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Articles April 2019

Heated and Humidified High Flow Nasal Canal Oxygen Supplementation as an Effective Treatment for High-Risk Prethreshold Retinopathy of Prematurity

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Xian Zhang; Gaoxiang Wang; Binbin Liu; Bo Chen; Hong Yang
TAGS: infant, retinopathy of prematurity, nose, treatment effectiveness, high-flow nasal cannulas, oxygen supplementation, fluid flow
Trans. Vis. Sci. Tech.. 2019; 8(2):20. doi: 10.1167/tvst.8.2.20

Includes: Supplemental Content

Retinal Cell Biology April 2019

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

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Adam Thompson; Martin Berry; Ann Logan; Zubair Ahmed
TAGS: rapamycin, peptides, neuronal outgrowth, rna, messenger, retinal ganglion cells, axon, neurites
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1748-1759. doi: 10.1167/iovs.18-26449

Retina April 2019

Dark-Adapted Two-Color Fundus-Controlled Perimetry in Macular Telangiectasia Type 2

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Tjebo F. C. Heeren; Simone Tzaridis; Roberto Bonelli; Maximilian Pfau; Marcus Fruttiger; Mali Okada; Catherine Egan; Peter Charbel Issa; Frank G. Holz
TAGS: color, perimetry, rod photoreceptors, telangiectasis, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1760-1767. doi: 10.1167/iovs.18-25360

Retina April 2019

Visual Acuity in Pathological Myopia Is Correlated With the Photoreceptor Myoid and Ellipsoid Zone Thickness and Affected by Choroid Thickness

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Jie Ye; Meixiao Shen; Shenghai Huang; Yuchen Fan; Aixia Yao; Chen Pan; Xiutong Shi; Fan Lu; Yilei Shao
TAGS: myopia, photoreceptors, visual acuity, choroid, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1714-1723. doi: 10.1167/iovs.18-26086

Includes: Supplemental Content

Retina April 2019

Development of a Pde6b Gene Knockout Rat Model for Studies of Degenerative Retinal Diseases

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Joon Hyung Yeo; Bok Kyoung Jung; Heuiran Lee; In-Jeoung Baek; Young Hoon Sung; Hae-Sol Shin; Hong Kyung Kim; Kyoung Yul Seo; Joo Yong Lee
TAGS: phenotype, electroretinography, in situ nick-end labeling, retinal degeneration, retinal diseases, mice, rats, retina, fundus photography, gene knockout techniques, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1519-1526. doi: 10.1167/iovs.18-25556

Includes: Supplemental Content

Lecture April 2019

Introducing Artur V. Cideciyan and Samuel G. Jacobson, the 2018 Recipients of the Proctor Medal

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Elise Héon; Gustavo D. Aguirre
TAGS: gene therapy, mutation, blindness, child, dog, domestic, genes, animal model, natural history, ophthalmology, photoreceptors, retinal degeneration, retinal diseases, safety, vision, visual impairment, diagnostic imaging, eye, genetics, retina, x-linked inheritance, autosomal recessive inheritance, tissue degeneration, proof of concept studies
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1677-1679. doi: 10.1167/iovs.19-26884

Lecture April 2019

Leber Congenital Amaurosis (LCA): Potential for Improvement of Vision

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Artur V. Cideciyan; Samuel G. Jacobson
TAGS: retinal cone, photoreceptors, rod photoreceptors, vision, eye, leber's amaurosis
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1680-1695. doi: 10.1167/iovs.19-26672

Retina April 2019

Surface-Modified Melphalan Nanoparticles for Intravitreal Chemotherapy of Retinoblastoma

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Lee B. Sims; Kevin M. Tyo; Sanaya Stocke; Mohamed Y. Mahmoud; Aparna Ramasubramanian; Jill M. Steinbach-Rankins
TAGS: chemotherapy regimen, melphalan, retinoblastoma
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1696-1705. doi: 10.1167/iovs.18-26251

Includes: Supplemental Content

Article April 2019

Visual orientation uncertainty in the rod-and-frame illusion

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Antonella Pomante; Luc P. J. Selen; W. Pieter Medendorp
TAGS: illusions, rod photoreceptors, stroke volume variation
Journal of Vision. 2019; 19(4):19. doi: 10.1167/19.4.19

Includes: Supplemental Content

Articles April 2019

Differential Artery–Vein Analysis Improves the Performance of OCTA Staging of Sickle Cell Retinopathy

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Minhaj Alam; Jennifer I. Lim; Devrim Toslak; Xincheng Yao
TAGS: sickle cell retinopathy
Trans. Vis. Sci. Tech.. 2019; 8(2):3. doi: 10.1167/tvst.8.2.3

Visual Neuroscience April 2019

ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice

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Run-Ze Cui; Lu Wang; Sheng-Nan Qiao; Yong-Chen Wang; Xin Wang; Fei Yuan; Shi-Jun Weng; Xiong-Li Yang; Yong-Mei Zhong
TAGS: diabetes mellitus, streptozocin, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1644-1656. doi: 10.1167/iovs.18-26359

Retina April 2019

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

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Bruce A. Berkowitz; Robert H. Podolsky; Karen M. Lins-Childers; Yichao Li; Haohua Qian
TAGS: oxidative stress, diltiazem, mice, apraxia of speech, aneurysms-osteoarthritis syndrome, saline solutions
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1566-1570. doi: 10.1167/iovs.18-26164

Clinical and Epidemiologic Research April 2019

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

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Caroline Brandl; Christiane Brücklmayer; Felix Günther; Martina E. Zimmermann; Helmut Küchenhoff; Horst Helbig; Bernhard H. F. Weber; Iris M. Heid; Klaus J. Stark
TAGS: sample size, biological response modifiers, color, photoreceptors, reference values, software, diagnostic imaging, eye, age-related macular degeneration, reliability, german, spectral-domain optical coherence tomography, surveys
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1581-1594. doi: 10.1167/iovs.18-25332

Includes: Supplemental Content

Retina April 2019

Characteristics of Diabetic Capillary Nonperfusion in Macular and Extramacular White Spots on Optical Coherence Tomography Angiography

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Kazuya Morino; Tomoaki Murakami; Yoko Dodo; Shota Yasukura; Tatsuya Yoshitake; Masahiro Fujimoto; Akitaka Tsujikawa
TAGS: angiogram, diabetes mellitus, blood capillaries, optical coherence tomography, scanning laser ophthalmoscopy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1595-1603. doi: 10.1167/iovs.18-26534

Retinal Cell Biology April 2019

Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

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Xiaokun Han; Jun Kong; M. Elizabeth Hartnett; Haibo Wang
TAGS: oxygen, vascular endothelial growth factor a, cell proliferation, endothelial cells, vascular endothelial growth factor receptor-2, glucose, electroretinography, endothelium, glycolysis, intraperitoneal injections, retinopathy of prematurity, retina, glucose uptake
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1604-1613. doi: 10.1167/iovs.19-26553

Includes: Supplemental Content

Retina April 2019

Cone-Mediated Function Correlates to Altered Foveal Morphology in Preterm-Born Children at School Age

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Wadim Bowl; Sinan Raoof; Birgit Lorenz; Kerstin Holve; Silke Schweinfurth; Knut Stieger; Monika Andrassi-Darida
TAGS: child, retinal cone, perimetry, school (environment), morphology, language morphology, pupillometry, pupil reaction
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1614-1620. doi: 10.1167/iovs.18-24892

Retina April 2019

CHM/REP1 Transcript Expression and Loss of Visual Function in Patients Affected by Choroideremia

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Valentina Di Iorio; Gabriella Esposito; Francesca De Falco; Rosa Boccia; Tiziana Fioretti; Raffaella Colucci; Giuseppe De Rosa; Paolo Melillo; Francesco Salvatore; Francesca Simonelli; Francesco Testa
TAGS: choroideremia, vision, phenotype, genotype
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1547-1555. doi: 10.1167/iovs.18-25501

Retina April 2019

Optical Coherence Tomography Angiography in Mice: Quantitative Analysis After Experimental Models of Retinal Damage

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Corey A. Smith; Michele L. Hooper; Balwantray C. Chauhan
TAGS: fluorescence, perfusion, wounds and injuries, diagnostic imaging, optical coherence tomography, optic nerve, mice, angiogram, injections, respiratory arrest
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1556-1565. doi: 10.1167/iovs.18-26441

Includes: Supplemental Content

Retina April 2019

Longitudinal Assessment of Rod Function in Intermediate Age-Related Macular Degeneration With and Without Reticular Pseudodrusen

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Rose S. Tan; Robyn H. Guymer; Khin-Zaw Aung; Emily Caruso; Chi D. Luu
TAGS: follow-up, rod photoreceptors, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1511-1518. doi: 10.1167/iovs.18-26385

Retina April 2019

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

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Haitao Liu; Jie Tang; Yunpeng Du; Aicha Saadane; Ivy Samuels; Alex Veenstra; Jianying Z. Kiser; Krzysztof Palczewski; Timothy S. Kern
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, photoreceptors, phototransduction, rod photoreceptors, vision, mice, retina, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1538-1546. doi: 10.1167/iovs.18-26433

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Heated and Humidified High Flow Nasal Canal Oxygen Supplementation as an Effective Treatment for High-Risk Prethreshold Retinopathy of Prematurity

Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration

Dark-Adapted Two-Color Fundus-Controlled Perimetry in Macular Telangiectasia Type 2

Visual Acuity in Pathological Myopia Is Correlated With the Photoreceptor Myoid and Ellipsoid Zone Thickness and Affected by Choroid Thickness

Development of a Pde6b Gene Knockout Rat Model for Studies of Degenerative Retinal Diseases

Introducing Artur V. Cideciyan and Samuel G. Jacobson, the 2018 Recipients of the Proctor Medal

Leber Congenital Amaurosis (LCA): Potential for Improvement of Vision

Surface-Modified Melphalan Nanoparticles for Intravitreal Chemotherapy of Retinoblastoma

Visual orientation uncertainty in the rod-and-frame illusion

Differential Artery–Vein Analysis Improves the Performance of OCTA Staging of Sickle Cell Retinopathy

ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice

Outer Retinal Oxidative Stress Measured In Vivo Using QUEnch-assiSTed (QUEST) OCT

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

Characteristics of Diabetic Capillary Nonperfusion in Macular and Extramacular White Spots on Optical Coherence Tomography Angiography

Enhancing Retinal Endothelial Glycolysis by Inhibiting UCP2 Promotes Physiologic Retinal Vascular Development in a Model of Retinopathy of Prematurity

Cone-Mediated Function Correlates to Altered Foveal Morphology in Preterm-Born Children at School Age

CHM/REP1 Transcript Expression and Loss of Visual Function in Patients Affected by Choroideremia

Optical Coherence Tomography Angiography in Mice: Quantitative Analysis After Experimental Models of Retinal Damage

Longitudinal Assessment of Rod Function in Intermediate Age-Related Macular Degeneration With and Without Reticular Pseudodrusen

Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy

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