Retina

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Retina November 2018

Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

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Michael T. Massengill; Brianna Young; Deep Patel; Farwa Jafri; Ernesto Sabogal; Neil Ash; Hong Li; Cristhian J. Ildefonso; Alfred S. Lewin
TAGS: photoreceptors, retinal degeneration, retinitis pigmentosa, mice, retina, outcome measures, spectral-domain optical coherence tomography, rhodopsin
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5417-5430. doi: 10.1167/iovs.18-25345

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2018

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

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Yong Lin; Li Li; Junjie Liu; Xiaoting Zhao; Juxiu Ye; Peter S. Reinach; Jia Qu; Dongsheng Yan
TAGS: angiogenesis, vascular endothelial growth factor a, western blotting, endothelial cells, vascular endothelial growth factor receptor-2, down-regulation, mice, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5431-5440. doi: 10.1167/iovs.17-23558

Includes: Supplemental Content

Anatomy and Pathology/Oncology November 2018

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

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Maria Teresa B. C. Bonanomi; Osmar C. Saito; Patricia Picciarelli de Lima; Roberta Chizzotti Bonanomi; Maria Cristina Chammas
TAGS: doppler color flow, vascular flow, doppler echocardiography, retinoblastoma, eye, neoplasms, optic nerve, particle image velocimetry
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5441-5446. doi: 10.1167/iovs.18-24777

Retina November 2018

Time-Course Change in Eye Shape and Development of Staphyloma in Highly Myopic Eyes

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Tomotaka Wakazono; Kenji Yamashiro; Masahiro Miyake; Masayuki Hata; Manabu Miyata; Akihito Uji; Hideo Nakanishi; Akio Oishi; Hiroshi Tamura; Sotaro Ooto; Akitaka Tsujikawa
TAGS: myopia, time factors, eye, heterogeneity of variance, shape, staphyloma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5455-5461. doi: 10.1167/iovs.18-24754

Articles November 2018

Noninvasive Assessment of Retinal Blood Flow Using a Novel Handheld Laser Speckle Contrast Imager

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Abhishek Rege; Samantha I. Cunningham; Yusi Liu; Karan Raje; Sachin Kalarn; M. Jason Brooke; Lisa Schocket; Sunni Scott; Asifa Shafi; Luis Toledo; Osamah J. Saeedi
TAGS: vascular flow, lasers, diagnostic imaging, fundus photography, mobile devices
Trans. Vis. Sci. Tech.. 2018; 7(6):7. doi: 10.1167/tvst.7.6.7

Letters to the Editor November 2018

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Edoardo Midena; Elisabetta Pilotto; Silvia Bini
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5366-5366. doi: 10.1167/iovs.18-25611

Letters to the Editor November 2018

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

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Hyungwoo Lee; Hyewon Chung
TAGS: biological markers, retinitis, macular edema, diabetic
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5367-5367. doi: 10.1167/iovs.18-25825

Genetics November 2018

Spectrum of Variants in 389 Chinese Probands With Familial Exudative Vitreoretinopathy

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Jia-Kai Li; Yian Li; Xiang Zhang; Chun-Li Chen; Yu-Qing Rao; Ping Fei; Qi Zhang; Peiquan Zhao; Jing Li
TAGS: cohort studies, genes, proband, chinese people, chinese (other dialects), familial exudative vitreoretinopathy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5368-5381. doi: 10.1167/iovs.17-23541

Includes: Supplemental Content

Retina November 2018

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

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Shueh Wen Lim; Esther Bandala-Sanchez; Maria Kolic; Sophie L. Rogers; Annie K. McAuley; Lyndell L. Lim; Sanjeewa S. Wickremasinghe
TAGS: cytokine, vascular endothelial growth factor a, inflammation, eye, macular edema, diabetic, ranibizumab
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5382-5390. doi: 10.1167/iovs.17-23325

Includes: Supplemental Content

Retina November 2018

Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization

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Steven Hyun Seung Lee; Hee Jong Kim; Oh Kyu Shin; Jun-Sub Choi; Jin Kim; Young-Hwa Cho; Joohun Ha; Tae Kwann Park; Joo Yong Lee; Keerang Park; Heuiran Lee
TAGS: vascular endothelial growth factor a, vegfr-1, choroidal neovascularization, mice, bevacizumab, intravitreal injections, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5398-5407. doi: 10.1167/iovs.18-24926

Includes: Supplemental Content

Articles November 2018

Intravitreal Trimethoprim and Sulfamethoxazole Toxicity to the Retina of Albino Rabbits

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Orit Mazza; Zohar Habot-Wilner; Jonathan Shahar; Irit Mann; Anat Loewenstein; Ido Perlman
TAGS: albinism, electroretinography, evoked potentials, visual, follow-up, oryctolagus cuniculus, sulfamethoxazole, trimethoprim, trimethoprim-sulfamethoxazole combination, eye, retina, toxic effect, intravitreal injections
Trans. Vis. Sci. Tech.. 2018; 7(6):2. doi: 10.1167/tvst.7.6.2

Retina November 2018

The Henle Fiber Layer in Albinism: Comparison to Normal and Relationship to Outer Nuclear Layer Thickness and Foveal Cone Density

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Daniel J. Lee; Erica N. Woertz; Alexis Visotcky; Melissa A. Wilk; Heather Heitkotter; Rachel E. Linderman; Sergey Tarima; C. Gail Summers; Brian P. Brooks; Murray H. Brilliant; Bhavna J. Antony; Brandon J. Lujan; Joseph Carroll
TAGS: albinism, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5336-5348. doi: 10.1167/iovs.18-24145

Includes: Multimedia, Supplemental Content

Retina November 2018

An iTRAQ-Based Quantitative Proteomic Analysis of Plasma Proteins in Preterm Newborns With Retinopathy of Prematurity

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Magdalena Zasada; Maciej Suski; Renata Bokiniec; Monika Szwarc-Duma; Maria Katarzyna Borszewska-Kornacka; Józef Madej; Beata Bujak-Giżycka; Anna Madetko-Talowska; Cecilie Revhaug; Lars O. Baumbusch; Ola D. Saugstad; Jacek Józef Pietrzyk; Przemko Kwinta
TAGS: fibrinogen, child, gestational age, hospitalization, newborn, plasma, proteome, retinopathy of prematurity, proteins, plasma proteins
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5312-5319. doi: 10.1167/iovs.18-24914

Special Issue November 2018

Slowed Dark Adaptation in Early AMD: Dual Stimulus Reveals Scotopic and Photopic Abnormalities

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Humza J. Tahir; Elena Rodrigo-Diaz; Neil R. A. Parry; Jeremiah M. F. Kelly; David Carden; Tariq M. Aslam; Ian J. Murray
TAGS: retinal cone, dark adaptation, recovery of function, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD202-AMD210. doi: 10.1167/iovs.18-24227

Glaucoma November 2018

Microtubule Imaging Reveals Cytoskeletal Deficit Predisposing the Retinal Ganglion Cell Axons to Atrophy in DBA/2J

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Denis Sharoukhov; Festa Bucinca-Cupallari; Hyungsik Lim
TAGS: glaucoma, atrophy, axon, cytoskeleton, microtubules, retinal ganglion cells, diagnostic imaging, mice, retina, morphology, language morphology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5292-5300. doi: 10.1167/iovs.18-24150

Includes: Supplemental Content

Glaucoma October 2018

Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study

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Chun-Yan Wang; Yan-Fei Zheng; Bin Liu; Zi-Wei Meng; Fei Hong; Xiao-xia Wang; Xiao-Juan Wang; Lagan Du; Ian Y. Wang; Dan Zhu; Yong Tao; Qi Sheng You; Jost B. Jonas
TAGS: child, refractive errors, eye, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5285-5291. doi: 10.1167/iovs.18-25418

Articles October 2018

Retinotopic Responses in the Visual Cortex Elicited by Epiretinal Electrical Stimulation in Normal and Retinal Degenerate Rats

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Kiran Nimmagadda; James D. Weiland
TAGS: electric stimulation, visual cortex, rats, retina
Trans. Vis. Sci. Tech.. 2018; 7(5):33. doi: 10.1167/tvst.7.5.33

Includes: Supplemental Content

Special Issue October 2018

Maximum Reading Speed in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

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Rohit Varma; Eric H. Souied; Adnan Tufail; Elizabeth Tschosik; Daniela Ferrara; Jiameng Zhang; David Silverman; Chantal Dolan; Neil M. Bressler
TAGS: atrophy, reading (activity), eye, age-related macular degeneration, reading speed
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD195-AMD201. doi: 10.1167/iovs.18-24238

Retina October 2018

Variation of Retinal and Choroidal Vasculatures in Patients With Age-Related Macular Degeneration

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Boram Lee; Jaemoon Ahn; Cheolmin Yun; Seong-woo Kim; Jaeryung Oh
TAGS: angiogram, choroid, eye, age-related macular degeneration, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5246-5255. doi: 10.1167/iovs.17-23600

Includes: Supplemental Content

Retina October 2018

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

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Ling Chen; Xiongze Zhang; Miaoling Li; Yuhong Gan; Feng Wen
TAGS: drusen, lipids, indocyanine green angiography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5237-5245. doi: 10.1167/iovs.18-25124

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Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

SIRT1 Deletion Impairs Retinal Endothelial Cell Migration Through Downregulation of VEGF-A/VEGFR-2 and MMP14

Blood Flow in Monocular Retinoblastoma Assessed by Color Doppler and Correlations With High-Risk Pathologic Features

Time-Course Change in Eye Shape and Development of Staphyloma in Highly Myopic Eyes

Noninvasive Assessment of Retinal Blood Flow Using a Novel Handheld Laser Speckle Contrast Imager

Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

Author Response: Hyperreflective Intraretinal Foci as an OCT Biomarker of Retinal Inflammation in Diabetic Macular Edema

Spectrum of Variants in 389 Chinese Probands With Familial Exudative Vitreoretinopathy

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization

Intravitreal Trimethoprim and Sulfamethoxazole Toxicity to the Retina of Albino Rabbits

The Henle Fiber Layer in Albinism: Comparison to Normal and Relationship to Outer Nuclear Layer Thickness and Foveal Cone Density

An iTRAQ-Based Quantitative Proteomic Analysis of Plasma Proteins in Preterm Newborns With Retinopathy of Prematurity

Slowed Dark Adaptation in Early AMD: Dual Stimulus Reveals Scotopic and Photopic Abnormalities

Microtubule Imaging Reveals Cytoskeletal Deficit Predisposing the Retinal Ganglion Cell Axons to Atrophy in DBA/2J

Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study

Retinotopic Responses in the Visual Cortex Elicited by Epiretinal Electrical Stimulation in Normal and Retinal Degenerate Rats

Maximum Reading Speed in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Variation of Retinal and Choroidal Vasculatures in Patients With Age-Related Macular Degeneration

Drusen and Age-Related Scattered Hypofluorescent Spots on Late-Phase Indocyanine Green Angiography, a Candidate Correlate of Lipid Accumulation

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