Translational Research

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Retina January 2025

High-Resolution OCT Reveals Age-Associated Variation in the Region Posterior to the External Limiting Membrane

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Muhammad Usman Jamil; Jungeun Won; Stefan B. Ploner; Anna Marmalidou; Hiroyuki Takahashi; Stephanie Kaiser; Yunchan Hwang; Omar Abu-Qamar; Antonio Yaghy; Andre J. Witkin; Peter Y. Zhao; Shilpa Desai; Jay S. Duker; Andreas Maier; James G. Fujimoto; Nadia K. Waheed
TAGS: embryonic lethal mutation, tissue membrane, diagnostic imaging, volume, motion
Trans. Vis. Sci. Tech.. 2025; 14(1):16. https://doi.org/10.1167/tvst.14.1.16

Includes: Supplemental Content

Letters to the Editor January 2025

An Alternative Mechanism for the Anti-Myopia Effectiveness of Diffusion Optics Technology (DOT) Lenses

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Timothy J. Gawne; Safal Khanal; Thomas T. Norton
TAGS: diffusion, lens (device), lens, crystalline, myopia, optics, technology
Trans. Vis. Sci. Tech.. 2025; 14(1):15. https://doi.org/10.1167/tvst.14.1.15

Review January 2025

New Directions for Ophthalmic OCT – Handhelds, Surgery, and Robotics

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Julia Foust; Morgan McCloud; Amit Narawane; Robert M. Trout; Xi Chen; Al-Hafeez Dhalla; Jianwei D. Li; Christian Viehland; Mark Draelos; Lejla Vajzovic; Ryan P. McNabb; Anthony N. Kuo; Cynthia A. Toth
TAGS: eye, intraoperative care, robotics, surgical procedures, operative, diagnostic imaging, mobile devices
Trans. Vis. Sci. Tech.. 2025; 14(1):14. https://doi.org/10.1167/tvst.14.1.14

Low Vision Rehabilitation January 2025

Performance on Activities of Daily Living and User Experience When Using Artificial Intelligence by Individuals With Vision Impairment

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William Seiple; Hilde P. A. van der Aa; Fernanda Garcia-Piña; Izekiel Greco; Calvin Roberts; Ruth van Nispen
TAGS: activities of daily living, artificial intelligence, blindness, visual impairment, perception
Trans. Vis. Sci. Tech.. 2025; 14(1):3. https://doi.org/10.1167/tvst.14.1.3

Erratum January 2025

Erratum in: Focused Ultrasound as a Novel Non-Invasive Method for the Delivery of Gold Nanoparticles to Retinal Ganglion Cells

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Trans. Vis. Sci. Tech.. 2025; 14(1):13. https://doi.org/10.1167/tvst.14.1.13

Retina January 2025

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

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Katharina Wall; Lilith P. Arend; Leon von der Emde; Marlene Saßmannshausen; Frank G. Holz; Thomas Ach
TAGS: diabetes mellitus, diagnostic imaging, optical coherence tomography, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2025; 14(1):12. https://doi.org/10.1167/tvst.14.1.12

Retina January 2025

Comparison of a Novel Ultra-Widefield Three-Color Scanning Laser Ophthalmoscope to Other Retinal Imaging Modalities in Chorioretinal Lesion Imaging

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Ines D. Nagel; Anna Heinke; Akshay P. Agnihotri; Shaden Yassin; Lingyun Cheng; Andrew S. Camp; Nathan L. Scott; Fritz Gerald P. Kalaw; Shyamanga Borooah; Dirk-Uwe G. Bartsch; Arthur J. Mueller; Nehal Mehta; William R. Freeman
TAGS: color, diagnostic imaging, lasers, minimal cognitive impairment, ophthalmoscopes, retinal imaging
Trans. Vis. Sci. Tech.. 2025; 14(1):11. https://doi.org/10.1167/tvst.14.1.11

Retina January 2025

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

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Brandon D. Anderson; Brent A. Bell; Ying Song; Timothy T. Lee; Tan Wang; Joshua L. Dunaief
TAGS: age-related macular degeneration, nonexudative, atrophy, injections, iodates, sodium, mice, diagnostic imaging, retina
Trans. Vis. Sci. Tech.. 2025; 14(1):9. https://doi.org/10.1167/tvst.14.1.9

Includes: Supplemental Content

Public Health January 2025

Social Determinants of Uncorrected Distance and Near Visual Impairment in an Older Adult Population

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Po-Jen Lin; Alison G. Abraham; Pradeep Ramulu; Aleks Mihailovic; Anna Kucharska-Newton; Xinxing Guo
TAGS: community, eye, older adult, social determinants of health, visual impairment, physicians, aric trial, health, income
Trans. Vis. Sci. Tech.. 2025; 14(1):8. https://doi.org/10.1167/tvst.14.1.8

Includes: Supplemental Content

Retina January 2025

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

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Federico Corti; Filippo Locri; Flavia Plastino; Paola Perrotta; Krisztina Zsebo; Emma Ristori; Xiangyun Yin; Eric Song; Helder André; Michael Simons
TAGS: antibodies, choroidal neovascularization, edema, inflammation, lasers, mice, syndecan, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, intravitreal injections
Trans. Vis. Sci. Tech.. 2025; 14(1):10. https://doi.org/10.1167/tvst.14.1.10

Includes: Supplemental Content

Retina January 2025

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

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Shuqi You; Suqian Wu; Shicheng Yang; Zhenyang Zhao; Wei Chen; Xiangwu Chen; Huan Wang; Qing Xia; Jiawei Xiong; Hongsheng Zhou; Xiaofen Mo
TAGS: drug delivery systems, pus, sclera, ultrasonography, nipple discharge aspiration, sodium fluoride
Trans. Vis. Sci. Tech.. 2025; 14(1):7. https://doi.org/10.1167/tvst.14.1.7

Includes: Supplemental Content

Artificial Intelligence January 2025

Conjunctival Bulbar Redness Extraction Pipeline for High-Resolution Ocular Surface Photography

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Philipp Ostheimer; Arno Lins; Lars Albert Helle; Vito Romano; Bernhard Steger; Marco Augustin; Daniel Baumgarten
TAGS: conjunctiva, datasets, eye, iris, ocular surfaces, photography, diagnostic imaging
Trans. Vis. Sci. Tech.. 2025; 14(1):6. https://doi.org/10.1167/tvst.14.1.6

Retina January 2025

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

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Shizhen Lei; Yani Liu
TAGS: gastrointestinal microbiome, genetic correlation analysis, genetics, mendelian randomization analysis, retinal vein occlusion
Trans. Vis. Sci. Tech.. 2025; 14(1):5. https://doi.org/10.1167/tvst.14.1.5

Includes: Supplemental Content

Pediatric Ophthalmology & Strabismus January 2025

The Associations Between Myopia and Fundus Tessellation in School Children: A Comparative Analysis of Macular and Peripapillary Regions Using Deep Learning

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Dan Huang; Xiao Lin; Hui Zhu; Saiguang Ling; Zhou Dong; Xin Ke; Tengfei Long; Yingxiao Qian; Qi Yan; Rui Li; Hua Zhong; Hu Liu
TAGS: deep learning, frontotemporal dementia, myopia, school-age child
Trans. Vis. Sci. Tech.. 2025; 14(1):4. https://doi.org/10.1167/tvst.14.1.4

Includes: Supplemental Content

Glaucoma January 2025

In Vitro Analysis of Pressure Resistance in the Paul Glaucoma Implant and Ahmed ClearPath 250 With and Without Polypropylene Thread Inside the Tube

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Andi Masdipa; Sachiko Kaidzu; Masaki Tanito
TAGS: glaucoma, implants, polypropylenes
Trans. Vis. Sci. Tech.. 2025; 14(1):2. https://doi.org/10.1167/tvst.14.1.2

Low Vision Rehabilitation January 2025

How People With Vision Impairment Use Their Gaze to Hit a Ball

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Ward Nieboer; Carin M. Svensen; Kjell van Paridon; Debbie Van Biesen; David L. Mann
TAGS: gaze, visual impairment, eye, peripheral vision
Trans. Vis. Sci. Tech.. 2025; 14(1):1. https://doi.org/10.1167/tvst.14.1.1

Retina December 2024

The Effects of Anti-Vascular Endothelial Growth Factor Loading Injections on Retinal Microvasculature in Diabetic Macular Edema

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Kiyoung Kim; Junwoo Lee; Seung-Young Yu
TAGS: anti-vascular endothelial growth factor therapy, diabetic macular edema, endothelial growth factors, injections, retinal vasculature, nasopharyngeal aspirate
Trans. Vis. Sci. Tech.. 2024; 13(12):37. https://doi.org/10.1167/tvst.13.12.37

Editorial December 2024

Reviewers

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TAGS: bsnd gene, gangs, happiness, laparoscopic uterosacral nerve ablation, reading (activity), tolnaftate, acetylcholine, achondroplasia, camurati-engelmann syndrome, e-selectin
Trans. Vis. Sci. Tech.. 2024; 13(12):38. https://doi.org/10.1167/tvst.13.12.38

Lens December 2024

Acoustic Radiation Force Optical Coherence Elastography of the Crystalline Lens: Safety

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Christian Zevallos-Delgado; Taye Tolu Mekonnen; Chaitanya Duvvuri; Leana Rohman; Justin Schumacher; Manmohan Singh; Salavat R. Aglyamov; Michael D. Twa; Jean-Marie Parel; Giuliano Scarcelli; Fabrice Manns; Kirill V. Larin
TAGS: acoustics, elasticity imaging techniques, lens, crystalline, optics, radiation, safety
Trans. Vis. Sci. Tech.. 2024; 13(12):36. https://doi.org/10.1167/tvst.13.12.36

Retina December 2024

Changes in Aqueous Angiopoietin-1/2 Concentrations During the Induction Phase of Intravitreal Faricimab Injections for Diabetic Macular Edema

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Masahiko Shimura; Shotaro Sasaki; Ryota Nonaka; Ikumi Kashiwagi; Kanako Yasuda; Hidetaka Noma; Hitoshi Takagi
TAGS: angiopoietins, cytokine, diabetic macular edema, faricimab, injections, vascular endothelial growth factor a
Trans. Vis. Sci. Tech.. 2024; 13(12):35. https://doi.org/10.1167/tvst.13.12.35

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High-Resolution OCT Reveals Age-Associated Variation in the Region Posterior to the External Limiting Membrane

An Alternative Mechanism for the Anti-Myopia Effectiveness of Diffusion Optics Technology (DOT) Lenses

New Directions for Ophthalmic OCT – Handhelds, Surgery, and Robotics

Performance on Activities of Daily Living and User Experience When Using Artificial Intelligence by Individuals With Vision Impairment

Erratum in: Focused Ultrasound as a Novel Non-Invasive Method for the Delivery of Gold Nanoparticles to Retinal Ganglion Cells

Characterization of the Disorganization of the Inner Retinal Layers in Diabetics Using Increased Axial Resolution Optical Coherence Tomography

Comparison of a Novel Ultra-Widefield Three-Color Scanning Laser Ophthalmoscope to Other Retinal Imaging Modalities in Chorioretinal Lesion Imaging

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

Social Determinants of Uncorrected Distance and Near Visual Impairment in an Older Adult Population

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

Pulsed Ultrasound-Mediated Drug Delivery Enhancement Through Human Sclera

Conjunctival Bulbar Redness Extraction Pipeline for High-Resolution Ocular Surface Photography

Identifying the Involvement of Gut Microbiota in Retinal Vein Occlusion by Mendelian Randomization and Genetic Correlation Analysis

The Associations Between Myopia and Fundus Tessellation in School Children: A Comparative Analysis of Macular and Peripapillary Regions Using Deep Learning

In Vitro Analysis of Pressure Resistance in the Paul Glaucoma Implant and Ahmed ClearPath 250 With and Without Polypropylene Thread Inside the Tube

How People With Vision Impairment Use Their Gaze to Hit a Ball

The Effects of Anti-Vascular Endothelial Growth Factor Loading Injections on Retinal Microvasculature in Diabetic Macular Edema

Reviewers

Acoustic Radiation Force Optical Coherence Elastography of the Crystalline Lens: Safety

Changes in Aqueous Angiopoietin-1/2 Concentrations During the Induction Phase of Intravitreal Faricimab Injections for Diabetic Macular Edema

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