atrophy Based on Mesopic Microperimetry, Fundus Autofluorescence, and Optical Coherence Tomography

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Souvick Mukherjee; Thilaka Arunachalam; Cameron Duic; Maria Abraham; Christine Orndahl; Supriya Menezes; Elvira Agrón; Maximilian Pfau; Tharindu de Silva; Clare Bailey; Alisa T. Thavikulwat; Sunil Bellur; SriniVas R. Sadda; Emily Y. Chew; Brett G. Jeffrey; Wai T. Wong; Tiarnan D. L. Keenan
TAGS: age-related macular degeneration, nonexudative, fundus autofluorescence imaging, optical coherence tomography, scotoma, vision, retina
Trans. Vis. Sci. Tech.. 2025; 14(2):7. https://doi.org/10.1167/tvst.14.2.7

Includes: Supplemental Content

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Three-Dimensional β-Amyloid Burden Correlation Between the Eye and Brain in Alzheimer's Disease Mice Using Light-Sheet Fluorescence Microscopy

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

Artificial Intelligence Versus Rules-Based Approach for Segmenting NonPerfusion Area in a DRCR Retina Network Optical Coherence Tomography Angiography Dataset

Advances in OCT Angiography

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

The Boynton Illusion: Chromatic edge attraction to a luminance contour

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

Temporal dynamics of human color processing measured using a continuous tracking task

Retinal Responses to Short- and Longer-Term Predominant ON or OFF Stimulation in Emmetropes and Myopes

Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning–Based baPWV Index From Color Fundus Photographs

Temporal Transformation of the Rod Single-Photon Response in the Retinal Circuitry

Accessible LED Lightbox for Light-induced Retinal Damage in Pigmented Mice

Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemm's Canal Anatomy and Segmental Pilocarpine Response

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

Preconception Paternal Alcohol Consumption Elicits Postnatal Changes in Neural Retinas of the Offspring

Structure–Function Relationships in Geographic Atrophy Based on Mesopic Microperimetry, Fundus Autofluorescence, and Optical Coherence Tomography

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