Immunology and Microbiology

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Immunology and Microbiology July 2019

Glycyrrhizin Use for Multi-Drug Resistant Pseudomonas aeruginosa : In Vitro and In Vivo Studies

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Linda D. Hazlett; Sandamali A. Ekanayaka; Sharon A. McClellan; Rebecca Francis
TAGS: ciprofloxacin, glycyrrhizic acid, keratitis, pseudomonas aeruginosa
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2978-2989. doi: 10.1167/iovs.19-27200

Cornea July 2019

Differentiation Capacity of Human Mesenchymal Stem Cells into Keratocyte Lineage

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Aurelie Dos Santos; Alis Balayan; Martha L. Funderburgh; John Ngo; James L. Funderburgh; Sophie X. Deng
TAGS: keratocytes, stem cell, mesenchymal, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3013-3023. doi: 10.1167/iovs.19-27008

Includes: Supplemental Content

Anatomy and Pathology/Oncology July 2019

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

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Jolique A. van Ipenburg; Nadine E. de Waard; Nicole C. Naus; Martine J. Jager; Dion Paridaens; Robert M. Verdijk
TAGS: atypical, chemokine receptors, chemokines, conjunctiva, cxcr4 receptors, melanoma, nevus, neoplasm metastasis, immune reconstitution inflammatory syndrome, insulin receptor substrate proteins, malignant melanoma of conjunctiva, cell lines, internal revenue service
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2950-2957. doi: 10.1167/iovs.19-27162

Cornea July 2019

Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye

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Bowen Wang; Lulu Peng; Hong Ouyang; Li Wang; Dalian He; Jing Zhong; Yichen Xiao; Yuqing Deng; Meng Li; Saiqun Li; Jin Yuan
TAGS: autophagy, dry eye syndromes, oxidative stress, western blotting, stress, mice, cell survival
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2836-2847. doi: 10.1167/iovs.19-27072

Includes: Supplemental Content

Biochemistry and Molecular Biology July 2019

Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells

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Feng He; Ralph M. Nichols; Lavanya Kailasam; Theodore G. Wensel; Melina A. Agosto
TAGS: biopharmaceutics classification system, phosphatidylinositols, phosphotransferases, retinal bipolar cells, tissue degeneration, mice, tissue membrane, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2861-2874. doi: 10.1167/iovs.19-26586

Includes: Supplemental Content

Articles June 2019

Controlled Release of Vancomycin From a Thermoresponsive Hydrogel System for the Prophylactic Treatment of Postoperative Acute Endophthalmitis

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Emily Dosmar; Wenqiang Liu; Geeya Patel; Alison Rogozinski; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: endophthalmitis, hydrogel, vancomycin, infection, postoperative care, prevention, injections, saline solutions
Trans. Vis. Sci. Tech.. 2019; 8(3):53. doi: 10.1167/tvst.8.3.53

Glaucoma June 2019

Rosiglitazone Treatment Prevents Postoperative Fibrosis in a Rabbit Model of Glaucoma Filtration Surgery

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Feng Zhang; Ke Liu; Mengdan Cao; Jing Qu; Dengming Zhou; Zheng Pan; Xuanchu Duan; Yong Zhou
TAGS: autophagy, blister, fibrosis, filtering surgery, glaucoma, oryctolagus cuniculus, postoperative care, rosiglitazone, intraocular pressure, genes, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2743-2752. doi: 10.1167/iovs.18-26526

Biochemistry and Molecular Biology June 2019

Modulation of cPKCγ on Synapsin-Ia/b–Specific Phosphorylation Sites in the Developing Visual Cortex of Mice

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Tao Fu; Jing Wang; Yichao Ding; Yunxia Zhang; Song Han; Junfa Li
TAGS: mice, synapsins, visual cortex, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2676-2684. doi: 10.1167/iovs.19-26675

Retina June 2019

Polypoidal Choroidal Vasculopathy Associate With Diminished Regulatory T Cells That Are Polarized Into a T Helper 2-Like Phenotype

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Yousif Subhi; Marie Krogh Nielsen; Christopher Rue Molbech; Akio Oishi; Amardeep Singh; Mogens Holst Nissen; Torben Lykke Sørensen
TAGS: cytokine, exudative age-related macular degeneration, helper-inducer t-lymphocytes, interleukin-33, phenotype, plasma, polypoidal choroidal vasculopathy, regulatory t-lymphocytes, flow cytometry, immunology, interleukin-4
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2583-2590. doi: 10.1167/iovs.19-26882

Includes: Supplemental Content

Cornea June 2019

Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye

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Pooja Khamar; Archana Padmanabhan Nair; Rohit Shetty; Tanuja Vaidya; Murali Subramani; Murugeswari Ponnalagu; Kamesh Dhamodaran; Sharon D'souza; Anuprita Ghosh; Natasha Pahuja; Rashmi Deshmukh; Prerna Ahuja; Kanchan Sainani; Rudy M. M. A. Nuijts; Debashish Das; Arkasubhra Ghosh; Swaminathan Sethu
TAGS: cornea, dendritic cells, dry eye syndromes, pain perception, signs and symptoms, vitamin d
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2532-2542. doi: 10.1167/iovs.19-26914

Includes: Supplemental Content

Articles June 2019

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

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Anup Kumar Ghosh; Shivaprakash Mandya Rudramurthy; Amit Gupta; Hansraj Choudhary; Shreya Singh; Anchal Thakur; Manu Jatana
TAGS: amphotericin b, antifungal agents, cornea, did not receive therapy or drug, fungal keratitis, liposomes, oryctolagus cuniculus, keratitis
Trans. Vis. Sci. Tech.. 2019; 8(3):35. doi: 10.1167/tvst.8.3.35

Immunology and Microbiology June 2019

Predictive Factors of Intraocular Pressure Level Evolution Over Time and Glaucoma Severity in Fuchs' Heterochromic Iridocyclitis

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Sara Touhami; Antoine Vanier; Alessandra Rosati; Magdalena Bojanova; Bouchra Benromdhane; Phuc Lehoang; Flore Rozenberg; Bahram Bodaghi
TAGS: glaucoma, ocular hypertension, antibodies, intraocular pressure, fuchs' heterochromic cyclitis, predictor variable, glaucoma surgery
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2399-2405. doi: 10.1167/iovs.18-24597

Immunology and Microbiology May 2019

PD-L1/PD1 Expression, Composition of Tumor-Associated Immune Infiltrate, and HPV Status in Conjunctival Squamous Cell Carcinoma

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Priyadharsini Nagarajan; Christian El-Hadad; Stephen K. Gruschkus; Jing Ning; Courtney W. Hudgens; Oded Sagiv; Neil Gross; Michael T. Tetzlaff; Bita Esmaeli
TAGS: squamous cell carcinoma, human papillomavirus, conjunctiva, neoplasms, tumor cells, infiltrates, programmed cell death 1 ligand 1
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2388-2398. doi: 10.1167/iovs.19-26894

Includes: Supplemental Content

Cornea May 2019

MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells

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Kyu-Yeon Han; Jin-Hong Chang; Dimitri T. Azar
TAGS: endothelial cells, proteins, exosomes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2321-2329. doi: 10.1167/iovs.18-26277

Immunology and Microbiology May 2019

TRPM1 Autoantibodies in Melanoma Patients Without Self-Reported Visual Symptoms

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Robert M. Duvoisin; Gaoying Ren; Tammie L. Haley; Matthew H. Taylor; Catherine W. Morgans
TAGS: autoantibodies, melanoma, malignant melanoma, cutaneous, visual symptoms, self-report
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2330-2335. doi: 10.1167/iovs.19-26775

Cornea May 2019

Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome

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Mathias Kaurstad Morthen; Sara Tellefsen; Stephen M. Richards; Scott M. Lieberman; Raheleh Rahimi Darabad; Wendy R. Kam; David A. Sullivan
TAGS: androgens, testosterone, gene expression, autoimmunity, genes, mice, inbred nod, sjogren's syndrome, body tissue, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2181-2197. doi: 10.1167/iovs.19-26815

Retina May 2019

Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS

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Douglas A. Jabs; Mark L. Van Natta; Garrett Trang; Norman Jones; Jeffrey M. Milush; Ryan Cheu; Nichole R. Klatt; Jeong Won Pak; Ronald P. Danis; Peter W. Hunt
TAGS: acquired immunodeficiency syndrome, inflammation, linear regression, retinal vascular caliber
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2218-2225. doi: 10.1167/iovs.18-26070

Includes: Supplemental Content

Retina May 2019

Intravitreal Fluocinolone Acetonide May Decelerate Diabetic Retinal Neurodegeneration

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Stephanie K. Lynch; Kyungmoo Lee; Zhi Chen; James C. Folk; Ursula Schmidt-Erfurth; Bianca S. Gerendas; Andreas Wahle; Charles C. Wykoff; Michael D. Abràmoff
TAGS: diabetes mellitus, fluocinolone acetonide, nerve degeneration, left ventricular area fractional change, cyclophosphamide/doxorubicin/fluorouracil protocol, right ventricular fractional area change
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2134-2139. doi: 10.1167/iovs.18-24643

Anatomy and Pathology/Oncology May 2019

A Murine Model of Acute Allergic Conjunctivitis Induced by Continuous Exposure to Particulate Matter 2.5

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Yu-Jun Tang; Han-Hsin Chang; Chun-Yi Chiang; Chane-Yu Lai; Min-Yen Hsu; King-Rong Wang; Hsin-Hsuan Han; Ling-Yun Chen; David Pei-Cheng Lin
TAGS: allergic conjunctivitis, eyelid, goblet cells, metals, heavy, signs and symptoms, conjunctiva, eye, mice, lichtenberg figures, cervical mucous arborization, volume, eyelid edema, particulate matter, scratching
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2118-2126. doi: 10.1167/iovs.18-26214

Glaucoma May 2019

Effects of Salidroside on Trabecular Meshwork Cell Extracellular Matrix Expression and Mouse Intraocular Pressure

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Yuchen Fan; Li Guo; Jiahong Wei; Junzhao Chen; Hao Sun; Tao Guo
TAGS: extracellular matrix, ocular hypertension, body tissue, trabecular meshwork, intraocular pressure, mice, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2072-2082. doi: 10.1167/iovs.19-26585

Includes: Supplemental Content

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Glycyrrhizin Use for Multi-Drug Resistant Pseudomonas aeruginosa : In Vitro and In Vivo Studies

Differentiation Capacity of Human Mesenchymal Stem Cells into Keratocyte Lineage

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye

Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells

Controlled Release of Vancomycin From a Thermoresponsive Hydrogel System for the Prophylactic Treatment of Postoperative Acute Endophthalmitis

Rosiglitazone Treatment Prevents Postoperative Fibrosis in a Rabbit Model of Glaucoma Filtration Surgery

Modulation of cPKCγ on Synapsin-Ia/b–Specific Phosphorylation Sites in the Developing Visual Cortex of Mice

Polypoidal Choroidal Vasculopathy Associate With Diminished Regulatory T Cells That Are Polarized Into a T Helper 2-Like Phenotype

Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

Predictive Factors of Intraocular Pressure Level Evolution Over Time and Glaucoma Severity in Fuchs' Heterochromic Iridocyclitis

PD-L1/PD1 Expression, Composition of Tumor-Associated Immune Infiltrate, and HPV Status in Conjunctival Squamous Cell Carcinoma

MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells

TRPM1 Autoantibodies in Melanoma Patients Without Self-Reported Visual Symptoms

Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome

Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS

Intravitreal Fluocinolone Acetonide May Decelerate Diabetic Retinal Neurodegeneration

A Murine Model of Acute Allergic Conjunctivitis Induced by Continuous Exposure to Particulate Matter 2.5

Effects of Salidroside on Trabecular Meshwork Cell Extracellular Matrix Expression and Mouse Intraocular Pressure

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