Retinal Imaging

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Clinical Trials December 2024

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

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Viktoria Pai; Patrick Janku; Theresa Lindner; Ulrich Graf; Leopold Schmetterer; Gerhard Garhöfer; Doreen Schmidl
TAGS: lasers, oximetry, oxygen, oxygen extraction, oxygen saturation measurement, vascular flow, hypoxia, inspiration, respiration, hyperoxia
Trans. Vis. Sci. Tech.. 2024; 13(12):12. https://doi.org/10.1167/tvst.13.12.12

Biochemistry and Molecular Biology December 2024

Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

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Bushra Rahman; David M. G. Anderson; Chunhe Chen; Jian Liu; Lukasz G. Migas; Raf Van de Plas; Kevin L. Schey; Masahiro Kono; Jie Fan; Yiannis Koutalos
TAGS: chromophore, mice, niemann-pick diseases, retina, sphingolipids, vitamin a, spectrometry, mass, matrix-assisted laser desorption-ionization, sphingomyelins, diagnostic imaging, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):24. https://doi.org/10.1167/iovs.65.14.24

Retina December 2024

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

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Chunran Lai; Ting Su; Jiahui Cao; Qinyi Li; Zijing Du; Yaxin Wang; Shan Wang; Qiaowei Wu; Yijun Hu; Ying Fang; Huiyi Liao; Zhuoting Zhu; Xianwen Shang; Mingguang He; Honghua Yu; Xiayin Zhang
TAGS: diabetes mellitus, type 2, diabetic retinopathy, electroretinography, nonproliferative diabetic retinopathy, peripheral neurovascular compromise, photopsia, retinal cone, optical coherence tomography, retina, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):20. https://doi.org/10.1167/iovs.65.14.20

Includes: Supplemental Content

Retina December 2024

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

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Monica Ardon; Lily Nguyen; Rui Chen; Jeffrey Rogers; Tim Stout; Sara Thomasy; Ala Moshiri
TAGS: disease progression, electroretinography, homozygote, infant, mutation, primates, retinal cone, macaca, adult, heterozygote
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):16. https://doi.org/10.1167/iovs.65.14.16

Includes: Supplemental Content

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Retina November 2024

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

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Saman Ebrahimi; Phillip Bedggood; Yifu Ding; Andrew Metha; Prosenjit Bagchi
TAGS: blood capillaries, blood cells, computer simulation, fluid flow, hematocrit, hemodynamics, microcirculation, microvascular network, velocity, retail clinics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):37. https://doi.org/10.1167/iovs.65.13.37

Includes: Multimedia, Supplemental Content

Retinal Cell Biology November 2024

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

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Jimin Han; Sueanne Chear; Jana Talbot; Vicki Swier; Clarissa Booth; Cheyenne Reuben-Thomas; Sonal Dalvi; Jill M. Weimer; Alex W. Hewitt; Anthony L. Cook; Ruchira Singh
TAGS: autofluorescence, phagocytosis, photoreceptors, platypnea orthodeoxia syndrome, retinal pigment cell, tissue degeneration, genetics, lipofuscin, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):23. https://doi.org/10.1167/iovs.65.13.23

Includes: Supplemental Content

Visual Neuroscience November 2024

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

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Zihe Xu; Jit Kai Tan; Krishnika Vetrivel; Xiaofan Jiang; Shaun M. Leo; Taha Bhatti; Ambreen Tariq; Andrew R. Webster; Anthony G. Robson; Christopher J. Hammond; Pirro G. Hysi; Omar A. Mahroo
TAGS: electroretinography, genetic risk, myopia, polymorphism
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):21. https://doi.org/10.1167/iovs.65.13.21

Includes: Supplemental Content

Retina November 2024

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

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Jacqueline Fröhlich; Marco Cattaneo; Philippe Valmaggia; Peter M. Maloca; Konstantin Gugleta; Leopold Schmetterer; Hendrik P.N. Scholl; Giacomo Calzetti
TAGS: laser speckle contrast imaging, optic disk, perfusion, vascular flow, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(11):8. https://doi.org/10.1167/tvst.13.11.8

Includes: Supplemental Content

Retina November 2024

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

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Owen R. Bowie; Hannah M. Follett; Ching Tzu Yu; Chloe Guillaume; Phyllis M. Summerfelt; Nicole Manfredonia; Jenna Grieshop; Dana K. Merriman; Sergey Tarima; Joseph Carroll
TAGS: cohort studies, diagnostic imaging, follow-up, intravitreal injections, retinal cone, scanning laser ophthalmoscopy, seasonal variation, mosaicism, injections, mosaic trial
Trans. Vis. Sci. Tech.. 2024; 13(11):5. https://doi.org/10.1167/tvst.13.11.5

Includes: Supplemental Content

Artificial Intelligence November 2024

Developing a 10-Layer Retinal Segmentation for MacTel Using Semi-Supervised Learning

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Aayush Verma; Simone Tzaridis; Marian Blazes; Martin Friedlander; Aaron Y. Lee; Yue Wu
TAGS: deep learning, learning, datasets, eye, training
Trans. Vis. Sci. Tech.. 2024; 13(11):2. https://doi.org/10.1167/tvst.13.11.2

Includes: Supplemental Content

Retina November 2024

Comparison of Geographic Atrophy Measurements Between Blue-Light Heidelberg Standard Field and Green-Light Optos Ultrawide Field Autofluorescence

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Colin P. Froines; Thomas F. Saunders; Jennifer A. Heathcote; Jeong W. Pak; Emily Y. Chew; Barbara A. Blodi; Amitha Domalpally
TAGS: age-related macular degeneration, nonexudative, autofluorescence, blue light, fundus autofluorescence imaging, green light, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(11):1. https://doi.org/10.1167/tvst.13.11.1

Includes: Supplemental Content

Retina November 2024

Retinal Function in Advanced Multiple Sclerosis

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James V. M. Hanson; Sara Single; Rahel B. Eberle; Veronika Kana; Benjamin V. Ineichen; Christina Gerth-Kahlert
TAGS: electroretinography, multiple sclerosis, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):2. https://doi.org/10.1167/iovs.65.13.2

Includes: Supplemental Content

Review October 2024

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

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Jay Neitz; Maureen Neitz
TAGS: lens (device), myopia, optics, lens, crystalline, eye, retina, diffusion, technology
Trans. Vis. Sci. Tech.. 2024; 13(10):42. https://doi.org/10.1167/tvst.13.10.42

Retina October 2024

Differential Localization and Functional Roles of mGluR6 Paralogs in Zebrafish Retina

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Marion Haug; Sara A. Haddad-Velioglu; Manuela Berger; Anja Enz; Jingjing Zang; Stephan C F. Neuhauss
TAGS: electroretinography, retina, zebrafish, proteins, retinal cone, antibodies, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):44. https://doi.org/10.1167/iovs.65.12.44

Includes: Supplemental Content

Retina October 2024

Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography

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Joshua N. Dang; Jolan Wu; Yujiao Zheng; Jason J. Bunk; Emily K. Tam; Karen E. Lee; Sumner E. Lawson; Tatiana R. Monger; Alex T. Legocki; John P. Kelly; Obiageri Egeolu; Leona Ding; Ruikang K. Wang; Kristina Tarczy-Hornoch; Michelle T. Cabrera
TAGS: infant, macula lutea, mobile devices, optical coherence tomography, infant, premature, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):35. https://doi.org/10.1167/iovs.65.12.35

Article October 2024

Measurements of chromatic adaptation and luminous efficiency while wearing colored filters

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Andrew J. Coia; Joseph M. Arizpe; Peter A. Smith; Thomas K. Kuyk; Julie A. Lovell
TAGS: filters, luminance, retinal cone, color
Journal of Vision. 2024; 24(11):9. https://doi.org/10.1167/jov.24.11.9

Multidisciplinary Ophthalmic Imaging October 2024

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

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Natasa Jeremic; Maximilian Pawloff; Dmitrii Lachinov; Stephanie Rokitansky; Matthias Hasun; Franz Weidinger; Andreas Pollreisz; Hrvoje Bogunović; Ursula Schmidt-Erfurth
TAGS: biological markers, coronary arteriosclerosis, stratification
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):15. https://doi.org/10.1167/iovs.65.12.15

Includes: Supplemental Content

Retinal Cell Biology October 2024

Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation

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Ryutaro Akiba; Hung-Ya Tu; Tomoyo Hashiguchi; Yoshiko Takahashi; Kiminori Toyooka; Yoshihiko Tsukamoto; Takayuki Baba; Masayo Takahashi; Michiko Mandai
TAGS: synapses, tissue transplants, transplantation, photoreceptors, shape, retinal bipolar cells
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):8. https://doi.org/10.1167/iovs.65.12.8

Includes: Supplemental Content

Retina October 2024

Longitudinal Imaging of the Foveal Cone Mosaic in CNGA3 -Associated Achromatopsia

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Mohamed Katta; Michalis Georgiou; Navjit Singh; Angelos Kalitzeos; Alfredo Dubra; Joseph Carroll; Michel Michaelides
TAGS: achromatopsia, diagnostic imaging, mosaicism, retinal cone, mosaic trial
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):6. https://doi.org/10.1167/iovs.65.12.6

Includes: Supplemental Content

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A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

Developing a 10-Layer Retinal Segmentation for MacTel Using Semi-Supervised Learning

Comparison of Geographic Atrophy Measurements Between Blue-Light Heidelberg Standard Field and Green-Light Optos Ultrawide Field Autofluorescence

Retinal Function in Advanced Multiple Sclerosis

Diffusion Optics Technology (DOT): A Myopia Control Spectacle Lens Based on Contrast Theory

Differential Localization and Functional Roles of mGluR6 Paralogs in Zebrafish Retina

Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography

Measurements of chromatic adaptation and luminous efficiency while wearing colored filters

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

Host-Graft Synapses Form Functional Microstructures and Shape the Host Light Responses After Stem Cell-Derived Retinal Sheet Transplantation

Longitudinal Imaging of the Foveal Cone Mosaic in CNGA3 -Associated Achromatopsia

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