Immunology and Microbiology

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Biochemistry and Molecular Biology October 2019

Therapeutic Effect of Curcumin, a Plant Polyphenol Extracted From Curcuma longae , in Fibroblasts From Patients With Graves' Orbitopathy

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Jihei Sara Lee; Jinjoo Kim; Eun Jig Lee; Jin Sook Yoon
TAGS: curcumin, fibroblasts, polyphenols, plants
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4129-4140. doi: 10.1167/iovs.19-27376

Immunology and Microbiology September 2019

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

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Steffani Fitzpatrick; Robert Lausch; Robert A. Barrington
TAGS: cornea, human herpesvirus 1, infection, t-lymphocytes, mice, interleukin-17
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3952-3962. doi: 10.1167/iovs.19-27810

Cornea September 2019

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

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Ziye Rong; Jiaxin Hu; David R. Corey; V. Vinod Mootha
TAGS: proteins, rna, cornea, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3980-3991. doi: 10.1167/iovs.19-27641

Includes: Supplemental Content

Genetics September 2019

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

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Ebony Liu; Georgia Kaidonis; Bennet J. McComish; Mark C. Gillies; Sotoodeh Abhary; Rohan W. Essex; John H. Chang; Bishwanath Pal; Mark Daniell; Stewart Lake; Nikolai Petrovsky; Alex W. Hewitt; Alicia Jenkins; Ecosse L. Lamoureux; Jonathan M. Gleadle; Jamie E. Craig; Kathryn P. Burdon
TAGS: diabetes mellitus, type 1, diabetic retinopathy, genes, genetics, micrornas, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3937-3942. doi: 10.1167/iovs.18-25570

Includes: Supplemental Content

Lens September 2019

Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention

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Andrew J. O. Smith; Julie A. Eldred; I. Michael Wormstone
TAGS: lens, crystalline, resveratrol, wound healing, lens (device), after-cataract, prevention, fibrosis, epithelial to mesenchymal transition
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3863-3877. doi: 10.1167/iovs.18-26248

Articles September 2019

Comparative Study of Chemical Composition, Molecular and Rheological Properties of Silicone Oil Medical Devices

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Raniero Mendichi; Alberto Giacometti Schieroni; Daniele Piovani; Davide Allegrini; Mariantonia Ferrara; Mario R. Romano
TAGS: biocompatibility, comparative study research, devices, medical, molecular mass, silicone oils, spectrum analysis, viscosity, polymers
Trans. Vis. Sci. Tech.. 2019; 8(5):9. doi: 10.1167/tvst.8.5.9

Articles September 2019

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

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Kathryn L. Pepple; Leslie Wilson; Russell N. Van Gelder; Marina Kovaleva; Obinna C. Ubah; John Steven; Caroline J. Barelle; Andrew Porter
TAGS: cytokine, inflammation, ligands, receptors, antigen, sharks, t-lymphocytes, tumor necrosis factor-alpha, uveitis, dexamethasone, eye
Trans. Vis. Sci. Tech.. 2019; 8(5):11. doi: 10.1167/tvst.8.5.11

Includes: Supplemental Content

Cornea September 2019

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

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Hyun Jung Lee; Soojung Shin; Seul-Gi Yoon; Eun Jeong Cheon; So-Hyang Chung
TAGS: animal model, chloroquine, dry eye syndromes, mice, sjogren's syndrome, syndrome, autophagy, sjogren's syndrome a antibody, phenotype, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3708-3716. doi: 10.1167/iovs.19-27469

Includes: Supplemental Content

Immunology and Microbiology September 2019

S-layer Impacts the Virulence of Bacillus in Endophthalmitis

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Md Huzzatul Mursalin; Phillip S. Coburn; Erin Livingston; Frederick C. Miller; Roger Astley; Agnès Fouet; Michelle C. Callegan
TAGS: bacillus, endophthalmitis, proteins, s-layer, speech-language pathology assistants, eye, virulence, mice, speech-language pathologists
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3727-3739. doi: 10.1167/iovs.19-27453

Articles August 2019

Conjunctival HLA-DR Expression and Its Association With Symptoms and Signs in the DREAM Study

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Neeta S. Roy; Yi Wei; Yinxi Yu; Gui-Shuang Ying; Eric Kuklinski; Brendan Barry; Maureen G. Maguire; Reza Dana; Mary Brightwell-Arnold; Penny A. Asbell; for the Dry Eye Assessment and Management (DREAM) Study Group
TAGS: conjunctiva, dreams, hla-dr antigens, human leukocyte antigens, signs and symptoms, electroconvulsive therapy, epidural cortical stimulation, mandibulofacial dysostosis
Trans. Vis. Sci. Tech.. 2019; 8(4):31. doi: 10.1167/tvst.8.4.31

Glaucoma August 2019

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

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Vidhya R. Rao; Jonathan D. Lautz; Simon Kaja; Eileen M. Foecking; Emőke Lukács; Evan B. Stubbs, Jr
TAGS: antioxidants, attenuation, mitochondria, signal transduction, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3613-3624. doi: 10.1167/iovs.19-27542

Cornea August 2019

Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population

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Nihal Kaplan; Junyi Wang; Brian Wray; Priyam Patel; Wending Yang; Han Peng; Robert M. Lavker
TAGS: cornea, epithelium, mice, rna, small cytoplasmic, autophagy, genes, rna, beclin-1
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3570-3583. doi: 10.1167/iovs.19-27656

Includes: Supplemental Content

Retinal Cell Biology August 2019

COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

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Keith D. Rochfort; Lara S. Carroll; Peter Barabas; Timothy M. Curtis; Balamurali K. Ambati; Niall Barron; Philip M. Cummins
TAGS: angiotensin i, hyperglycemia, hyperglycemic agents, endothelial cells, blood-retinal barrier, phenotype
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3547-3555. doi: 10.1167/iovs.19-27644

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2019

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

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Gloriane Schnabolk; Bärbel Rohrer; Kit N. Simpson
TAGS: age-related macular degeneration, nonexudative, medicare, rheumatoid arthritis, survival analysis, cohort studies, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3520-3526. doi: 10.1167/iovs.18-26444

Includes: Supplemental Content

Retinal Cell Biology August 2019

Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

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Qitao Zhang; Feriel Presswalla; Melissa Calton; Carol Charniga; Jeffrey Stern; Sally Temple; Douglas Vollrath; David N. Zacks; Robin R. Ali; Debra A. Thompson; Jason M. L. Miller
TAGS: fetus, lipofuscin, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3468-3479. doi: 10.1167/iovs.19-26690

Includes: Supplemental Content

Anatomy and Pathology/Oncology August 2019

Evaluation of Lens Capsule Stability Using Capsular Tension Ring, Iris Retractor, and Capsule Expander Using a Porcine Model With Zonular Dehiscence

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Saori Yaguchi; Shigeo Yaguchi; Hiroko Bissen-Miyajima
TAGS: dehiscence, immune reconstitution inflammatory syndrome, lens capsule, crystalline, lens, crystalline, retractor, suidae, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3507-3513. doi: 10.1167/iovs.19-27449

Editorial August 2019

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2019; 8(4):r. doi: 10.1167/tvst.8.4.r

Editorial August 2019

Reviewers

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TAGS: christianity, reading (activity), cataract-alopecia-sclerodactyly syndrome, congenital absence of limb, fexofenadine, hematoma of pinna, immune reconstitution inflammatory syndrome, microangiopathic hemolytic anemia, silver, vacterl association with hydrocephalus
Journal of Vision. 2019; 19(9):r. doi: 10.1167/19.9.r

Editorial August 2019

Reviewers

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TAGS: acoustic evoked brain stem potentials, arthritis, juvenile rheumatoid, aves, betula, burns, chewing, christianity, cluster headache, enzyme-linked immunosorbent assay, esters
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3414-3420. doi: 10.1167/iovs.19-28020

Immunology and Microbiology August 2019

Loss of ICP22 in HSV-1 Elicits Immune Infiltration and Maintains Stromal Keratitis Despite Reduced Primary and Latent Virus Infectivity

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Harry H. Matundan; Ujjaldeep Jaggi; Shaohui Wang; Homayon Ghiasi
TAGS: eye, human herpesvirus 1, mice, viruses, keratitis, stromal, pathogenicity, cornea, cd80 antigens, infection
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3398-3406. doi: 10.1167/iovs.19-27701

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Therapeutic Effect of Curcumin, a Plant Polyphenol Extracted From Curcuma longae , in Fibroblasts From Patients With Graves' Orbitopathy

CCR6-Positive γδ T Cells Provide Protection Against Intracorneal HSV-1 Infection

Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy

MicroRNA-Related Genetic Variants Are Associated With Diabetic Retinopathy in Type 1 Diabetes Mellitus

Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention

Comparative Study of Chemical Composition, Molecular and Rheological Properties of Silicone Oil Medical Devices

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model

S-layer Impacts the Virulence of Bacillus in Endophthalmitis

Conjunctival HLA-DR Expression and Its Association With Symptoms and Signs in the DREAM Study

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population

COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

Increased Nonexudative Age-Related Macular Degeneration Diagnosis Among Medicare Beneficiaries With Rheumatoid Arthritis

Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

Evaluation of Lens Capsule Stability Using Capsular Tension Ring, Iris Retractor, and Capsule Expander Using a Porcine Model With Zonular Dehiscence

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

Reviewers

Reviewers

Loss of ICP22 in HSV-1 Elicits Immune Infiltration and Maintains Stromal Keratitis Despite Reduced Primary and Latent Virus Infectivity

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Immunology and Microbiology

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