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Retina July 2019

The Fate and Prognostic Implications of Hyperreflective Crystalline Deposits in Nonneovascular Age-Related Macular Degeneration

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Serena Fragiotta; Pedro Fernández-Avellaneda; Mark P. Breazzano; Christine A. Curcio; Belinda C. S. Leong; Kenneth Kato; Lawrence A. Yannuzzi; K. Bailey Freund
TAGS: age-related macular degeneration, nonexudative, crystal structure, drusen, eye, follow-up, patient prognosis, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3100-3109. doi: 10.1167/iovs.19-26589

Includes: Multimedia, Supplemental Content

Glaucoma July 2019

Increased Optic Nerve Head Capillary Blood Flow in Early Primary Open-Angle Glaucoma

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Stuart K. Gardiner; Grant Cull; Brad Fortune; Lin Wang
TAGS: blood capillaries, cohort studies, eye, glaucoma, open-angle glaucoma, optic disk, vascular flow, cyclophosphamide/doxorubicin/etoposide
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3110-3118. doi: 10.1167/iovs.19-27389

Retina July 2019

Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy

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Katherine Sumarriva; Karan Uppal; Chunyu Ma; David J. Herren; Yating Wang; Isaac M. Chocron; Cassandra Warden; Sabrina L. Mitchell; L. Goodwin Burgess; Megan P. Goodale; Melissa P. Osborn; Allison J. Ferreira; Janice C. Law; Edward F. Cherney; Dean P. Jones; Milam A. Brantley, Jr
TAGS: arginine, carnitine, diabetic retinopathy, metabolites, nonproliferative diabetic retinopathy, diabetes mellitus
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3119-3126. doi: 10.1167/iovs.19-27321

Includes: Supplemental Content

Article July 2019

Computational-observer analysis of illumination discrimination

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Xiaomao Ding; Ana Radonjić; Nicolas P. Cottaris; Haomiao Jiang; Brian A. Wandell; David H. Brainard
TAGS: light, lighting, retinal cone, mosaicism, noise, psychophysics
Journal of Vision. 2019; 19(7):11. doi: 10.1167/19.7.11

Includes: Supplemental Content

Physiology and Pharmacology July 2019

Oral Delivery of the P2Y 12 Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4 −/− Mouse Model of Retinal Degeneration

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Wennan Lu; Keith E. Campagno; Huen-Yee Tso; Aurora Cenaj; Alan M. Laties; Leif G. Carlsson; Claire H. Mitchell
TAGS: mice, photoreceptors, retinal degeneration, ticagrelor, antagonists, administration, oral
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3046-3053. doi: 10.1167/iovs.19-27241

Retina July 2019

Diffusion Tensor Imaging Analysis of White Matter Microstructural Integrity in Infants With Retinopathy of Prematurity

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Seong Joon Ahn; Hyun-Kyung Park; Byung Ro Lee; Hyun Ju Lee
TAGS: diffusion tensor imaging, infant, infant, premature, magnetic resonance imaging, personal integrity, retinopathy of prematurity, white matter, brain
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3024-3033. doi: 10.1167/iovs.18-25849

Includes: Supplemental Content

Visual Neuroscience July 2019

Contributions of the Melanopsin-Expressing Ganglion Cells, Cones, and Rods to the Pupillary Light Response in Obstructive Sleep Apnea

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Gloria L. Duque–Chica; Carolina P. B. Gracitelli; Ana L. A. Moura; Balázs V. Nagy; Kallene S. Vidal; Geraldine de Melo; Augusto Paranhos, Jr; Michel B. Cahali; Dora F. Ventura
TAGS: color, ganglia, melanopsin, obstructive sleep apnea, photoreceptors, vertebrate, pupil, rod photoreceptors, luminance, retinal cone, sleep, pupil constriction
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3002-3012. doi: 10.1167/iovs.19-26944

Includes: Supplemental Content

Articles July 2019

Automatic Characterization of Retinal Blood Flow Using OCT Angiograms

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Omer Aharony; Orly Gal-Or; Asaf Polat; Yoav Nahum; Dov Weinberger; Yair Zimmer
TAGS: angiogram, fractals, vascular flow, blood capillaries
Trans. Vis. Sci. Tech.. 2019; 8(4):6. doi: 10.1167/tvst.8.4.6

Clinical and Epidemiologic Research July 2019

Impact of the Morphologic Characteristics of Optic Disc on Choroidal Thickness in Young Myopic Patients

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Qiuying Chen; Jiangnan He; Yao Yin; Hongfeng Zhou; Huifen Jiang; Jianfeng Zhu; Kyoko Ohno-Matsui; Haidong Zou; Ying Fan; Xun Xu
TAGS: myopia, optic disk, tilted optic disc, atrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2958-2967. doi: 10.1167/iovs.18-26393

Retinal Cell Biology July 2019

In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema

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Rina Namba; Hiroki Kaneko; Ayana Suzumura; Hideyuki Shimizu; Keiko Kataoka; Kei Takayama; Kazuhisa Yamada; Yasuhito Funahashi; Seina Ito; Norie Nonobe; Hiroko Terasaki
TAGS: antibodies, anti-vascular endothelial growth factor therapy, epiretinal membrane, macular edema, diabetic, permeability, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2942-2949. doi: 10.1167/iovs.19-26788

Articles July 2019

The Effect of Haptic Feedback on Efficiency and Safety During Preretinal Membrane Peeling Simulation

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Anibal Francone; Jason Mingyi Huang; Ji Ma; Tsu-Chin Tsao; Jacob Rosen; Jean-Pierre Hubschman
TAGS: epiretinal membrane, feedback, safety, surgical procedures, operative, retina, surgeons
Trans. Vis. Sci. Tech.. 2019; 8(4):2. doi: 10.1167/tvst.8.4.2

Retina July 2019

Photoreceptor Degeneration is Correlated With the Deterioration of Macular Retinal Sensitivity in High Myopia

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Yuanyuan Wang; Jie Ye; Meixiao Shen; Aixia Yao; Anquan Xue; Yuchen Fan; Shenghai Huang; Jianhua Wang; Fan Lu; Yilei Shao
TAGS: myopia, photoreceptors, retinal cone, tissue degeneration, eye, choroid
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2800-2810. doi: 10.1167/iovs.18-26085

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2019

Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity

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Catherine M. Bulka; Olaf Dammann; Hudson P. Santos, Jr; Deborah K. VanderVeen; Lisa Smeester; Raina Fichorova; T. Michael O'Shea; Rebecca C. Fry
TAGS: angiogenesis, genes, inflammation, methylation, placenta, retinopathy of prematurity, newborn
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2888-2894. doi: 10.1167/iovs.18-26466

Retina July 2019

Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors

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Diego F. Buenaventura; Adrianne Corseri; Mark M. Emerson
TAGS: embryo, genes, mice, retina, retinal cone, transcription, genetic, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2787-2799. doi: 10.1167/iovs.19-26951

Includes: Supplemental Content

Glaucoma July 2019

En Face Slab Images Visualize Nerve Fibers With Residual Visual Sensitivity in Significantly Thinned Macular Areas of Advanced Glaucomatous Eyes

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Mari Sakamoto; Sotaro Mori; Kaori Ueda; Takuji Kurimoto; Sentaro Kusuhara; Yuko Yamada-Nakanishi; Makoto Nakamura
TAGS: eye, face, glaucoma, nerve fibers, macula densa, macula lutea, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2811-2821. doi: 10.1167/iovs.18-25910

Genetics July 2019

Genotype–Phenotype Analysis of a Novel Recessive and a Recurrent Dominant SNRNP200 Variant Causing Retinitis Pigmentosa

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Christina Gerth-Kahlert; Samuel Koller; James V. M. Hanson; Luzy Baehr; Amit Tiwari; Fatma Kivrak-Pfiffner; Angela Bahr; Wolfgang Berger
TAGS: family, genotype, phenotype, recurrence, retinitis pigmentosa, missense mutation, mutation, genes, heterozygote, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2822-2835. doi: 10.1167/iovs.18-25643

Visual Neuroscience July 2019

Topography of Neurons in the Rod Pathway of Human Retina

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Sammy C. S. Lee; Paul R. Martin; Ulrike Grünert
TAGS: retina, rod photoreceptors, neurons, retinal bipolar cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2848-2859. doi: 10.1167/iovs.19-27217

Biochemistry and Molecular Biology July 2019

Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells

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Feng He; Ralph M. Nichols; Lavanya Kailasam; Theodore G. Wensel; Melina A. Agosto
TAGS: biopharmaceutics classification system, phosphatidylinositols, phosphotransferases, retinal bipolar cells, tissue degeneration, mice, tissue membrane, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2861-2874. doi: 10.1167/iovs.19-26586

Includes: Supplemental Content

Articles July 2019

Avian Adeno-Associated Viral Transduction of the Postembryonic Chicken Retina

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Derek M. Waldner; Frank Visser; Andy J. Fischer; N. Torben Bech-Hansen; William K. Stell
TAGS: aves, chickens, injections, retina, spatial vectors, photoreceptors
Trans. Vis. Sci. Tech.. 2019; 8(4):1. doi: 10.1167/tvst.8.4.1

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2019

Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study

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Emi Ueda; Miho Yasuda; Kohta Fujiwara; Sawako Hashimoto; Kyoko Ohno-Matsui; Jun Hata; Tatsuro Ishibashi; Toshiharu Ninomiya; Koh-Hei Sonoda
TAGS: japanese, macular disorders, myopia, prevalence, trend
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2781-2786. doi: 10.1167/iovs.19-26580

Includes: Supplemental Content

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The Fate and Prognostic Implications of Hyperreflective Crystalline Deposits in Nonneovascular Age-Related Macular Degeneration

Increased Optic Nerve Head Capillary Blood Flow in Early Primary Open-Angle Glaucoma

Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy

Computational-observer analysis of illumination discrimination

Oral Delivery of the P2Y 12 Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4 −/− Mouse Model of Retinal Degeneration

Diffusion Tensor Imaging Analysis of White Matter Microstructural Integrity in Infants With Retinopathy of Prematurity

Contributions of the Melanopsin-Expressing Ganglion Cells, Cones, and Rods to the Pupillary Light Response in Obstructive Sleep Apnea

Automatic Characterization of Retinal Blood Flow Using OCT Angiograms

Impact of the Morphologic Characteristics of Optic Disc on Choroidal Thickness in Young Myopic Patients

In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema

The Effect of Haptic Feedback on Efficiency and Safety During Preretinal Membrane Peeling Simulation

Photoreceptor Degeneration is Correlated With the Deterioration of Macular Retinal Sensitivity in High Myopia

Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity

Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors

En Face Slab Images Visualize Nerve Fibers With Residual Visual Sensitivity in Significantly Thinned Macular Areas of Advanced Glaucomatous Eyes

Genotype–Phenotype Analysis of a Novel Recessive and a Recurrent Dominant SNRNP200 Variant Causing Retinitis Pigmentosa

Topography of Neurons in the Rod Pathway of Human Retina

Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells

Avian Adeno-Associated Viral Transduction of the Postembryonic Chicken Retina

Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study

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