Immunology and Microbiology

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Article November 2018

Visual perceptual learning modulates decision network in the human brain: The evidence from psychophysics, modeling, and functional magnetic resonance imaging

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Ke Jia; Xin Xue; Jong-Hwan Lee; Fang Fang; Jiaxiang Zhang; Sheng Li
TAGS: arthritis, juvenile rheumatoid, learning, motion, psychophysics, brain, functional magnetic resonance imaging, training, perceptual learning
Journal of Vision. 2018; 18(12):9. doi: 10.1167/18.12.9

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

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Yong Lin; Li Li; Junjie Liu; Xiaoting Zhao; Juxiu Ye; Peter S. Reinach; Jia Qu; Dongsheng Yan
TAGS: angiogenesis, vascular endothelial growth factor a, western blotting, endothelial cells, vascular endothelial growth factor receptor-2, down-regulation, mice, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5431-5440. doi: 10.1167/iovs.17-23558

Includes: Supplemental Content

Retina November 2018

Time-Course Change in Eye Shape and Development of Staphyloma in Highly Myopic Eyes

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Tomotaka Wakazono; Kenji Yamashiro; Masahiro Miyake; Masayuki Hata; Manabu Miyata; Akihito Uji; Hideo Nakanishi; Akio Oishi; Hiroshi Tamura; Sotaro Ooto; Akitaka Tsujikawa
TAGS: myopia, time factors, eye, heterogeneity of variance, shape, staphyloma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5455-5461. doi: 10.1167/iovs.18-24754

Letters to the Editor November 2018

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Edoardo Midena; Elisabetta Pilotto; Silvia Bini
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5366-5366. doi: 10.1167/iovs.18-25611

Letters to the Editor November 2018

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Hyungwoo Lee; Hyewon Chung
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5367-5367. doi: 10.1167/iovs.18-25825

Retina November 2018

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

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Shueh Wen Lim; Esther Bandala-Sanchez; Maria Kolic; Sophie L. Rogers; Annie K. McAuley; Lyndell L. Lim; Sanjeewa S. Wickremasinghe
TAGS: cytokine, vascular endothelial growth factor a, inflammation, eye, macular edema, diabetic, ranibizumab
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5382-5390. doi: 10.1167/iovs.17-23325

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

CD40 Enhances Sphingolipids in Orbital Fibroblasts: Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' Orbitopathy

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Svenja Plöhn; Bärbel Edelmann; Lukasz Japtok; Xingxuan He; Matthias Hose; Wiebke Hansen; Edward H. Schuchman; Anja Eckstein; Utta Berchner-Pfannschmidt
TAGS: fibroblasts, cd40 antigens, cd40 ligand, sphingolipids, t-lymphocyte, sphingosine-1-phosphate phosphatase
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5391-5397. doi: 10.1167/iovs.18-25466

Includes: Supplemental Content

Articles October 2018

Matrix Metalloproteinase 9 Point-of-Care Immunoassay Result Predicts Response to Topical Cyclosporine Treatment in Dry Eye Disease

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Jae Yong Park; Bum Gi Kim; Jae Suk Kim; Je Hyung Hwang
TAGS: dry eye syndromes, gelatinase b, immunoassay, cyclosporine
Trans. Vis. Sci. Tech.. 2018; 7(5):31. doi: 10.1167/tvst.7.5.31

Cornea October 2018

Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing

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Ravand Samaeekia; Behnam Rabiee; Ilham Putra; Xiang Shen; Young Jae Park; Peiman Hematti; Medi Eslani; Ali R. Djalilian
TAGS: epithelium, wound healing, cornea, exosomes
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5194-5200. doi: 10.1167/iovs.18-24803

Retinal Cell Biology October 2018

Failure of Autophagy–Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6 nclf Mice

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Philipp von Eisenhart-Rothe; Alexandra Grubman; Ursula Greferath; Linda J. Fothergill; Andrew I. Jobling; Joanna A. Phipps; Anthony R. White; Erica L. Fletcher; Kirstan A. Vessey
TAGS: autophagy, photoreceptors, retinal degeneration, rod photoreceptors, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5082-5097. doi: 10.1167/iovs.18-24757

Glaucoma October 2018

Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure

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Junkai Tan; Ning Fan; Ningli Wang; BingKai Feng; Ming Yang; Guo Liu; Yun Wang; Xianjun Zhu; Paul L. Kaufman; Iok-Hou Pang; Xuyang Liu
TAGS: actins, injections, lentivirus, trabecular meshwork, eye, intraocular pressure, rats, lentiviral vector
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4937-4944. doi: 10.1167/iovs.18-24978

Articles October 2018

Development and Validation of the Singapore Thyroid Eye Disease Quality of Life Questionnaire

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Melissa H. Y. Wong; Eva Fenwick; Ai Tee Aw; Ecosse L. Lamoureux; Lay Leng Seah
TAGS: graves' ophthalmopathy, psychometrics, questionnaires, singapore, quality of life
Trans. Vis. Sci. Tech.. 2018; 7(5):14. doi: 10.1167/tvst.7.5.14

Includes: Supplemental Content

Immunology and Microbiology September 2018

Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation

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Sudha Neelam; Jessamee Mellon; Amber Wilkerson; Jerry Y. Niederkorn
TAGS: adoptive transfer, immunization, injections, ovum, patient isolation, cornea, eye, mice, spleen, nerve ablation, immune privilege
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4738-4747. doi: 10.1167/iovs.18-24894

Immunology and Microbiology September 2018

Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease

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Shenglan Yi; Rui Chang; Jianping Hu; Yiguo Qiu; Qingfeng Wang; Qingfeng Cao; Gangxiang Yuan; Guannan Su; Chunjiang Zhou; Yao Wang; Aize Kijlstra; Peizeng Yang
TAGS: tumor necrosis factors, dendritic cells, disabled persons, monocytes, uveomeningoencephalitic syndrome, interleukin-6, proteins, protein overexpression
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4662-4669. doi: 10.1167/iovs.18-24630

Includes: Supplemental Content

Immunology and Microbiology September 2018

In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

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Gabrielle Gomart; Julie Denis; Tristan Bourcier; Anne Dory; Ahmed Abou-Bacar; Ermanno Candolfi; Arnaud Sauer
TAGS: acanthamoeba, cysts, ultraviolet a radiation, titanium dioxide, trophozoite
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4567-4571. doi: 10.1167/iovs.18-25003

Includes: Supplemental Content

Article September 2018

Experience-dependent long-term facilitation of skew adaptation

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Selam W. Habtegiorgis; Katharina Rifai; Markus Lappe; Siegfried Wahl
TAGS: facilitation, perceptual aftereffect
Journal of Vision. 2018; 18(9):7. doi: 10.1167/18.9.7

Includes: Supplemental Content

Retinal Cell Biology September 2018

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

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Nilisha Fernando; Yvette Wooff; Riemke Aggio-Bruce; Joshua A. Chu-Tan; Haihan Jiao; Catherine Dietrich; Matt Rutar; Melissa Rooke; Deepthi Menon; Janis T. Eells; Krisztina Valter; Philip G. Board; Jan Provis; Riccardo Natoli
TAGS: oxidative stress, photoreceptors, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4362-4374. doi: 10.1167/iovs.18-24627

Immunology and Microbiology August 2018

Identification and Visualization of a Distinct Microbiome in Ocular Surface Conjunctival Tissue

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Jerome Ozkan; Minas Coroneo; Mark Willcox; Bernd Wemheuer; Torsten Thomas
TAGS: fornix (brain), body tissue, conjunctiva, microorganisms, community, microbiome
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4268-4276. doi: 10.1167/iovs.18-24651

Includes: Supplemental Content

Cornea August 2018

TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway

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Xinhan Cui; Nan Gao; Rao Me; Jianjiang Xu; Fu-Shin X. Yu
TAGS: dendritic cells, keratitis, infection, cornea, mice, bacterial keratitis, thymic stromal lymphopoietin, pseudomonas aeruginosa infection
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4228-4237. doi: 10.1167/iovs.18-24672

Includes: Supplemental Content

Immunology and Microbiology August 2018

Detection of Complement Activators in Immune Attack Eyes After iPS-Derived Retinal Pigment Epithelial Cell Transplantation

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Sunao Sugita; Kenichi Makabe; Shota Fujii; Masayo Takahashi
TAGS: complement system proteins, eye, transplantation, transcriptional activation, idiopathic pneumonia syndrome, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4198-4209. doi: 10.1167/iovs.18-24769

Includes: Supplemental Content

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Visual perceptual learning modulates decision network in the human brain: The evidence from psychophysics, modeling, and functional magnetic resonance imaging

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

Time-Course Change in Eye Shape and Development of Staphyloma in Highly Myopic Eyes

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

CD40 Enhances Sphingolipids in Orbital Fibroblasts: Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' Orbitopathy

Matrix Metalloproteinase 9 Point-of-Care Immunoassay Result Predicts Response to Topical Cyclosporine Treatment in Dry Eye Disease

Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing

Failure of Autophagy–Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6 nclf Mice

Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure

Development and Validation of the Singapore Thyroid Eye Disease Quality of Life Questionnaire

Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation

Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease

In Vitro Amoebicidal Activity of Titanium Dioxide/UV-A Combination Against Acanthamoeba

Experience-dependent long-term facilitation of skew adaptation

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

Identification and Visualization of a Distinct Microbiome in Ocular Surface Conjunctival Tissue

TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway

Detection of Complement Activators in Immune Attack Eyes After iPS-Derived Retinal Pigment Epithelial Cell Transplantation

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